| Jhonniel Alvarez | if | 23.198 | Texas Rangers | Round Rock (AAA) | Assigned to Round Rock (AAA) |
| Angelo Amendolare | 2b | 23.273 | Los Angeles Angels | Inland Empire (A+) | Assigned to Inland Empire (A+) |
| Caleb Baragar | p | 22.145 | San Francisco Giants | San Jose (A+) | Assigned to San Jose (A+) |
| Luis Alexander Basabe | OF | 20.006 | Boston Red Sox | Salem (A+) | Assigned to Salem (A+) |
| Quintin Berry | lf | 31.284 | Toronto Blue Jays | Buffalo (AAA) | Signed to Minor League Contract |
| Julio Borbon | CF | 30.193 | Baltimore Orioles | Bowie (AA) | Assigned to Bowie (AA) |
| Jose Briceno | C | 23.347 | Los Angeles Angels | Salt Lake (AAA) | Assigned to Salt Lake (AAA) |
| Aaron Bummer | P | 22.345 | Chicago White Sox | Charlotte (AAA) | Assigned to Charlotte (AAA) |
| Daniel Carbonell | OF | 25.156 | San Francisco Giants | Sacramento (AAA) | Assigned to Sacramento (AAA) |
| Anthony Caronia | IF-OF | 25.102 | Baltimore Orioles | Frederick (A+) | Activated from disabled list |
| Xorge Carrillo | C | 27.142 | New York Mets | Las Vegas (AAA) | Assigned to Las Vegas (AAA) |
| Willi Castro | SS | 19.130 | Cleveland Indians | Lynchburg (A+) | Assigned to Lynchburg (A+) |
| Erlin Cerda | 3b | 22.119 | Cleveland Indians | Lake County (A) | Assigned to Lake County (A) |
| Colton Davis | p | 22.239 | Minnesota Twins | Cedar Rapids (A) | Assigned to Cedar Rapids (A) |
| Allan De San Miguel | C | 28.213 | Kansas City Royals | Omaha (AAA) | Activated from disabled list |
| Tim Dillard | P | 33.044 | Milwaukee Brewers | Colorado Springs (AAA) | Activated from disabled list |
| Chris Dula | P | 24.026 | Texas Rangers | Hickory (A) | Assigned to Hickory (A) |
| Miguel Eladio | ss | 20.114 | Cleveland Indians | Mahoning Valley (A-) | Assigned to Mahoning Valley (A-) |
| Ethan Elias | P | 23.127 | Arizona Diamondbacks | Visalia (A+) | Assigned to Visalia (A+) |
| Tanner English | OF | 23.174 | Minnesota Twins | Rochester (AAA) | Assigned to Rochester (AAA) |
| Gregorix Estevez | p | 22.142 | New York Mets | Brooklyn (A-) | Assigned to Brooklyn (A-) |
| Brady Feigl | P | 25.248 | Atlanta Braves | Gwinnett (AAA) | Activated from disabled list |
| Estevan Florial | of | 18.280 | New York Yankees | Charleston (sc) (A) | Assigned to Charleston (sc) (A) |
| Kelvin Franco | p | 21.307 | Colorado Rockies | Boise (A-) | Activated from disabled list |
| Omar Garcia | CF | 23.031 | Milwaukee Brewers | Biloxi (AA) | Activated from disabled list |
| Steve Geltz | RP | 28.305 | Tampa Bay Rays | Durham (AAA) | Assigned to Durham (AAA) |
| Alfredo Gonzalez | C | 24.050 | Chicago White Sox | Charlotte (AAA) | Assigned to Charlotte (AAA) |
| Oscar Gonzalez | of | 18.234 | Cleveland Indians | Mahoning Valley (A-) | Assigned to Mahoning Valley (A-) |
| Grayson Greiner | C | 23.325 | Detroit Tigers | Toledo (AAA) | Assigned to Toledo (AAA) |
| Hunter Harvey | P | 21.266 | Baltimore Orioles | Aberdeen (A-) | Assigned to Aberdeen (A-) |
| Tyler Herron | P | 30.027 | New York Mets | Las Vegas (AAA) | Assigned to Las Vegas (AAA) |
| Chad Hinshaw | OF | 25.356 | Los Angeles Angels | Orem (Rk) | Assigned to Orem (Rk) |
| Henry Hirsch | P | 23.337 | Pittsburgh Pirates | Altoona (AA) | Assigned to Altoona (AA) |
| Jordan Humphreys | p | 20.082 | New York Mets | Brooklyn (A-) | Assigned to Brooklyn (A-) |
| David Jacob | 1b | 21.074 | Toronto Blue Jays | Vancouver (A-) | Assigned to Vancouver (A-) |
| Chris Jensen | P | 25.336 | Oakland Athletics | Nashville (AAA) | Assigned to Nashville (AAA) |
| Domingo Jimenez | p | 23.003 | Cleveland Indians | Mahoning Valley (A-) | Assigned to Mahoning Valley (A-) |
| Jeff Johnson | P | 26.204 | Cleveland Indians | Columbus (AAA) | Activated from disabled list |
| Christopher Jones | P | 27.347 | Los Angeles Angels | Salt Lake (AAA) | Activated from disabled list |
| Reece Karalus | p | 22.079 | Tampa Bay Rays | Bowling Green (A) | Assigned to Bowling Green (A) |
| Trevor Kelley | p | 22.316 | Boston Red Sox | Greenville (A) | Activated from disabled list |
| Steve Kent | p | 27.116 | Atlanta Braves | Gwinnett (AAA) | Assigned to Gwinnett (AAA) |
| Sean Keselica | p | 23.079 | Pittsburgh Pirates | Bradenton (A+) | Assigned to Bradenton (A+) |
| Ricky Knapp | P | 24.104 | New York Mets | Las Vegas (AAA) | Assigned to Las Vegas (AAA) |
| Ben Krauth | p | 22.175 | Cleveland Indians | Lake County (A) | Assigned to Lake County (A) |
| Eric Lauer | p | 21.090 | San Diego Padres | Fort Wayne (A) | Assigned to Fort Wayne (A) |
| Sam LeCure | RP | 32.120 | Los Angeles Dodgers | Oklahoma City (AAA) | Activated from disabled list |
| Leandro Linares | P | 22.217 | Cleveland Indians | Lynchburg (A+) | Assigned to Lynchburg (A+) |
| Logan Lombana | p | 22.046 | Minnesota Twins | Fort Myers (A+) | Assigned to Fort Myers (A+) |
| Jack Lopez | SS | 23.259 | Kansas City Royals | Northwest Arkansas (AA) | Activated from disabled list |
| Junior Lopez | P | 25.066 | Pittsburgh Pirates | Altoona (AA) | Assigned to Altoona (AA) |
| Simeon Lucas | C | 20.207 | Cleveland Indians | Mahoning Valley (A-) | Assigned to Mahoning Valley (A-) |
| Joey Lucchesi | p | 23.087 | San Diego Padres | Fort Wayne (A) | Assigned to Fort Wayne (A) |
| Mark Mathias | 2b | 22.030 | Cleveland Indians | Akron (AA) | Assigned to Akron (AA) |
| Jerry McClanahan | c | 24.082 | Baltimore Orioles | Frederick (A+) | Assigned to Frederick (A+) |
| Stephen McGee | C | 25.206 | Miami Marlins | New Orleans (AAA) | Signed to Minor League Contract |
| Zeke McGranahan | P | 25.241 | Baltimore Orioles | Gulf Coast Orioles (Rk) | Assigned to Gulf Coast Orioles (Rk) |
| Miguel Mejia | p | 28.226 | Chicago Cubs | Iowa (AAA) | Activated from disabled list |
| Luis Mendez | 2B-SS | 23.243 | Texas Rangers | Round Rock (AAA) | Activated from disabled list |
| Narciso Mesa | CF | 24.290 | Washington Nationals | Potomac (A+) | Assigned to Potomac (A+) |
| Jordan Milbrath | P | 25.031 | Cleveland Indians | Akron (AA) | Assigned to Akron (AA) |
| Alex Monsalve | C | 24.132 | Cleveland Indians | Akron (AA) | Assigned to Akron (AA) |
| Chan Moon | SS | 25.162 | Houston Astros | Fresno (AAA) | Activated from disabled list |
| A.J. Morris | P | 29.274 | Cincinnati Reds | Louisville (AAA) | Assigned to Louisville (AAA) for rehab |
| Clayton Mortensen | RP | 31.144 | Kansas City Royals | Omaha (AAA) | Activated from disabled list |
| D.J. Myers | p | 21.251 | San Francisco Giants | Sacramento (AAA) | Assigned to Sacramento (AAA) |
| Nick Neumann | P | 25.128 | Pittsburgh Pirates | Bradenton (A+) | Activated from disabled list |
| Garrett Nuss | P | 23.139 | Los Angeles Angels | Inland Empire (A+) | Reinstated to active roster |
| Tyler Ogle | C | 26.023 | Los Angeles Dodgers | Oklahoma City (AAA) | Assigned to Oklahoma City (AAA) |
| Tyler Olson | P | 26.334 | Cleveland Indians | Columbus (AAA) | Activated from disabled list |
| Spencer Patton | RP | 28.194 | Chicago Cubs | Iowa (AAA) | Assigned to Iowa (AAA) |
| Mark Payton | OF | 24.269 | New York Yankees | Scranton/Wilkes-Barre (AAA) | Assigned to Scranton/Wilkes-Barre (AAA) |
| Tyson Perez | P | 26.248 | Houston Astros | Fresno (AAA) | Assigned to Fresno (AAA) |
| Tyrone Perry | 1b | 20.313 | Milwaukee Brewers | Brevard County (A+) | Assigned to Brevard County (A+) |
| Zach Phillips | P | 29.345 | Pittsburgh Pirates | Indianapolis (AAA) | Assigned to Indianapolis (AAA) |
| Cody Poteet | p | 22.033 | Miami Marlins | Greensboro (A) | Activated from disabled list |
| Heath Quinn | of | 21.086 | San Francisco Giants | San Jose (A+) | Assigned to San Jose (A+) |
| Logan Ratledge | ss | 24.043 | Pittsburgh Pirates | Bradenton (A+) | Assigned to Bradenton (A+) |
| Webster Rivas | C | 26.024 | Los Angeles Angels | Inland Empire (A+) | Activated from disabled list |
| C.J. Robinson | P | 23.113 | Miami Marlins | Jupiter (A+) | Assigned to Jupiter (A+) |
| Rock Rucker | p | 23.161 | Cincinnati Reds | Daytona (A+) | Assigned to Daytona (A+) |
| Wynston Sawyer | C | 24.292 | Baltimore Orioles | Bowie (AA) | Assigned to Bowie (AA) |
| Bo Schultz | RP | 30.341 | Toronto Blue Jays | Buffalo (AAA) | Assigned to Buffalo (AAA) |
| Joe Shaw | p | 22.255 | New York Mets | Binghamton (AA) | Assigned to Binghamton (AA) |
| Luis Silva | p | 19.288 | New York Mets | Columbia (A) | Assigned to Columbia (A) |
| Dalbert Siri | p | 21.044 | Cleveland Indians | Mahoning Valley (A-) | Assigned to Mahoning Valley (A-) |
| Chance Sisco | C | 21.189 | Baltimore Orioles | Norfolk (AAA) | Assigned to Norfolk (AAA) |
| Dan Slania | P | 24.100 | San Francisco Giants | Sacramento (AAA) | Assigned to Sacramento (AAA) |
| Juan Soto | of | 17.311 | Washington Nationals | Auburn (A-) | Assigned to Auburn (A-) |
| David Speer | P | 24.018 | Cleveland Indians | Akron (AA) | Assigned to Akron (AA) |
| Owen Spiwak | c | 21.101 | Toronto Blue Jays | Vancouver (A-) | Assigned to Vancouver (A-) |
| Michael Strentz | C | 24.296 | Los Angeles Angels | Arkansas (AA) | Assigned to Arkansas (AA) |
| Nick Vespi | p | 20.327 | Baltimore Orioles | Aberdeen (A-) | Assigned to Aberdeen (A-) |
| Jose Vinicio | SS | 23.053 | Boston Red Sox | Pawtucket (AAA) | Reinstated to active roster |
| David Whitehead | P | 24.133 | Pittsburgh Pirates | West Virginia (A-) | Assigned to West Virginia (A-) |
| Ty Kelly | LF | 28.043 | New York Mets | New York Mets (MLB) | Recalled from Las Vegas (AAA) |
| Matt Dermody | RP | 26.059 | Toronto Blue Jays | Toronto Blue Jays (MLB) | Contract purchased from minors |
| Jake Buchanan | SP | 26.342 | Chicago Cubs | Chicago Cubs (MLB) | Contract purchased from minors |
| Chris Coghlan | 1B | 31.075 | Chicago Cubs | Chicago Cubs (MLB) | Activated from DL |
| Brett Nicholas | 1B | 28.045 | Texas Rangers | Texas Rangers (MLB) | Recalled from Round Rock (AAA) |
| Yohander Mendez | RP | 21.227 | Texas Rangers | Texas Rangers (MLB) | Recalled from Round Rock (AAA) |
| Nick Martinez | RP | 26.027 | Texas Rangers | Texas Rangers (MLB) | Recalled from Round Rock (AAA) |
| Hanser Alberto | 3B | 23.319 | Texas Rangers | Texas Rangers (MLB) | Recalled from Round Rock (AAA) |
| Michael Conforto | CF-LF | 23.184 | New York Mets | New York Mets (MLB) | Recalled from Las Vegas (AAA) |
| Joe Smith | RP | 32.163 | Chicago Cubs | Chicago Cubs (MLB) | Activated from DL |
| Destin Hood | RF | 26.151 | Miami Marlins | Miami Marlins (MLB) | Contract purchased from minors |
| Tomas Telis | C | 25.075 | Miami Marlins | Miami Marlins (MLB) | Recalled from New Orleans (AAA) |
| Brian Ellington | RP | 26.028 | Miami Marlins | Miami Marlins (MLB) | Recalled from New Orleans (AAA) |
| Nefi Ogando | RP | 27.090 | Miami Marlins | Miami Marlins (MLB) | Recalled from New Orleans (AAA) |
| Raudel Lazo | RP | 27.142 | Miami Marlins | New Orleans (AAA) | Designated for Assignment |
| Nate Karns | SP | 28.281 | Seattle Mariners | Seattle Mariners (MLB) | Transferred to 60-day DL |
| Evan Scribner | RP | 31.044 | Seattle Mariners | Seattle Mariners (MLB) | Activated from DL |
| Collin Cowgill | LF | 30.102 | Cleveland Indians | Columbus (AAA) | Designated for Assignment |
| Adam Moore | C | 32.116 | Cleveland Indians | Cleveland Indians (MLB) | Contract purchased from minors |
| Erik Gonzalez | 2B | 25.001 | Cleveland Indians | Cleveland Indians (MLB) | Recalled from Columbus (AAA) |
| Joseph Colon | RP | 26.195 | Cleveland Indians | Cleveland Indians (MLB) | Recalled from Columbus (AAA) |
| Cody Anderson | RP | 25.352 | Cleveland Indians | Cleveland Indians (MLB) | Recalled from Columbus (AAA) |
| Danny Salazar | SP | 26.233 | Cleveland Indians | Cleveland Indians (MLB) | Reinstated from paternity leave |
| Matt Reynolds | RP | 31.334 | San Francisco Giants | San Francisco Giants (MLB) | Recalled from Sacramento (AAA) |
| John Hicks | 1B | 27.001 | Detroit Tigers | Detroit Tigers (MLB) | Recalled from Toledo (AAA) |
| Buck Farmer | SP | 25.193 | Detroit Tigers | Detroit Tigers (MLB) | Recalled from Toledo (AAA) |
| Jeff Ferrell | RP | 25.282 | Detroit Tigers | Detroit Tigers (MLB) | Signed to Minor League Contract |
| Kevan Smith | C | 28.065 | Chicago White Sox | Chicago White Sox (MLB) | Recalled from Charlotte (AAA) |
| Juan Minaya | RP | 25.348 | Chicago White Sox | Chicago White Sox (MLB) | Recalled from Charlotte (AAA) |
| Eric O'Flaherty | RP | 31.208 | Atlanta Braves | Atlanta Braves (MLB) | Transferred to 60-day DL |
| Jed Bradley | RP | 26.081 | Atlanta Braves | Atlanta Braves (MLB) | Contract purchased from minors |
| Chris Withrow | RP | 27.153 | Atlanta Braves | Atlanta Braves (MLB) | Activated from DL |
| Ryan Buchter | RP | 29.200 | San Diego Padres | San Diego Padres (MLB) | Recalled from El Paso (AAA) |
| Josh Osich | RP | 27.363 | San Francisco Giants | San Francisco Giants (MLB) | Activated from DL |
| Mac Williamson | OF | 26.048 | San Francisco Giants | San Francisco Giants (MLB) | Activated from DL |
| Ty Blach | RP | 25.316 | San Francisco Giants | San Francisco Giants (MLB) | Recalled from Sacramento (AAA) |
| Steven Okert | RP | 25.054 | San Francisco Giants | San Francisco Giants (MLB) | Recalled from Sacramento (AAA) |
| Matt Reynolds | 3B | 25.272 | New York Mets | New York Mets (MLB) | Recalled from Las Vegas (AAA) |
| Kelby Tomlinson | SS | 26.077 | San Francisco Giants | San Francisco Giants (MLB) | Recalled from Sacramento (AAA) |
| Josh Thole | C | 29.308 | Toronto Blue Jays | Toronto Blue Jays (MLB) | Signed to 1-year contract for 2016-2016 ($0m) |
| Eddie Gamboa | RP | 31.254 | Tampa Bay Rays | Tampa Bay Rays (MLB) | Contract purchased from minors |
| Ryan Garton | RP | 26.270 | Tampa Bay Rays | Tampa Bay Rays (MLB) | Recalled from Durham (AAA) |
| Curt Casali | DH | 27.296 | Tampa Bay Rays | Tampa Bay Rays (MLB) | Recalled from Durham (AAA) |
| Louis Coleman | RP | 30.150 | Los Angeles Dodgers | Los Angeles Dodgers (MLB) | Recalled from Oklahoma City (AAA) |
| Austin Barnes | C | 26.247 | Los Angeles Dodgers | Los Angeles Dodgers (MLB) | Recalled from Oklahoma City (AAA) |
| Byron Buxton | CF | 22.257 | Minnesota Twins | Minnesota Twins (MLB) | Recalled from Rochester (AAA) |
| A.J. Morris | P | 29.274 | Cincinnati Reds | Louisville (AAA) | Activated from DL and outrighted to minors |
| Will Middlebrooks | SS | 27.357 | Milwaukee Brewers | Colorado Springs (AAA) | Activated from DL and outrighted to minors |
| Audry Perez | C | 27.252 | Baltimore Orioles | Norfolk (AAA) | DL-7 Injured |
| Brian Clark | P | 23.127 | Chicago White Sox | Birmingham (AA) | DL-7 Injured |
| Kyle Mcgowin | P | 24.279 | Los Angeles Angels | Salt Lake (AAA) | Placed on temporary inactive list |
| Brad Markey | P | 24.182 | Chicago Cubs | Tennessee (AA) | DL-7 Injured |
| Christopher McFarland | SS | 23.281 | Milwaukee Brewers | Biloxi (AA) | Placed on temporary inactive list |
| Cord Sandberg | CF | 21.242 | Philadelphia Phillies | Clearwater (A+) | DL-7 Injured |
| Drew Anderson | P | 22.163 | Philadelphia Phillies | Clearwater (A+) | DL-7 Injured |
| Shane Watson | P | 23.019 | Philadelphia Phillies | Clearwater (A+) | DL-7 Injured |
| Thomas Dorminy | P | 24.092 | San Diego Padres | Fort Wayne (A) | DL-7 Injured |
| Amalani Fukofuka | CF | 20.342 | Kansas City Royals | Lexington (A) | DL-7 Injured |
| Enmanuel Zabala | OF | 21.337 | New York Mets | Columbia (A) | DL-7 Injured |
| Yoiber Marquina | C | 20.211 | Cleveland Indians | Lake County (A) | DL-7 Injured |
| Steven Gallardo | P | 23.308 | | | Released by Cardinals |
