| Joaquin Benoit | RP | 39.001 | Toronto Blue Jays | Toronto Blue Jays (MLB) | Traded from Mariners to Blue Jays for Drew Storen |
| Drew Storen | RP | 28.351 | Seattle Mariners | Seattle Mariners (MLB) | Traded from Blue Jays to Mariners for Joaquin Benoit |
| Joey Gallo | LF | 22.250 | Texas Rangers | Texas Rangers (MLB) | Recalled from Round Rock (AAA) |
| Julio Borbon | LF-CF | 30.157 | Baltimore Orioles | Baltimore Orioles (MLB) | Designated for Assignment |
| Hyun-Soo Kim | LF | 28.197 | Baltimore Orioles | Baltimore Orioles (MLB) | Activated from DL |
| Ubaldo Jimenez | SP | 32.187 | Baltimore Orioles | Baltimore Orioles (MLB) | Reinstated from paternity leave |
| Todd Cunningham | LF | 27.129 | Los Angeles Angels | Los Angeles Angels (MLB) | Designated for Assignment |
| Tyler Skaggs | SP | 25.014 | Los Angeles Angels | Los Angeles Angels (MLB) | Recalled from Salt Lake (AAA) |
| Clayton Richard | RP | 32.319 | Chicago Cubs | Chicago Cubs (MLB) | Designated for Assignment |
| J.B. Wendelken | P | 23.125 | Oakland Athletics | Oakland Athletics (MLB) | Recalled from Nashville (AAA) |
| Nick Martinez | RP | 25.356 | Texas Rangers | Texas Rangers (MLB) | Recalled from Round Rock (AAA) |
| Kyle Lohse | RP | 37.296 | Texas Rangers | Texas Rangers (MLB) | Designated for Assignment |
| Eric Fryer | C | 30.335 | Pittsburgh Pirates | Pittsburgh Pirates (MLB) | Reinstated from paternity leave |
| Ryan Zimmerman | 1B | 31.302 | Washington Nationals | Washington Nationals (MLB) | Activated from DL |
| Adalberto Mondesi | 2B | 21.000 | Kansas City Royals | Kansas City Royals (MLB) | Recalled from Omaha (AAA) |
| Sammy Solis | RP | 27.351 | Washington Nationals | Washington Nationals (MLB) | Activated from DL |
| Josh Smoker | P | 27.243 | New York Mets | New York Mets (MLB) | Recalled from Las Vegas (AAA) |
| Sam Tuivailala | RP | 23.281 | St. Louis Cardinals | St. Louis Cardinals (MLB) | Recalled from Memphis (AAA) |
| Dean Kiekhefer | RP | 27.050 | St. Louis Cardinals | St. Louis Cardinals (MLB) | Recalled from Memphis (AAA) |
| Trevor Rosenthal | CL | 26.059 | St. Louis Cardinals | St. Louis Cardinals (MLB) | DL-15 Right rotator cuff inflammation |
| B.J. Upton | LF-CF | 31.340 | Toronto Blue Jays | Toronto Blue Jays (MLB) | Traded from Padres to Blue Jays for Hansel Rodriguez |
| Hansel Rodriguez | P | 19.150 | San Diego Padres | San Diego Padres (MLB) | Traded from Blue Jays to Padres for Melvin Upton Jr. |
| Keyder Aristigueta | 2b | 20.176 | Atlanta Braves | Gulf Coast Braves (Rk) | Assigned to Gulf Coast Braves (Rk) |
| Moises Bello | 3b | 19.044 | Atlanta Braves | Gulf Coast Braves (Rk) | Assigned to Gulf Coast Braves (Rk) |
| Javier Betancourt | SS-3B | 21.080 | Milwaukee Brewers | Biloxi (AA) | Activated from disabled list |
| Clayton Blackburn | P | 23.202 | San Francisco Giants | Sacramento (AAA) | Activated from disabled list |
| Felipe Blanco | SS | 22.230 | San Diego Padres | El Paso (AAA) | Assigned to El Paso (AAA) |
| Lisandro Blanco | of | 19.195 | New York Yankees | Gulf Coast Yankees (Rk) | Assigned to Gulf Coast Yankees (Rk) |
| Anthony Caronia | IF-OF | 25.066 | Baltimore Orioles | Bowie (AA) | Assigned to Bowie (AA) |
| Jared Cheek | p | 23.269 | Chicago Cubs | South Bend (A) | Assigned to South Bend (A) |
| Nick Ciuffo | C | 21.142 | Tampa Bay Rays | Gulf Coast Rays (Rk) | Activated from disabled list |
| Jimmy Cordero | P | 24.282 | Philadelphia Phillies | Reading (AA) | Assigned to Reading (AA) |
| Cortland Cox | P | 21.266 | Cleveland Indians | Lake County (A) | Assigned to Lake County (A) |
| Isrrael De la Cruz | ss | 19.042 | Atlanta Braves | Gulf Coast Braves (Rk) | Assigned to Gulf Coast Braves (Rk) |
| Juan De La Cruz | C | 22.356 | Cleveland Indians | Lake County (A) | Assigned to Lake County (A) |
| Oscar De La Cruz | p | 21.145 | Chicago Cubs | South Bend (A) | Assigned to South Bend (A) |
| Bairon De La Rosa | p | 20.010 | Atlanta Braves | Gulf Coast Braves (Rk) | Assigned to Gulf Coast Braves (Rk) |
| Austin DeCarr | P | 21.135 | New York Yankees | Charleston (sc) (A) | Assigned to Charleston (sc) (A) |
| Nicky Delmonico | 1B-2B | 24.015 | Chicago White Sox | Charlotte (AAA) | Activated from disabled list |
| Donnie Dewees | of | 22.301 | Chicago Cubs | Myrtle Beach (A+) | Assigned to Myrtle Beach (A+) |
| Denis Diaz | p | 21.249 | Toronto Blue Jays | Vancouver (A-) | Assigned to Vancouver (A-) |
| Matt Esparza | p | 21.339 | Cleveland Indians | Lynchburg (A+) | Assigned to Lynchburg (A+) |
| Bryant Flete | 2B | 23.177 | Chicago Cubs | Myrtle Beach (A+) | Assigned to Myrtle Beach (A+) |
| Dante Flores | 2b | 23.110 | Chicago White Sox | Arizona White Sox (Rk) | Activated from disabled list |
| Junior Flores | p | 21.287 | Milwaukee Brewers | Wisconsin (A) | Assigned to Wisconsin (A) |
| J.J. Franco | SS | 24.176 | Chicago White Sox | Arizona White Sox (Rk) | Activated from disabled list |
| Jose Fuentes | p | 21.294 | Atlanta Braves | Gulf Coast Braves (Rk) | Assigned to Gulf Coast Braves (Rk) |
| Alexis Garcia | ss | 19.026 | Atlanta Braves | Gulf Coast Braves (Rk) | Assigned to Gulf Coast Braves (Rk) |
| Brian Gilbert | P | 23.352 | Minnesota Twins | Fort Myers (A+) | Activated from disabled list |
| Gerardo Gonzalez | ss | 17.218 | Atlanta Braves | Gulf Coast Braves (Rk) | Assigned to Gulf Coast Braves (Rk) |
| Jose Gonzalez | of | 18.013 | Atlanta Braves | Gulf Coast Braves (Rk) | Assigned to Gulf Coast Braves (Rk) |
| Jesus Graterol | ss | 19.107 | New York Yankees | Gulf Coast Yankees (Rk) | Assigned to Gulf Coast Yankees (Rk) |
| Carlos Guzman | if | 18.072 | Atlanta Braves | Gulf Coast Braves (Rk) | Assigned to Gulf Coast Braves (Rk) |
| Jordan Harrison | P | 25.109 | Tampa Bay Rays | Montgomery (AA) | Assigned to Montgomery (AA) |
| Jeremy Hefner | SP | 30.138 | St. Louis Cardinals | Memphis (AAA) | Activated from disabled list |
| Marc Huberman | p | 22.198 | Chicago Cubs | Eugene (A-) | Assigned to Eugene (A-) |
| Xavier Javier | p | 18.168 | Atlanta Braves | Gulf Coast Braves (Rk) | Assigned to Gulf Coast Braves (Rk) |
| Trevor Lane | p | 22.092 | New York Yankees | Gulf Coast Yankees (Rk) | Assigned to Gulf Coast Yankees (Rk) |
| Chase Livingston | c | 22.112 | Kansas City Royals | Burlington (Rk) | Assigned to Burlington (Rk) |
| Shed Long | C | 20.340 | Cincinnati Reds | Daytona (A+) | Assigned to Daytona (A+) |
| Ronaldo Lopez | p | 18.201 | Atlanta Braves | Gulf Coast Braves (Rk) | Assigned to Gulf Coast Braves (Rk) |
| Edel Luaces | of | 22.074 | New York Yankees | Gulf Coast Yankees (Rk) | Assigned to Gulf Coast Yankees (Rk) |
| Josh Lucas | P | 25.264 | St. Louis Cardinals | Springfield (AA) | Assigned to Springfield (AA) |
| Nathan Lukes | of | 22.015 | Cleveland Indians | Lynchburg (A+) | Assigned to Lynchburg (A+) |
| Carlos Machado | of | 18.052 | Houston Astros | Greeneville (Rk) | Assigned to Greeneville (Rk) |
| Vimael Machin | ss | 22.305 | Chicago Cubs | South Bend (A) | Assigned to South Bend (A) |
| Westhers Magdaleno | ss | 19.270 | San Diego Padres | Lake Elsinore (A+) | Assigned to Lake Elsinore (A+) |
| Connor Marabell | of | 22.121 | Cleveland Indians | Lynchburg (A+) | Assigned to Lynchburg (A+) |
| JD Martin | P | 33.206 | Washington Nationals | Gulf Coast Nationals (Rk) | Assigned to Gulf Coast Nationals (Rk) |
| Stanley Martinez | p | 21.240 | Atlanta Braves | Gulf Coast Braves (Rk) | Assigned to Gulf Coast Braves (Rk) |
| Algeni Mateo | C | 20.361 | New York Yankees | Gulf Coast Yankees (Rk) | Assigned to Gulf Coast Yankees (Rk) |
| Jhonny Mateo | p | 21.342 | Atlanta Braves | Gulf Coast Braves (Rk) | Assigned to Gulf Coast Braves (Rk) |
| Reydel Medina | OF | 23.163 | Cincinnati Reds | Daytona (A+) | Assigned to Daytona (A+) |
| Bringnel Mendez | p | 22.177 | New York Yankees | Gulf Coast Yankees (Rk) | Assigned to Gulf Coast Yankees (Rk) |
| Erick Mendez | of | 20.111 | New York Yankees | Gulf Coast Yankees (Rk) | Assigned to Gulf Coast Yankees (Rk) |
| Micah Miniard | P | 20.106 | Cleveland Indians | Lake County (A) | Assigned to Lake County (A) |
| Melvin Morel | p | 22.225 | Atlanta Braves | Gulf Coast Braves (Rk) | Assigned to Gulf Coast Braves (Rk) |
| Connor Myers | of | 22.174 | Chicago Cubs | South Bend (A) | Assigned to South Bend (A) |
| Brian Navarreto | C | 21.210 | Minnesota Twins | Fort Myers (A+) | Activated from disabled list |
| James Norwood | P | 22.215 | Chicago Cubs | Myrtle Beach (A+) | Assigned to Myrtle Beach (A+) |
| Garrett Nuss | P | 23.103 | Los Angeles Angels | Inland Empire (A+) | Assigned to Inland Empire (A+) |
| Braulio Ortiz | P | 24.220 | Cincinnati Reds | Dayton (A) | Assigned to Dayton (A) |
| Tyler Peitzmeier | p | 23.151 | Chicago Cubs | Eugene (A-) | Assigned to Eugene (A-) |
| Wladimir Pinto | p | 18.165 | Atlanta Braves | Gulf Coast Braves (Rk) | Assigned to Gulf Coast Braves (Rk) |
| Emmanuel Ramirez | p | 22.012 | San Diego Padres | Fort Wayne (A) | Assigned to Fort Wayne (A) |
| Matt Ramsey | P | 26.306 | Miami Marlins | Jacksonville (AA) | Assigned to Jacksonville (AA) |
| Zac Reininger | P | 23.180 | Detroit Tigers | Lakeland (A+) | Assigned to Lakeland (A+) |
| J.T. Riddle | SS | 24.289 | Miami Marlins | Jacksonville (AA) | Activated from disabled list |
| Jared Robinson | P | 21.249 | Cleveland Indians | Lynchburg (A+) | Assigned to Lynchburg (A+) |
| Alexander Rodriguez | of | 18.136 | Atlanta Braves | Gulf Coast Braves (Rk) | Assigned to Gulf Coast Braves (Rk) |
| Hansel Rodriguez | P | 19.150 | San Diego Padres | Tri-City (A-) | Assigned to Tri-City (A-) |
| Hector Rodriguez | p | 19.235 | Atlanta Braves | Gulf Coast Braves (Rk) | Assigned to Gulf Coast Braves (Rk) |
| Jesus Rodriguez | p | 18.161 | Atlanta Braves | Gulf Coast Braves (Rk) | Assigned to Gulf Coast Braves (Rk) |
| Yonauris Rodriguez | ss | 19.139 | New York Yankees | Gulf Coast Yankees (Rk) | Assigned to Gulf Coast Yankees (Rk) |
| Chris Sadberry | P | 24.262 | Miami Marlins | Gulf Coast Marlins (Rk) | Activated from disabled list |
| Javi Salas | P | 24.129 | Milwaukee Brewers | Arizona Brewers (Rk) | Assigned to Arizona Brewers (Rk) |
| Jose Salas | ss | 19.101 | Atlanta Braves | Gulf Coast Braves (Rk) | Assigned to Gulf Coast Braves (Rk) |
| Adrian Sanchez | 2B | 25.345 | Washington Nationals | Harrisburg (AA) | Assigned to Harrisburg (AA) |
| Kilber Santana | p | 17.285 | Atlanta Braves | Gulf Coast Braves (Rk) | Assigned to Gulf Coast Braves (Rk) |
| Tony Santillan | p | 19.103 | Cincinnati Reds | Dayton (A) | Assigned to Dayton (A) |
| Bo Schultz | RP | 30.305 | Toronto Blue Jays | Buffalo (AAA) | Assigned to Buffalo (AAA) |
| Jordan Scott | of | 19.065 | New York Yankees | Gulf Coast Yankees (Rk) | Assigned to Gulf Coast Yankees (Rk) |
| Jordan Sheffield | p | 21.056 | Los Angeles Dodgers | Arizona Dodgers (Rk) | Assigned to Arizona Dodgers (Rk) |
| Josh Smoker | P | 27.243 | New York Mets | Las Vegas (AAA) | Assigned to Las Vegas (AAA) |
| Austin Sweet | p | 22.309 | Tampa Bay Rays | Princeton (Rk) | Assigned to Princeton (Rk) |
| Daniel Sweet | of | 21.211 | Cincinnati Reds | Dayton (A) | Assigned to Dayton (A) |
| Rodrigo Takahashi | P | 19.185 | Arizona Diamondbacks | Hillsboro (A-) | Assigned to Hillsboro (A-) |
| Cristhian Tortosa | p | 17.270 | Atlanta Braves | Gulf Coast Braves (Rk) | Assigned to Gulf Coast Braves (Rk) |
| Sam Tuivailala | RP | 23.281 | St. Louis Cardinals | Memphis (AAA) | Assigned to Memphis (AAA) |
| Ryan Uhl | 1b | 23.062 | Seattle Mariners | Clinton (A) | Assigned to Clinton (A) |
| Framber Valdez | p | 22.250 | Houston Astros | Quad Cities (A) | Assigned to Quad Cities (A) |
| Ryan Vega | of | 19.313 | Los Angeles Angels | Orem (Rk) | Assigned to Orem (Rk) |
| Carlos Vidal | of | 20.241 | New York Yankees | Tampa (A+) | Assigned to Tampa (A+) |
| Javier Villarroel | p | 18.269 | Atlanta Braves | Gulf Coast Braves (Rk) | Assigned to Gulf Coast Braves (Rk) |
| Jose Vinicio | SS | 23.017 | Boston Red Sox | Pawtucket (AAA) | Activated from disabled list |
| Ryan Vogelsong | RP | 39.005 | Pittsburgh Pirates | Indianapolis (AAA) | Assigned to Indianapolis (AAA) for rehab |
| Brandon Wagner | 3b | 20.338 | New York Yankees | Gulf Coast Yankees (Rk) | Assigned to Gulf Coast Yankees (Rk) |
| John Walter | P | 25.068 | St. Louis Cardinals | Palm Beach (A+) | Assigned to Palm Beach (A+) |
| Alex Webb | p | 22.008 | Cincinnati Reds | Dayton (A) | Assigned to Dayton (A) |
| NIck Wells | P | 20.157 | Seattle Mariners | Clinton (A) | Assigned to Clinton (A) |
| Jacob Wilson | IF | 25.363 | St. Louis Cardinals | Springfield (AA) | Assigned to Springfield (AA) |
| Stephen Wrenn | of | 21.293 | Houston Astros | Quad Cities (A) | Assigned to Quad Cities (A) |
| Collin Yelich | c | 22.299 | Atlanta Braves | Gulf Coast Braves (Rk) | Assigned to Gulf Coast Braves (Rk) |
| Josh Zeid | RP | 29.125 | New York Mets | Las Vegas (AAA) | Assigned to Las Vegas (AAA) |
| Shane Zeile | C | 23.043 | Detroit Tigers | West Michigan (A) | Activated from disabled list |
| Audry Perez | C | 27.216 | Baltimore Orioles | Norfolk (AAA) | DL-7 Injured |
| Daniel Fields | CF | 25.185 | Los Angeles Dodgers | Tulsa (AA) | DL-7 Injured |
| Michael Choice | RF | 26.259 | Cleveland Indians | Columbus (AAA) | Placed on temporary inactive list |
| Bryson Smith | CF | 27.222 | Cincinnati Reds | Louisville (AAA) | DL-7 Injured |
| Jack Mayfield | IF-P | 25.300 | Houston Astros | Fresno (AAA) | DL-7 Injured |
| Jeremy Kehrt | P | 30.218 | Los Angeles Dodgers | Tulsa (AA) | DL-7 Injured |
| Luis Urias | SS | 19.054 | San Diego Padres | Lake Elsinore (A+) | DL-7 Injured |
| Tyler Ogle | C | 25.352 | Los Angeles Dodgers | Tulsa (AA) | DL-7 Injured |
| Webster Rivas | C | 25.353 | Los Angeles Angels | Inland Empire (A+) | Placed on temporary inactive list |
| Bruce Caldwell | SS | 24.243 | St. Louis Cardinals | Springfield (AA) | DL-7 Injured |
| Danry Vasquez | RF | 22.200 | Houston Astros | Corpus Christi (AA) | Suspended for charging the mound |
| David Berg | p | 23.121 | Chicago Cubs | Tennessee (AA) | DL-7 Injured |
| Jake Skole | CF | 24.192 | | | Released by Yankees |
| Michael O'Neal | p | 24.052 | Atlanta Braves | Carolina (A+) | DL-7 Injured |
| Niko Goodrum | SS | 24.150 | Minnesota Twins | Chattanooga (AA) | DL-7 Injured |
| Shawn Pleffner | RF | 26.344 | Washington Nationals | Harrisburg (AA) | DL-7 Injured |
| Tyler Pike | P | 22.182 | Seattle Mariners | Bakersfield (A+) | DL-7 Injured |
| Andrew Brodbeck | 2b | 23.186 | St. Louis Cardinals | Palm Beach (A+) | DL-7 Injured |
| Dariel Delgado | P | 22.335 | Baltimore Orioles | Delmarva (A) | DL-7 Injured |
| Darren Seferina | 2B | 22.184 | St. Louis Cardinals | Palm Beach (A+) | DL-7 Injured |
| Jacob Evans | p | 21.242 | St. Louis Cardinals | Palm Beach (A+) | DL-7 Injured |
| Victor Robles | of | 19.069 | Washington Nationals | Potomac (A+) | DL-7 Injured |
| Yorman Landa | P | 22.046 | Minnesota Twins | Fort Myers (A+) | DL-7 Injured |
| Cristhopher Santamaria | P | 20.038 | | | Released by Astros |
| Ke'Bryan Hayes | 3b | 19.180 | Pittsburgh Pirates | West Virginia (A) | DL-7 Injured |
| Brett Adcock | p | 20.334 | Houston Astros | Tri City (A-) | DL-60 Injured |
| Tucker Ward | p | 24.078 | Arizona Diamondbacks | Hillsboro (A-) | DL-60 Injured |
| Andrew Wright | p | 21.030 | Cincinnati Reds | Arizona Reds (Rk) | DL-60 Injured |
| Brandon Benavente | c | 18.327 | Houston Astros | Dominican Astros Blue (Rk) | Assigned to DSL Astros Blue (Rk) |
| Rafael Santana | of | 20.277 | Arizona Diamondbacks | Dominican Diamondbacks (Rk) | Assigned to DSL Diamondbacks (Rk) |
| Chavez Young | of | 18.353 | Toronto Blue Jays | Gulf Coast Blue Jays (Rk) | Signed out of draft (Georgia HS) |
| Dom Abbadessa | of | 18.231 | Toronto Blue Jays | Gulf Coast Blue Jays (Rk) | Signed out of draft (California HS) |
| Craig Breslow | RP | 35.353 | Texas Rangers | Round Rock (AAA) | Signed to Minor League Contract |
| Deven Marrero | 2B | 25.336 | Boston Red Sox | Pawtucket (AAA) | DL-7 Injured |
