| Antonio Bastardo | RP | 30.315 | Pittsburgh Pirates | Pittsburgh Pirates (MLB) | Traded from Mets to Pirates for Jonathon Niese |
| Jesse Adams | p | 22.355 | Cincinnati Reds | Dayton (A) | Assigned to Dayton (A) |
| Scott Alexander | RP | 27.023 | Kansas City Royals | Omaha (AAA) | Assigned to Omaha (AAA) |
| Carlos Alonso | 2B | 28.169 | Philadelphia Phillies | Lehigh Valley (AAA) | Assigned to Lehigh Valley (AAA) |
| Beau Amaral | OF | 25.172 | Cincinnati Reds | Louisville (AAA) | Assigned to Louisville (AAA) |
| Chris Anderson | P | 24.004 | Los Angeles Dodgers | Rancho Cucamonga (A+) | Assigned to Rancho Cucamonga (A+) |
| Will Anderson | P | 23.341 | St. Louis Cardinals | Gulf Coast Cardinals (Rk) | Activated from disabled list |
| Francisco Arcia | C | 26.322 | Miami Marlins | New Orleans (AAA) | Assigned to New Orleans (AAA) |
| Carlos Arroyo | OF | 23.035 | Texas Rangers | Round Rock (AAA) | Assigned to Round Rock (AAA) |
| Chris Betts | c | 19.145 | Tampa Bay Rays | Hudson Valley (A-) | Assigned to Hudson Valley (A-) |
| Justin Bour | 1B | 28.066 | Miami Marlins | New Orleans (AAA) | Assigned to New Orleans (AAA) for rehab |
| Lewis Brinson | OF | 22.086 | Milwaukee Brewers | Colorado Springs (AAA) | Assigned to Colorado Springs (AAA) |
| Socrates Brito | CF | 23.330 | Arizona Diamondbacks | Reno (AAA) | Assigned to Reno (AAA) for rehab |
| Ryan Burr | p | 22.066 | Arizona Diamondbacks | Kane County (A) | Assigned to Kane County (A) |
| Trevor Cahill | RP | 28.154 | Chicago Cubs | Iowa (AAA) | Assigned to Iowa (AAA) for rehab |
| Anthony Caronia | IF-OF | 25.072 | Baltimore Orioles | Frederick (A+) | Assigned to Frederick (A+) |
| Jesus Castillo | P | 20.341 | Los Angeles Angels | Burlington (A) | Assigned to Burlington (A) |
| Lendy Castillo | RP | 27.116 | Cleveland Indians | Akron (AA) | Signed to Minor League Contract |
| Cito Culver | SS | 23.341 | New York Yankees | Scranton/Wilkes-Barre (AAA) | Assigned to Scranton/Wilkes-Barre (AAA) |
| Eduardo de Oleo | C | 23.189 | Arizona Diamondbacks | Kane County (A) | Assigned to Kane County (A) |
| Luis De Paula | P | 24.098 | Los Angeles Dodgers | Great Lakes (A) | Reinstated to active roster |
| Dominic DeMasi | P | 23.160 | Cleveland Indians | Lynchburg (A+) | Assigned to Lynchburg (A+) |
| Odrisamer Despaigne | RP | 29.120 | Baltimore Orioles | Norfolk (AAA) | Assigned to Norfolk (AAA) |
| Tanner English | OF | 23.144 | Minnesota Twins | Fort Myers (A+) | Assigned to Fort Myers (A+) |
| Brady Feigl | P | 25.218 | Atlanta Braves | Gulf Coast Braves (Rk) | Activated from disabled list |
| JP Feyereisen | P | 23.176 | New York Yankees | Trenton (AA) | Assigned to Trenton (AA) |
| Joshua Fields | RP | 30.348 | Los Angeles Dodgers | Oklahoma City (AAA) | Assigned to Oklahoma City (AAA) |
| Trevor Foss | P | 26.260 | Cleveland Indians | Lake County (A) | Signed to Minor League Contract |
| J.J. Franco | SS | 24.182 | Chicago White Sox | Kannapolis (A) | Assigned to Kannapolis (A) |
| Joey Gallo | LF | 22.256 | Texas Rangers | Round Rock (AAA) | Assigned to Round Rock (AAA) |
| Raywilly Gomez | C | 26.189 | New York Mets | Binghamton (AA) | Activated from disabled list |
| Trevor Gott | RP | 23.341 | Washington Nationals | Syracuse (AAA) | Assigned to Syracuse (AAA) |
| Randal Grichuk | CF | 24.355 | St. Louis Cardinals | Memphis (AAA) | Assigned to Memphis (AAA) |
| Yuli Gurriel | 2b | 32.054 | Houston Astros | Lancaster (A+) | Assigned to Lancaster (A+) |
| Brock Hartson | p | 22.358 | Cleveland Indians | Lynchburg (A+) | Assigned to Lynchburg (A+) |
| Joe Harvey | P | 24.206 | New York Yankees | Charleston (sc) (A) | Assigned to Charleston (sc) (A) |
| Taylor Hearn | p | 21.337 | Pittsburgh Pirates | West Virginia (A) | Assigned to West Virginia (A) |
| Dilson Herrera | 2B | 22.152 | Cincinnati Reds | Louisville (AAA) | Assigned to Louisville (AAA) |
| Cameron Hill | P | 22.070 | Cleveland Indians | Akron (AA) | Assigned to Akron (AA) |
| Grant Holmes | P | 20.133 | Oakland Athletics | Stockton (A+) | Assigned to Stockton (A+) |
| Brian Hunter | C | 23.253 | Cincinnati Reds | Dayton (A) | Activated from disabled list |
| Aaron Judge | OF | 24.098 | New York Yankees | Scranton/Wilkes-Barre (AAA) | Activated from disabled list |
| Jeremy Kehrt | P | 30.224 | Los Angeles Dodgers | Tulsa (AA) | Activated from disabled list |
| Joe Kelly | SP | 28.054 | Boston Red Sox | Pawtucket (AAA) | Assigned to Pawtucket (AAA) |
| Dean Kiekhefer | RP | 27.056 | St. Louis Cardinals | Memphis (AAA) | Assigned to Memphis (AAA) |
| Nick Kingham | P | 24.268 | Pittsburgh Pirates | Indianapolis (AAA) | Assigned to Indianapolis (AAA) |
| Keenan Kish | p | 24.255 | Cincinnati Reds | Dayton (A) | Assigned to Dayton (A) |
| Ricky Knapp | P | 24.074 | New York Mets | Binghamton (AA) | Assigned to Binghamton (AA) |
| Junior Lake | LF | 26.128 | Toronto Blue Jays | Buffalo (AAA) | Assigned to Buffalo (AAA) |
| Pat Light | P | 25.126 | Minnesota Twins | Rochester (AAA) | Assigned to Rochester (AAA) |
| Grayson Long | p | 22.067 | Los Angeles Angels | Burlington (A) | Assigned to Burlington (A) |
| Reynaldo Lopez | P | 22.210 | Washington Nationals | Syracuse (AAA) | Assigned to Syracuse (AAA) |
| Seth Lucio | P | 23.094 | San Diego Padres | Fort Wayne (A) | Activated from disabled list |
| Seth Lugo | P | 26.258 | New York Mets | Las Vegas (AAA) | Assigned to Las Vegas (AAA) |
| Evan Manarino | p | 23.217 | Oakland Athletics | Stockton (A+) | Assigned to Stockton (A+) |
| Jose Marmolejos | 1B | 23.212 | Washington Nationals | Harrisburg (AA) | Assigned to Harrisburg (AA) |
| Stanley Martinez | p | 21.246 | Detroit Tigers | Gulf Coast Tigers (East) (Rk) | Assigned to Gulf Coast Tigers (Rk) |
| Luis Mateo | P | 26.133 | New York Mets | Las Vegas (AAA) | Assigned to Las Vegas (AAA) |
| Erick Matta | c | 22.115 | Texas Rangers | Frisco (AA) | Reinstated to active roster |
| Austin Meadows | CF | 21.091 | Pittsburgh Pirates | Indianapolis (AAA) | Assigned to Indianapolis (AAA) |
| Heiker Meneses | SS-2B | 25.032 | Minnesota Twins | Rochester (AAA) | Assigned to Rochester (AAA) |
| Jio Mier | SS | 25.341 | Toronto Blue Jays | Buffalo (AAA) | Activated from disabled list |
| Jordan Montgomery | P | 23.218 | New York Yankees | Scranton/Wilkes-Barre (AAA) | Assigned to Scranton/Wilkes-Barre (AAA) |
| Jairo Munoz | P | 24.356 | Philadelphia Phillies | Clearwater (A+) | Assigned to Clearwater (A+) |
| Michael Murray | p | 22.310 | Oakland Athletics | Beloit (A) | Assigned to Beloit (A) |
| Brandon Nimmo | CF | 23.128 | New York Mets | Las Vegas (AAA) | Assigned to Las Vegas (AAA) |
| Sean O'Sullivan | SP | 28.336 | Boston Red Sox | Pawtucket (AAA) | Assigned to Pawtucket (AAA) for rehab |
| Walker Olis | of | 22.090 | Miami Marlins | Batavia (A-) | Assigned to Batavia (A-) |
| David Paulino | P | 22.177 | Houston Astros | Gulf Coast Astros (Rk) | Reinstated to active roster |
| Jhon Peluffo | p | 19.047 | Baltimore Orioles | Delmarva (A) | Assigned to Delmarva (A) |
| Jose Pena | P | 25.133 | New York Yankees | Charleston (sc) (A) | Assigned to Charleston (sc) (A) |
| Jose Peraza | SS | 22.094 | Cincinnati Reds | Louisville (AAA) | Assigned to Louisville (AAA) |
| Audry Perez | C | 27.222 | Baltimore Orioles | Norfolk (AAA) | Activated from disabled list |
| Tommy Peterson | p | 22.295 | Washington Nationals | Hagerstown (A) | Assigned to Hagerstown (A) |
| Wladimir Pinto | p | 18.171 | Detroit Tigers | Gulf Coast Tigers (East) (Rk) | Assigned to Gulf Coast Tigers (Rk) |
| Yasiel Puig | RF | 25.238 | Los Angeles Dodgers | Oklahoma City (AAA) | Assigned to Oklahoma City (AAA) |
| Juniel Querecuto | SS | 23.317 | Tampa Bay Rays | Durham (AAA) | Assigned to Durham (AAA) |
| Roman Quinn | SS | 23.080 | Philadelphia Phillies | Gulf Coast Phillies (Rk) | Assigned to Gulf Coast Phillies (Rk) |
| Zach Quintana | P | 22.109 | Atlanta Braves | Carolina (A+) | Activated from disabled list |
| Harold Ramirez | OF | 21.330 | Toronto Blue Jays | New Hampshire (AA) | Assigned to New Hampshire (AA) |
| Joely Rodriguez | P | 24.262 | Philadelphia Phillies | Lehigh Valley (AAA) | Assigned to Lehigh Valley (AAA) |
| Franderlyn Romero | P | 23.162 | Baltimore Orioles | Frederick (A+) | Assigned to Frederick (A+) |
| Jose Rosario | SS-2B | 24.247 | New York Yankees | Trenton (AA) | Assigned to Trenton (AA) |
| Sam Runion | P | 27.266 | Washington Nationals | Harrisburg (AA) | Assigned to Harrisburg (AA) |
| Edgar Santana | p | 24.291 | Pittsburgh Pirates | Indianapolis (AAA) | Assigned to Indianapolis (AAA) |
| Trae Santos | P | 23.295 | San Diego Padres | San Antonio (AA) | Assigned to San Antonio (AA) |
| Jacob Shortslef | p | 21.216 | Texas Rangers | Hickory (A) | Assigned to Hickory (A) |
| Jack Snodgrass | P | 28.236 | Texas Rangers | Frisco (AA) | Assigned to Frisco (AA) |
| Jorge Soler | LF | 24.159 | Chicago Cubs | Tennessee (AA) | Assigned to Tennessee (AA) for rehab |
| Craig Stammen | RP | 32.146 | Cleveland Indians | Columbus (AAA) | Assigned to Columbus (AAA) |
| Andrew Susac | C | 26.133 | Milwaukee Brewers | Colorado Springs (AAA) | Assigned to Colorado Springs (AAA) |
| Rodrigo Takahashi | P | 19.191 | Arizona Diamondbacks | Kane County (A) | Assigned to Kane County (A) |
| Lane Thomas | OF | 20.345 | Toronto Blue Jays | Lansing (A) | Assigned to Lansing (A) |
| Oliver Toribio | c | 20.056 | Houston Astros | Tri City (A-) | Assigned to Tri City (A-) |
| Spencer Turnbull | P | 23.318 | Detroit Tigers | West Michigan (A) | Assigned to West Michigan (A) |
| Luis Urias | SS | 19.060 | San Diego Padres | Lake Elsinore (A+) | Activated from disabled list |
| J.B. Wendelken | P | 23.131 | Oakland Athletics | Nashville (AAA) | Assigned to Nashville (AAA) |
| Tyler Wilson | SP | 26.311 | Baltimore Orioles | Norfolk (AAA) | Assigned to Norfolk (AAA) |
| Austin Wynns | C | 25.235 | Baltimore Orioles | Frederick (A+) | Assigned to Frederick (A+) |
| Ashur Tolliver | P | 28.191 | Baltimore Orioles | Norfolk (AAA) | DL-7 Injured |
| Jermaine Curtis | LF-3B | 29.023 | Cincinnati Reds | Louisville (AAA) | DL-7 Injured |
| Daniel Robertson | SS | 22.133 | Tampa Bay Rays | Durham (AAA) | DL-7 Injured |
| Patrick Kivlehan | 3B | 26.223 | Seattle Mariners | Tacoma (AAA) | Designated for Assignment |
| Tyler Jay | p | 22.105 | Minnesota Twins | Chattanooga (AA) | DL-7 Injured |
| Austin Aune | OF | 22.330 | New York Yankees | Tampa (A+) | |
| Matt Crownover | p | 23.150 | Washington Nationals | Potomac (A+) | Placed on temporary inactive list |
| Shawon Dunston | CF | 23.178 | San Francisco Giants | Augusta (A) | DL-7 Injured |
| Thomas Pannone | OF | 22.096 | Cleveland Indians | Lynchburg (A+) | DL-7 Injured |
| Alejandro Salazar | ss | 19.301 | Atlanta Braves | Rome (A) | DL-7 Injured |
| Edwin Diaz | SS | 20.343 | Oakland Athletics | Beloit (A) | DL-7 Injured |
| Greg Brody | IF | 24.285 | San Francisco Giants | Augusta (A) | DL-7 Injured |
| Juan Ortiz | OF | 21.316 | Milwaukee Brewers | Wisconsin (A) | DL-7 Injured |
| Juan Perez | P | 21.011 | St. Louis Cardinals | Peoria (A) | DL-7 Injured |
| Trent Grisham | of | 19.274 | Milwaukee Brewers | Wisconsin (A) | Placed on temporary inactive list |
| Wigberto Nevarez | C | 24.320 | Atlanta Braves | Rome (A) | DL-7 Injured |
| Remey Reed | p | 21.089 | Miami Marlins | Batavia (A-) | DL-7 Injured |
| Isaac Padilla | p | 20.049 | New York Yankees | Dominican Yankees (Rk) | Assigned to DSL Yankees 2 (Rk) |
| Orby Taveras | P | 21.320 | New York Yankees | Dominican Yankees (Rk) | Assigned to DSL Yankees (Rk) |
| Saul Martinez | p | 21.042 | Houston Astros | Gulf Coast Astros (Rk) | Assigned to GCL Astros (Rk) |
| Robby Sexton | p | 22.095 | Boston Red Sox | Gulf Coast Red Sox (Rk) | Signed out of draft (Wright State) |
| Carlos Corporan | C | 32.208 | | | Released by Marlins |
| Jhony Brito | p | 18.166 | New York Yankees | Gulf Coast Yankees (Rk) | Assigned to GCL Yankees East (Rk) |
| Rony Garcia | p | 18.226 | New York Yankees | Gulf Coast Yankees (Rk) | Assigned to GCL Yankees East (Rk) |
| Asdrubal Cabrera | SS | 30.262 | New York Mets | New York Mets (MLB) | DL-15 Strained patella tendon in left knee |
| Deven Marrero | 2B | 25.342 | Boston Red Sox | Pawtucket (AAA) | Activated from DL |
