| Audie Afenir | c | 25.077 | New York Yankees | Tampa (A+) | Assigned to Tampa (A+) |
| Osmel Aguila | of | 27.288 | Philadelphia Phillies | Reading (AA) | Assigned to Reading (AA) |
| Yordy Alejo | p | 23.170 | Oakland Athletics | Beloit (A) | Assigned to Beloit (A) |
| Rogelio Armenteros | p | 22.306 | Houston Astros | Corpus Christi (AA) | Assigned to Corpus Christi (AA) |
| Danny Bethea | C | 27.091 | Boston Red Sox | Portland (AA) | Activated from disabled list |
| Christoph Bono | of | 24.208 | San Francisco Giants | Augusta (A) | Activated from disabled list |
| Geoffrey Bramblett | p | 22.006 | Kansas City Royals | Lexington (A) | Assigned to Lexington (A) |
| Mauricio Cabrera | RP | 23.222 | Atlanta Braves | Gwinnett (AAA) | Assigned to Gwinnett (AAA) for rehab |
| Ranfi Casimiro | P | 24.290 | Philadelphia Phillies | Clearwater (A+) | Assigned to Clearwater (A+) |
| Jarred Cosart | SP | 26.342 | San Diego Padres | Lake Elsinore (A+) | Assigned to Lake Elsinore (A+) for rehab |
| Carlos Diaz | P | 23.165 | San Francisco Giants | San Jose (A+) | Activated from disabled list |
| Nick Dini | c | 23.279 | Kansas City Royals | Lexington (A) | Reinstated to active roster |
| Chris Dominguez | 1b | 30.161 | Chicago Cubs | Iowa (AAA) | Assigned to Iowa (AAA) |
| Logan Forsythe | 2B-3B | 30.108 | Los Angeles Dodgers | Rancho Cucamonga (A+) | Assigned to Rancho Cucamonga (A+) for rehab |
| Ryan Garton | RP | 27.148 | Tampa Bay Rays | Durham (AAA) | Assigned to Durham (AAA) |
| Wil Gilbert | p | 23.082 | Oakland Athletics | Stockton (A+) | Assigned to Stockton (A+) |
| Zack Godley | RP | 27.011 | Arizona Diamondbacks | Reno (AAA) | Assigned to Reno (AAA) |
| Ryan Hartman | p | 23.011 | Houston Astros | Quad Cities (A) | Assigned to Quad Cities (A) |
| Kevin Herget | P | 26.029 | St. Louis Cardinals | Springfield (AA) | Assigned to Springfield (AA) |
| Carlos Hernandez | P | 23.006 | Arizona Diamondbacks | Kane County (A) | Assigned to Kane County (A) |
| Jonathan Hernandez | p | 20.300 | Texas Rangers | Hickory (A) | Reinstated to active roster |
| Carlos Herrera | ss | 20.221 | Colorado Rockies | Asheville (A) | Assigned to Asheville (A) |
| John Hicks | 1B | 27.244 | Detroit Tigers | Toledo (AAA) | Assigned to Toledo (AAA) |
| Colt Hynes | RP | 31.308 | Los Angeles Dodgers | Tulsa (AA) | Assigned to Tulsa (AA) |
| Joshua James | P | 24.055 | Houston Astros | Corpus Christi (AA) | Assigned to Corpus Christi (AA) |
| Gosuke Katoh | 2B | 22.206 | New York Yankees | Tampa (A+) | Assigned to Tampa (A+) |
| Stephen Kohlscheen | P | 28.224 | Milwaukee Brewers | Colorado Springs (AAA) | Activated from disabled list |
| AJ Ladwig | P | 24.129 | Detroit Tigers | Toledo (AAA) | Assigned to Toledo (AAA) |
| Deiner Lopez | | 22.337 | Boston Red Sox | Portland (AA) | Assigned to Portland (AA) |
| Nick Lovullo | ss | 23.152 | Boston Red Sox | Salem (A+) | Assigned to Salem (A+) |
| Cory Luebke | RP | 32.059 | Chicago White Sox | Charlotte (AAA) | Assigned to Charlotte (AAA) |
| Luis Marte | SS | 23.138 | Texas Rangers | Frisco (AA) | Assigned to Frisco (AA) |
| Mark Mathias | 2b | 22.273 | Cleveland Indians | Akron (AA) | Activated from disabled list |
| Jacob May | CF | 25.100 | Chicago White Sox | Charlotte (AAA) | Assigned to Charlotte (AAA) |
| Seth Mejias-Brean | IF | 26.027 | Seattle Mariners | Tacoma (AAA) | Traded from Reds to Mariners |
| Luis Mendez | 2B-SS | 24.121 | Texas Rangers | Down East (A+) | Assigned to Down East (A+) |
| Heiker Meneses | SS-2B | 25.306 | Boston Red Sox | Pawtucket (AAA) | Assigned to Pawtucket (AAA) |
| Melvin Mercedes | SS | 25.110 | Oakland Athletics | Midland (AA) | Assigned to Midland (AA) |
| Bryan Mitchell | RP | 26.013 | New York Yankees | Scranton/Wilkes-Barre (AAA) | Assigned to Scranton/Wilkes-Barre (AAA) |
| Ryan Moseley | p | 22.208 | Los Angeles Dodgers | Rancho Cucamonga (A+) | Assigned to Rancho Cucamonga (A+) |
| Manny Olloque | 3B | 20.356 | Kansas City Royals | Lexington (A) | Assigned to Lexington (A) |
| Danny Ortiz | RF-LF | 27.117 | Pittsburgh Pirates | Indianapolis (AAA) | Assigned to Indianapolis (AAA) |
| Paul Paez | P | 25.003 | Seattle Mariners | Tacoma (AAA) | Assigned to Tacoma (AAA) |
| Matthew Page | OF | 25.193 | Washington Nationals | Potomac (A+) | Assigned to Potomac (A+) |
| Brallan Perez | 2B | 21.096 | Texas Rangers | Hickory (A) | Assigned to Hickory (A) |
| Julio Perez | p | 25.107 | Arizona Diamondbacks | Kane County (A) | Assigned to Kane County (A) |
| Julio Pinto | P | 21.166 | Kansas City Royals | Lexington (A) | Reinstated to active roster |
| Jurickson Profar | LF | 24.071 | Texas Rangers | Round Rock (AAA) | Assigned to Round Rock (AAA) |
| Isaias Quiroz | C | 20.192 | Texas Rangers | Hickory (A) | Assigned to Hickory (A) |
| Lane Ratliff | P | 22.041 | Seattle Mariners | Tacoma (AAA) | Assigned to Tacoma (AAA) |
| Joe Ross | SP | 23.346 | Washington Nationals | Syracuse (AAA) | Assigned to Syracuse (AAA) |
| Jagger Rusconi | of | 20.288 | Boston Red Sox | Greenville (A) | Assigned to Greenville (A) |
| Gary Sanchez | C | 24.151 | New York Yankees | Scranton/Wilkes-Barre (AAA) | Assigned to Scranton/Wilkes-Barre (AAA) for rehab |
| Tyler Selesky | if | 23.208 | San Diego Padres | Fort Wayne (A) | Assigned to Fort Wayne (A) |
| Jake Shull | p | 23.006 | Detroit Tigers | Lakeland (A+) | Assigned to Lakeland (A+) |
| Jake Simon | p | 20.101 | New York Mets | Columbia (A) | Assigned to Columbia (A) |
| Andrew Stevenson | of | 22.335 | Washington Nationals | Syracuse (AAA) | Assigned to Syracuse (AAA) |
| Aneury Tavarez | 2B | 25.018 | Boston Red Sox | Pawtucket (AAA) | Assigned to Pawtucket (AAA) |
| Logan Taylor | P | 25.141 | New York Mets | Las Vegas (AAA) | Assigned to Las Vegas (AAA) |
| Andrew Tomasovich | p | 23.332 | Oakland Athletics | Stockton (A+) | Assigned to Stockton (A+) |
| Jose Valdez | RP | 27.062 | Los Angeles Angels | Salt Lake (AAA) | Assigned to Salt Lake (AAA) |
| Scott Van Slyke | LF | 30.282 | Los Angeles Dodgers | Oklahoma City (AAA) | Assigned to Oklahoma City (AAA) |
| Ross Vance | p | 25.147 | St. Louis Cardinals | Palm Beach (A+) | Assigned to Palm Beach (A+) |
| Logan Verrett | RP | 26.317 | Baltimore Orioles | Norfolk (AAA) | Assigned to Norfolk (AAA) |
| Kender Villegas | P | 23.328 | Toronto Blue Jays | New Hampshire (AA) | Assigned to New Hampshire (AA) |
| Tyler Viza | P | 22.193 | Philadelphia Phillies | Reading (AA) | Assigned to Reading (AA) |
| Dan Vogelbach | 1B | 24.136 | Seattle Mariners | Tacoma (AAA) | Assigned to Tacoma (AAA) |
| Luke Weaver | SP | 23.254 | St. Louis Cardinals | Memphis (AAA) | Activated from disabled list |
| Jonah Wesely | P | 22.145 | Los Angeles Angels | Burlington (A) | Activated from disabled list |
| Hector Santiago | SP | 29.138 | Minnesota Twins | Minnesota Twins (MLB) | Reinstated from Bereavement list |
| Damien Magnifico | RP | 25.344 | Baltimore Orioles | Norfolk (AAA) | Designated for Assignment |
| Casey Coleman | P | 29.304 | Houston Astros | Houston Astros (MLB) | Signed to Minor League Contract |
| Zach Stewart | P | 30.216 | | | Released by Orioles |
| Michael Choice | RF | 27.173 | | | Released by Orioles |
| Shawn O'Malley | RF-3B | 29.126 | Seattle Mariners | Seattle Mariners (MLB) | Transferred to 60-day DL |
| Jean Machi | RP | 34.090 | Seattle Mariners | Seattle Mariners (MLB) | Contract purchased from minors |
| Emilio Pagan | P | 25.361 | Seattle Mariners | Seattle Mariners (MLB) | Contract purchased from minors |
| Casey Fien | RP | 33.194 | Seattle Mariners | Seattle Mariners (MLB) | Designated for Assignment |
| Luis Valbuena | 3B | 31.153 | Los Angeles Angels | Los Angeles Angels (MLB) | Activated from DL |
| Francisco Pena | C | 27.202 | Baltimore Orioles | Baltimore Orioles (MLB) | Contract purchased from minors |
| Welington Castillo | C | 30.008 | Baltimore Orioles | Baltimore Orioles (MLB) | DL-10 Shoulder tendinitis |
| Franklin Gutierrez | LF | 34.070 | Los Angeles Dodgers | Los Angeles Dodgers (MLB) | Activated from DL |
| Josh Osich | RP | 28.241 | San Francisco Giants | San Francisco Giants (MLB) | Recalled from Sacramento (AAA) |
| Shawn Armstrong | RP | 26.233 | Cleveland Indians | Cleveland Indians (MLB) | Recalled from Columbus (AAA) |
| Zack Britton | CL | 29.132 | Baltimore Orioles | Baltimore Orioles (MLB) | Activated from DL |
| Austin Jackson | CF | 30.090 | Cleveland Indians | Cleveland Indians (MLB) | DL-10 Hyperextended left big toe |
| Rob Refsnyder | LF | 26.037 | New York Yankees | New York Yankees (MLB) | Recalled from Scranton/Wilkes-Barre (AAA) |
| Greg Bird | 1B | 24.174 | New York Yankees | New York Yankees (MLB) | DL-10 Right ankle bruise |
| Miguel Cabrera | 1B | 34.014 | Detroit Tigers | Detroit Tigers (MLB) | Activated from DL |
| Shane Peterson | DH-LF | 29.081 | Tampa Bay Rays | Tampa Bay Rays (MLB) | Designated for Assignment |
| Colby Rasmus | LF | 30.264 | Tampa Bay Rays | Tampa Bay Rays (MLB) | Activated from DL |
| Sam Tuivailala | RP | 24.195 | St. Louis Cardinals | St. Louis Cardinals (MLB) | Recalled from Memphis (AAA) |
| Tyler Lyons | RP | 29.071 | St. Louis Cardinals | St. Louis Cardinals (MLB) | DL-10 Right intercostal strain |
| Rajai Davis | CF | 36.195 | Oakland Athletics | Oakland Athletics (MLB) | Activated from DL |
| AJ Cole | SP | 25.118 | Washington Nationals | Washington Nationals (MLB) | Recalled from Syracuse (AAA) (finished serving last season's suspension for first 3 days) |
| Willy Garcia | LF | 24.240 | Chicago White Sox | Chicago White Sox (MLB) | Recalled from Charlotte (AAA) |
| Chasen Shreve | RP | 26.294 | New York Yankees | New York Yankees (MLB) | Recalled from Scranton/Wilkes-Barre (AAA) |
| Adrian Sampson | P | 25.208 | Texas Rangers | Round Rock (AAA) | DL-60 Injured |
| Gordon Beckham | 3B | 30.228 | Seattle Mariners | Tacoma (AAA) | DL-7 Injured |
| Jake Esch | RP | 27.036 | San Diego Padres | San Antonio (AA) | DL-7 Injured |
| James Jones | RF | 28.220 | Texas Rangers | Round Rock (AAA) | DL-60 Injured |
| Carlos Diaz | ss | 24.168 | Kansas City Royals | Idaho Falls (Rk) | Assigned to Idaho Falls (Rk) |
| Clayton Blackburn | P | 24.116 | Texas Rangers | Round Rock (AAA) | DL-7 Injured |
| Hunter Adkins | P | 26.224 | Miami Marlins | Jacksonville (AA) | DL-7 Injured |
| Jose Rosario | SS-2B | 25.155 | Boston Red Sox | Portland (AA) | Placed on temporary inactive list |
| Nick Routt | P | 26.247 | Cincinnati Reds | Louisville (AAA) | Placed on temporary inactive list |
| Ryan Thompson | P | 24.310 | Houston Astros | Fresno (AAA) | DL-7 Injured |
| Trace Tam Sing | 2B | 25.147 | | | Released by Pirates |
| David Berg | p | 24.035 | Chicago Cubs | Tennessee (AA) | DL-7 Injured |
| Jeff McNeil | IF-OF | 25.024 | New York Mets | St. Lucie (A+) | DL-7 Injured |
| Rashad Crawford | OF | 23.199 | New York Yankees | Trenton (AA) | DL-7 Injured |
| Wes Helsabeck | p | 24.299 | Los Angeles Dodgers | Rancho Cucamonga (A+) | DL-7 Injured |
| Chris Mathewson | p | 20.341 | Los Angeles Dodgers | Los Angeles Dodgers (MLB) | Assigned to extended spring training |
| Colin Poche | p | 23.105 | Arizona Diamondbacks | Arizona Diamondbacks (MLB) | Assigned to extended spring training |
| D.K. Carey | OF | 25.170 | Washington Nationals | Potomac (A+) | DL-7 Injured |
| Heath Holder | p | 24.252 | Colorado Rockies | Lancaster (A+) | Placed on temporary inactive list |
| Jared Robinson | P | 22.163 | Cleveland Indians | Lynchburg (A+) | DL-7 Injured |
| Jomar Reyes | 3B | 20.071 | Baltimore Orioles | Frederick (A+) | DL-7 Injured |
| Jon Olczak | p | 23.169 | Milwaukee Brewers | Carolina (A+) | DL-7 Injured |
| Luke Dykstra | 2B | 21.177 | St. Louis Cardinals | Palm Beach (A+) | DL-7 Injured |
| Zack Hartman | p | 25.122 | Los Angeles Dodgers | Rancho Cucamonga (A+) | DL-7 Injured |
| Zack Littell | P | 21.210 | New York Yankees | New York Yankees (MLB) | Assigned to extended spring training |
| Casey Thomas | 2b | 24.047 | | | Deceased |
| Julian Villamar | p | 23.009 | | | Released by Pirates |
