| Eric Alonzo | P | 25.315 | Miami Marlins | Jacksonville (AA) | Assigned to Jacksonville (AA) |
| Olivier Basabe | ss | 19.358 | | Arizona Padres 2 (Rk) | Assigned to Nashville (AAA) |
| Kyle Beam | 1b | 22.154 | Milwaukee Brewers | Helena (Rk) | Assigned to Helena (Rk) |
| Cody Beckman | p | 22.249 | Milwaukee Brewers | Helena (Rk) | Assigned to Helena (Rk) |
| TJ Bennett | if | 24.351 | San Francisco Giants | Sacramento (AAA) | Assigned to Sacramento (AAA) |
| Marino Campana | of | 19.222 | Boston Red Sox | Lowell (A-) | Assigned to Lowell (A-) |
| Alex Castellanos | lf | 30.338 | Baltimore Orioles | Norfolk (AAA) | Activated from disabled list |
| Luis Cessa | SP | 25.074 | New York Yankees | Scranton/Wilkes-Barre (AAA) | Assigned to Scranton/Wilkes-Barre (AAA) |
| Scott Copeland | SP | 29.206 | Miami Marlins | New Orleans (AAA) | Assigned to New Orleans (AAA) |
| Edgar Corcino | 3B | 25.031 | Minnesota Twins | Rochester (AAA) | Assigned to Rochester (AAA) |
| Nelvin Correa | p | 20.164 | New York Yankees | Gulf Coast Yankees (Rk) | Assigned to Gulf Coast Yankees (Rk) |
| Nestor Cortes | P | 22.210 | New York Yankees | Scranton/Wilkes-Barre (AAA) | Assigned to Scranton/Wilkes-Barre (AAA) |
| Collin Cowgill | LF | 31.047 | San Diego Padres | Arizona Padres (Rk) | Assigned to Arizona Padres (Rk) |
| Galli Cribbs | IF | 24.273 | Arizona Diamondbacks | Visalia (A+) | Assigned to Visalia (A+) |
| Weston Davis | P | 21.002 | Washington Nationals | Auburn (A-) | Assigned to Auburn (A-) |
| Enmanuel De Jesus | p | 20.210 | Boston Red Sox | Lowell (A-) | Assigned to Lowell (A-) |
| Juan De La Cruz | C | 23.337 | Cleveland Indians | Akron (AA) | Activated from disabled list |
| Seth Elledge | p | 21.049 | Seattle Mariners | Clinton (A) | Assigned to Clinton (A) |
| Pedro Espinola | p | 21.158 | New York Yankees | Gulf Coast Yankees (Rk) | Assigned to Gulf Coast Yankees (Rk) |
| Luke Eubank | P | 23.134 | Cleveland Indians | Lake County (A) | Assigned to Lake County (A) |
| Tyler Fallwell | p | 21.243 | Kansas City Royals | Burlington (Rk) | Assigned to Burlington (Rk) |
| Juan Florentino | p | 20.303 | Boston Red Sox | Lowell (A-) | Assigned to Lowell (A-) |
| Isaac Galloway | CF | 27.271 | Miami Marlins | Gulf Coast Marlins (Rk) | Assigned to Gulf Coast Marlins (Rk) |
| Junior Garcia | P | 21.281 | Arizona Diamondbacks | Kane County (A) | Assigned to Kane County (A) |
| Julio Gonzalez | ss | 22.024 | Kansas City Royals | Idaho Falls (Rk) | Assigned to Idaho Falls (Rk) |
| Cade Gotta | OF | 25.342 | Tampa Bay Rays | Montgomery (AA) | Assigned to Montgomery (AA) |
| Matthew Hardy | p | 21.359 | Milwaukee Brewers | Helena (Rk) | Assigned to Helena (Rk) |
| Tyler Heineman | C | 26.019 | Milwaukee Brewers | Colorado Springs (AAA) | Assigned to Colorado Springs (AAA) |
| Sam Hentges | P | 20.355 | Cleveland Indians | Arizona Indians (Rk) | Activated from disabled list |
| Tyler Herb | P | 25.071 | San Francisco Giants | Richmond (AA) | Assigned to Richmond (AA) |
| Matt Holliday | DH | 37.189 | New York Yankees | Scranton/Wilkes-Barre (AAA) | Assigned to Scranton/Wilkes-Barre (AAA) for rehab |
| Wei-Chieh Huang | p | 23.285 | Arizona Diamondbacks | Kane County (A) | Activated from disabled list |
| Dane Hutcheon | ss | 22.359 | Minnesota Twins | Fort Myers (A+) | Assigned to Fort Myers (A+) |
| David Jacob | 1b | 22.019 | Toronto Blue Jays | Gulf Coast Blue Jays (Rk) | Assigned to Gulf Coast Blue Jays (Rk) |
| Micah Johnson | LF | 26.202 | Atlanta Braves | Rome (A) | Assigned to Rome (A) for rehab |
| Stephen Johnson | P | 26.137 | San Francisco Giants | Richmond (AA) | Assigned to Richmond (AA) |
| Travis Jones | of | 21.283 | Kansas City Royals | Burlington (Rk) | Assigned to Burlington (Rk) |
| Jeff Kemp | IF | 27.107 | Baltimore Orioles | Bowie (AA) | Activated from disabled list |
| Nick King | ss | 23.238 | Pittsburgh Pirates | West Virginia (A) | Assigned to West Virginia (A) |
| Will LaMarche | P | 25.336 | San Francisco Giants | Sacramento (AAA) | Assigned to Sacramento (AAA) |
| Domingo Leyba | 2B | 21.301 | Arizona Diamondbacks | Jackson (AA) | Activated from disabled list |
| Ryan Lillie | p | 21.068 | Miami Marlins | Batavia (A-) | Assigned to Batavia (A-) |
| Dominic LoBrutto | p | 21.038 | Boston Red Sox | Lowell (A-) | Assigned to Lowell (A-) |
| Justin Maffei | OF | 25.316 | Pittsburgh Pirates | Altoona (AA) | Assigned to Altoona (AA) |
| Joey Martarano | 3B | 22.345 | Chicago Cubs | Eugene (A-) | Assigned to Eugene (A-) |
| Yonathan Mendoza | 3b | 23.148 | Cleveland Indians | Akron (AA) | Assigned to Akron (AA) |
| Julian Merryweather | P | 25.268 | Cleveland Indians | Columbus (AAA) | Activated from disabled list |
| Charlie Meyer | c | 24.179 | Milwaukee Brewers | Carolina (A+) | Assigned to Carolina (A+) |
| Craig Missigman | P | 23.337 | New York Mets | St. Lucie (A+) | Activated from disabled list |
| Bryan Mitchell | RP | 26.080 | New York Yankees | Tampa (A+) | Assigned to Tampa (A+) |
| Joseph Monge | RF | 22.051 | Boston Red Sox | Portland (AA) | Assigned to Portland (AA) |
| Jordan Montgomery | P | 24.193 | New York Yankees | Scranton/Wilkes-Barre (AAA) | Assigned to Scranton/Wilkes-Barre (AAA) |
| Jose Morales | P | 22.146 | Washington Nationals | Gulf Coast Nationals (Rk) | Assigned to Gulf Coast Nationals (Rk) |
| Dauri Moreta | p | 21.084 | Cincinnati Reds | Dayton (A) | Assigned to Dayton (A) |
| Max Murphy | OF | 24.233 | Minnesota Twins | Chattanooga (AA) | Assigned to Chattanooga (AA) |
| Tucker Nathans | IF | 28.244 | Baltimore Orioles | Norfolk (AAA) | Activated from disabled list |
| Chris O'Brien | C | 27.349 | Baltimore Orioles | Norfolk (AAA) | Assigned to Norfolk (AAA) |
| Sean O'Connell | P | 25.209 | Los Angeles Dodgers | Tulsa (AA) | Activated from disabled list |
| Mitchell Osnowitz | P | 26.006 | Boston Red Sox | Lowell (A-) | Assigned to Lowell (A-) |
| David Owen | p | 23.260 | San Francisco Giants | Sacramento (AAA) | Assigned to Sacramento (AAA) |
| Drake Owenby | p | 23.182 | Milwaukee Brewers | Wisconsin (A) | Assigned to Wisconsin (A) |
| Adonis Paula | 3B | 23.017 | Chicago Cubs | Myrtle Beach (A+) | Assigned to Myrtle Beach (A+) |
| Josh Pennington | p | 22.002 | Milwaukee Brewers | Wisconsin (A) | Assigned to Wisconsin (A) |
| Max Pentecost | C | 24.120 | Toronto Blue Jays | Dunedin (A+) | Assigned to Dunedin (A+) |
| Jurickson Profar | LF | 24.138 | Texas Rangers | Round Rock (AAA) | Assigned to Round Rock (AAA) |
| AJ Ramirez | 3b | 24.095 | San Francisco Giants | Sacramento (AAA) | Assigned to Sacramento (AAA) |
| Luis Ramirez | p | 21.224 | Houston Astros | Tri City (A-) | Assigned to Tri City (A-) |
| Milton Ramos | SS | 21.256 | Baltimore Orioles | Delmarva (A) | Assigned to Delmarva (A) |
| Artie Reyes | P | 25.093 | St. Louis Cardinals | Gulf Coast Cardinals (Rk) | Activated from disabled list |
| Sean Rodriguez | 1B-3B | 32.073 | Atlanta Braves | Gwinnett (AAA) | Assigned to Gwinnett (AAA) for rehab |
| Fabian Roman | P | 25.229 | Seattle Mariners | Everett (A-) | Assigned to Everett (A-) |
| Dan Runzler | RP | 32.100 | Pittsburgh Pirates | Indianapolis (AAA) | Activated from disabled list |
| Dalton Sawyer | p | 23.228 | Oakland Athletics | Stockton (A+) | Assigned to Stockton (A+) |
| Antonio Senzatela | P | 22.168 | Colorado Rockies | Albuquerque (AAA) | Assigned to Albuquerque (AAA) |
| Pedro Severino | C | 23.353 | Washington Nationals | Auburn (A-) | Assigned to Auburn (A-) for rehab |
| Heath Slatton | p | 23.294 | San Francisco Giants | San Jose (A+) | Assigned to San Jose (A+) |
| Albert Suarez | SP | 27.273 | San Francisco Giants | San Jose (A+) | Assigned to San Jose (A+) |
| Tyrone Taylor | OF | 23.167 | Milwaukee Brewers | Arizona Brewers (Rk) | Assigned to Arizona Brewers (Rk) |
| Jake Thomas | of | 23.352 | Toronto Blue Jays | Dunedin (A+) | Assigned to Dunedin (A+) |
| Cole Thompson | c | 23.088 | Arizona Diamondbacks | Kane County (A) | Assigned to Kane County (A) |
| Seth Varner | P | 25.163 | Cincinnati Reds | Arizona Reds (Rk) | Assigned to Arizona Reds (Rk) |
| Randy Vasquez | c | 21.117 | Houston Astros | Buies Creek (A+) | Assigned to Buies Creek (A+) |
| Andrew Vernon | p | 23.172 | Milwaukee Brewers | Wisconsin (A) | Assigned to Wisconsin (A) |
| Andre Wheeler | OF | 25.285 | Chicago White Sox | Arizona White Sox (Rk) | Activated from disabled list |
| Brant Whiting | C | 25.153 | Los Angeles Dodgers | Oklahoma City (AAA) | Activated from disabled list |
| DJ Wilson | of | 20.273 | Chicago Cubs | South Bend (A) | Assigned to South Bend (A) |
| Jordan Wren | of | 23.288 | Boston Red Sox | Lowell (A-) | Assigned to Lowell (A-) |
| Jonas Wyatt | p | 19.295 | Cleveland Indians | Arizona Indians (Rk) | Assigned to Arizona Indians (Rk) |
| Michael Ynoa | RP | 25.288 | Chicago White Sox | Charlotte (AAA) | Outrighted to minors |
| Jason Kipnis | 2B | 30.096 | Cleveland Indians | Cleveland Indians (MLB) | DL-10 Strained right hamstring |
| Jeff Locke | RP | 29.231 | Miami Marlins | Miami Marlins (MLB) | Outrighted to minors |
| Jerad Eickhoff | SP | 27.006 | Philadelphia Phillies | Philadelphia Phillies (MLB) | Activated from DL |
| Arcenio Leon | P | 30.289 | Detroit Tigers | Toledo (AAA) | DL-7 Injured |
| Casey Coleman | P | 30.005 | | | Released by Astros |
| Daniel Bard | RP | 32.013 | New York Mets | St. Lucie (A+) | DL-7 Injured |
| Jarrett Grube | P | 35.245 | Cleveland Indians | Columbus (AAA) | DL-7 Injured |
| Matt Stites | RP | 27.041 | | | Released by Diamondbacks |
| Robert Whalen | P | 23.158 | Seattle Mariners | Tacoma (AAA) | DL-7 Injured |
| Ronald Herrera | P | 22.066 | New York Yankees | Scranton/Wilkes-Barre (AAA) | DL-7 Injured |
| Brian Holmes | P | 26.159 | | | Released by Astros |
| Jalen Beeks | P | 23.363 | Boston Red Sox | Pawtucket (AAA) | Placed on temporary inactive list |
| Jimmy Reyes | P | 28.123 | Texas Rangers | Round Rock (AAA) | Placed on temporary inactive list |
| Mike Ford | P | 25.004 | New York Yankees | Scranton/Wilkes-Barre (AAA) | DL-7 Injured |
| Ryan Yarbrough | P | 25.190 | Tampa Bay Rays | Durham (AAA) | Placed on temporary inactive list |
| Trent Woodward | C | 25.155 | Houston Astros | Corpus Christi (AA) | DL-7 Injured |
| Brendan Rodgers | ss | 20.333 | Colorado Rockies | Hartford (AA) | Placed on temporary inactive list |
| Dickie Thon | SS | 25.235 | | | Released by Cardinals |
| Erick Matta | c | 23.090 | Texas Rangers | Down East (A+) | DL-7 Injured |
| Justus Sheffield | P | 21.056 | New York Yankees | Trenton (AA) | DL-7 Injured |
| Kyle Tucker | of | 20.172 | Houston Astros | Corpus Christi (AA) | Placed on temporary inactive list |
| Michael Kopech | P | 21.069 | Chicago White Sox | Birmingham (AA) | Placed on temporary inactive list |
| Arturo Lara | ss | 26.136 | Texas Rangers | Down East (A+) | DL-7 Injured |
| Corey Ray | of | 22.289 | Milwaukee Brewers | Carolina (A+) | Placed on temporary inactive list |
| Drew Harrington | p | 22.100 | Atlanta Braves | Florida (A+) | DL-7 Injured |
| Johan Cruz | SS | 21.274 | Chicago White Sox | Winston-Salem (A+) | DL-7 Injured |
| Jon Duplantier | p | 22.362 | Arizona Diamondbacks | Visalia (A+) | Placed on temporary inactive list |
| Jordan Humphreys | p | 21.027 | New York Mets | St. Lucie (A+) | DL-7 Injured |
| Matt Smoral | P | 23.112 | Texas Rangers | Hickory (A) | DL-7 Injured |
| Sam Held | p | 22.318 | Washington Nationals | Hagerstown (A) | DL-7 Injured |
| Tyler Sullivan | of | 24.229 | | | Released by White Sox |
| Victor Robles | of | 20.050 | Washington Nationals | Potomac (A+) | Placed on temporary inactive list |
| Zack Collins | c | 22.152 | Chicago White Sox | Winston-Salem (A+) | Placed on temporary inactive list |
| JD Busfield | p | 22.064 | Tampa Bay Rays | Bowling Green (A) | DL-7 Injured |
| Jose Almonte | OF | 20.302 | Texas Rangers | Hickory (A) | DL-7 Injured |
| Luis Ledo | p | 22.041 | Chicago White Sox | Great Falls (Rk) | DL-7 Injured |
| NIck Wells | P | 21.138 | Seattle Mariners | Clinton (A) | DL-7 Injured |
| Lance Jones | of | 24.240 | | | Announced retirement |
| Alian Silva | 2b | 23.040 | | | Released by Nationals |
| Nate Coronado | if | 25.033 | | | Released by Rockies |
| Christian Broussard | p | 20.260 | Minnesota Twins | Elizabethton (Rk) | DL-7 Injured |
| Curtiss Pomeroy | p | 24.064 | | | Released by Yankees |
| Josh Roberson | p | 21.057 | Miami Marlins | Gulf Coast Marlins (Rk) | DL-60 Injured |
| Meliton Reyes | p | 19.342 | Toronto Blue Jays | Gulf Coast Blue Jays (Rk) | DL-60 Injured |
| Mike McCann | c | 21.363 | | | Released by Royals |
| Roberto Medina | c | 19.287 | | | Released by Nationals |
| Anthony Gose | CF | 26.332 | Detroit Tigers | Lakeland (A+) | DL-7 Injured |
| Blake Swihart | C | 25.096 | Boston Red Sox | Pawtucket (AAA) | DL-7 Injured |
| Conor Mullee | RP | 29.134 | | | Released by Cubs |
| Matt Tracy | P | 28.224 | Minnesota Twins | Chattanooga (AA) | DL-7 Injured |
| Tyler Wagner | IF | 26.165 | Texas Rangers | Round Rock (AAA) | DL-7 Injured |
| Andury Acevedo | P | 26.319 | | | Released by Cubs |
| Leonardo Reginatto | 3B | 27.089 | Minnesota Twins | Rochester (AAA) | DL-7 Injured |
| Rene Melendez | C | 22.169 | | | Released by Giants |
| Zane Evans | C-P | 25.222 | | | Announced retirement |
| Josh Rapacz | C | 26.363 | Tampa Bay Rays | Charlotte (A+) | DL-7 Injured |
| Miles Chambers | p | 23.259 | New York Yankees | Gulf Coast Yankees (Rk) | DL-60 Injured |
| Kramer Robertson | 2b | 22.291 | St. Louis Cardinals | Peoria (A) | Signed out of draft (LSU) |
| Austen Wade | of | 21.142 | Cleveland Indians | Mahoning Valley (A-) | Signed out of draft (TCU) |
| Brandon Hughes | of | 21.220 | Chicago Cubs | Eugene (A-) | Signed out of draft (Michigan State) |
| Jared Young | 2b | 21.365 | Chicago Cubs | Eugene (A-) | Signed out of draft (Old Dominion) |
| Mike Papierski | c | 21.133 | Houston Astros | Tri City (A-) | Signed out of draft (LSU) |
| Mike Rivera | c | 21.209 | Cleveland Indians | Mahoning Valley (A-) | Signed out of draft (Florida) |
| Alex Dunlap | c | 22.275 | Washington Nationals | Gulf Coast Nationals (Rk) | Signed out of draft (Stanford) |
| Cam Warner | if | 23.126 | Detroit Tigers | Gulf Coast Tigers (East) (Rk) | Signed out of draft (TCU) |
| Elliott Barzilli | ss | 22.066 | Miami Marlins | Gulf Coast Marlins (Rk) | Signed out of draft (TCU) |
| Eric Senior | of | 19.282 | Washington Nationals | Gulf Coast Nationals (Rk) | Signed out of draft (Midland) |
| Evan Skoug | c | 21.261 | Chicago White Sox | Arizona White Sox (Rk) | Signed out of draft (TCU) |
| Justin Bellinger | 1b | 21.325 | Cincinnati Reds | Arizona Reds (Rk) | Signed out of draft (Duke) |
| Justin Connell | of | 18.119 | Washington Nationals | Gulf Coast Nationals (Rk) | Signed out of draft (Florida HS) |
| K.J. Harrison | 1b | 20.331 | Milwaukee Brewers | Helena (Rk) | Signed out of draft (Oregon State) |
| Logan Taylor | of | 23.017 | Chicago White Sox | Arizona White Sox (Rk) | Signed out of draft (Louisville) |
| Nick Snyder | p | 21.272 | Texas Rangers | Arizona Rangers (Rk) | Signed out of draft (Indian River State) |
| Phil Caulfield | 2b | 22.190 | Washington Nationals | Gulf Coast Nationals (Rk) | Signed out of draft (Loyola Marymount) |
| Ricky Vanasco | p | 18.268 | Texas Rangers | Arizona Rangers (Rk) | Signed out of draft (Florida HS) |
| Will Gaddis | p | 21.118 | Colorado Rockies | Grand Junction (Rk) | Signed out of draft (Furman) |
| Tom Colletti | p | 22.016 | San Diego Padres | Arizona Padres (Rk) | Signed as undrafted free agent (Ohio) |
| Aaron Myers | p | 23.309 | Baltimore Orioles | Delmarva (A) | Traded from Brewers to Orioles for cash considerations |
