| Eric Surkamp | RP | 28.358 | | | Released and Signed with Hanwha (Korea) |
| Will Venable | CF-RF | 33.252 | Los Angeles Dodgers | Los Angeles Dodgers (MLB) | Designated for Assignment |
| Carlos Frias | RP | 26.237 | Los Angeles Dodgers | Los Angeles Dodgers (MLB) | Recalled from Oklahoma City (AAA) |
| Hyun-Jin Ryu | SP | 29.105 | Los Angeles Dodgers | Los Angeles Dodgers (MLB) | Activated from DL |
| Ryan Lamarre | CF | 27.229 | Boston Red Sox | Boston Red Sox (MLB) | Designated for Assignment |
| Aaron Hill | 3B | 34.109 | Boston Red Sox | Boston Red Sox (MLB) | Traded from Brewers to Red Sox for Aaron Wilkerson and Wendell Rijo |
| Wendell Rijo | 2b | 20.308 | Milwaukee Brewers | Milwaukee Brewers (MLB) | Traded from Red Sox with Aaron Wilkerson to Brewers for Aaron Hill |
| Aaron Wilkerson | P | 27.044 | Milwaukee Brewers | Milwaukee Brewers (MLB) | Traded from Red Sox with Wendell Rijo to Brewers for Aaron Hill |
| Emilio Bonifacio | LF | 31.076 | Atlanta Braves | Atlanta Braves (MLB) | Designated for Assignment |
| Gordon Beckham | 2B | 29.295 | Atlanta Braves | Atlanta Braves (MLB) | Activated from DL |
| Zach McAllister | RP | 28.213 | Cleveland Indians | Cleveland Indians (MLB) | DL-15 Right hip discomfort |
| Joseph Colon | RP | 26.140 | Cleveland Indians | Cleveland Indians (MLB) | Contract purchased from minors |
| Austin Adams | RP | 29.323 | Cleveland Indians | Cleveland Indians (MLB) | Recalled from Columbus (AAA) |
| Justin Maxwell | RF | 32.245 | | | Signed with Lotte (Korea) |
| Pedro Alvarez | DH | 29.152 | Baltimore Orioles | Baltimore Orioles (MLB) | Reinstated from bereavement list |
| Tyler Glasnow | P | 22.319 | Pittsburgh Pirates | Pittsburgh Pirates (MLB) | Recalled from Indianapolis (AAA) |
| Matt Carpenter | 2B | 30.224 | St. Louis Cardinals | St. Louis Cardinals (MLB) | DL-15 Strained right oblique |
| Michael McKenry | C | 31.126 | St. Louis Cardinals | St. Louis Cardinals (MLB) | Contract purchased from minors |
| Jacob Stallings | C | 26.198 | Pittsburgh Pirates | Indianapolis (AAA) | Outrighted to minors |
| Angel Rodriguez | p | 18.161 | Tampa Bay Rays | Dominican Rays (Rk) | Assigned to DSL Rays (Rk) |
| Mayobanex Acosta | C | 28.231 | Tampa Bay Rays | Hudson Valley (A-) | Assigned to Hudson Valley (A-) |
| Aaron Altherr | CF | 25.175 | Philadelphia Phillies | Gulf Coast Phillies (Rk) | Assigned to GCL Phillies (Rk) |
| Dariel Alvarez | RF | 27.243 | Baltimore Orioles | Norfolk (AAA) | Assigned to Norfolk (AAA) |
| Beau Amaral | OF | 25.147 | Cincinnati Reds | Pensacola (AA) | Assigned to Pensacola (AA) |
| Drew Anderson | P | 22.108 | Philadelphia Phillies | Clearwater (A+) | Assigned to Clearwater (A+) |
| Bronson Arroyo | SP | 39.134 | Washington Nationals | Syracuse (AAA) | Activated from disabled list |
| Jesus Atencio | c | 19.320 | Kansas City Royals | Lexington (A) | Assigned to Lexington (A) |
| Luis Avilan | RP | 26.354 | Los Angeles Dodgers | Oklahoma City (AAA) | Assigned to Oklahoma City (AAA) |
| Agapito Barrios | p | 22.220 | Houston Astros | Gulf Coast Astros (Rk) | Activated from disabled list |
| Palmer Betts | P | 22.086 | Arizona Diamondbacks | Visalia (A+) | Assigned to Visalia (A+) |
| Patrick Biondi | OF | 25.180 | New York Mets | St. Lucie (A+) | Activated from disabled list |
| Ismael Cabrera | p | 22.019 | Philadelphia Phillies | Gulf Coast Phillies (Rk) | Assigned to Gulf Coast Phillies (Rk) |
| Andrew Case | P | 23.183 | Toronto Blue Jays | Lansing (A) | Assigned to Lansing (A) |
| Ledarious Clark | of | 22.193 | Texas Rangers | Hickory (A) | Activated from disabled list |
| Corey Copping | p | 22.178 | Los Angeles Dodgers | Rancho Cucamonga (A+) | Assigned to Rancho Cucamonga (A+) |
| Chris Cotton | P | 25.229 | Houston Astros | Corpus Christi (AA) | Activated from disabled list |
| Austin Davidson | IF | 23.186 | Washington Nationals | Potomac (A+) | Assigned to Potomac (A+) |
| Austin Davis | P | 23.155 | Philadelphia Phillies | Lakewood (A) | Assigned to Lakewood (A) |
| Brendon Davis | 3b | 18.345 | Los Angeles Dodgers | Great Lakes (A) | Activated from disabled list |
| Taylor Davis | C | 26.222 | Chicago Cubs | Iowa (AAA) | Assigned to Iowa (AAA) |
| Ross Detwiler | RP | 30.124 | Cleveland Indians | Columbus (AAA) | Reinstated to active roster |
| Seranthony Dominguez | P | 21.225 | Philadelphia Phillies | Williamsport (A-) | Assigned to Williamsport (A-) |
| Drew Dosch | IF | 24.014 | Baltimore Orioles | Bowie (AA) | Activated from disabled list |
| Max Duval | p | 25.084 | Arizona Diamondbacks | Hillsboro (A-) | Assigned to Hillsboro (A-) |
| Matt Eureste | ss | 22.344 | Tampa Bay Rays | Charlotte (A+) | Assigned to Charlotte (A+) |
| Dana Eveland | RP | 32.253 | Tampa Bay Rays | Durham (AAA) | Outrighted to minors |
| Skyler Ewing | IF-C | 23.320 | San Francisco Giants | Augusta (A) | Activated from disabled list |
| Billy Fleming | 2B | 23.291 | New York Yankees | Trenton (AA) | Activated from disabled list |
| Wilmer Font | RP | 26.045 | Toronto Blue Jays | Buffalo (AAA) | Signed to Minor League Contract |
| Charlie Furbush | RP | 30.088 | Seattle Mariners | Everett (A-) | Assigned to Everett (A-) for rehab |
| Cameron Gann | p | 23.273 | Arizona Diamondbacks | Visalia (A+) | Assigned to Visalia (A+) |
| Edgar Garcia | P | 28.292 | Arizona Diamondbacks | Mobile (AA) | Assigned to Mobile (AA) |
| Edwin Garcia | SS-2B | 25.129 | Texas Rangers | Round Rock (AAA) | Assigned to Round Rock (AAA) |
| Lucas Giolito | P | 21.359 | Washington Nationals | Syracuse (AAA) | Assigned to Syracuse (AAA) |
| Tyler Glasnow | P | 22.319 | Pittsburgh Pirates | Indianapolis (AAA) | Assigned to Indianapolis (AAA) |
| Austin Gomber | P | 22.227 | St. Louis Cardinals | Springfield (AA) | Assigned to Springfield (AA) |
| Chi Chi Gonzalez | RP | 24.175 | Texas Rangers | Round Rock (AAA) | Assigned to Round Rock (AAA) |
| Matt Grace | RP | 27.206 | Washington Nationals | Syracuse (AAA) | Assigned to Syracuse (AAA) |
| Reed Gragnani | SS | 25.306 | Boston Red Sox | Salem (A+) | Assigned to Salem (A+) |
| Alec Grosser | P | 21.177 | Los Angeles Dodgers | Arizona Dodgers (Rk) | Assigned to Arizona Dodgers (Rk) |
| Hunter Harvey | P | 21.211 | Baltimore Orioles | Frederick (A+) | Assigned to Frederick (A+) |
| Drew Hutchison | RP | 25.320 | Toronto Blue Jays | Buffalo (AAA) | Assigned to Buffalo (AAA) |
| Danny Jansen | C | 21.084 | Toronto Blue Jays | Dunedin (A+) | Assigned to Dunedin (A+) |
| Spencer Johnson | of | 22.249 | Houston Astros | Tri City (A-) | Assigned to Tri City (A-) |
| Ben Klimesh | P | 26.055 | Cincinnati Reds | Pensacola (AA) | Activated from disabled list |
| John Lannan | SP | 31.284 | Kansas City Royals | Northwest Arkansas (AA) | Assigned to Northwest Arkansas (AA) |
| Rainy Lara | P | 25.116 | New York Mets | Binghamton (AA) | Activated from disabled list |
| Matt Lollis | P | 25.300 | Chicago White Sox | Birmingham (AA) | Assigned to Birmingham (AA) |
| Brandon Macias | SS-3B | 27.271 | Milwaukee Brewers | Colorado Springs (AAA) | Assigned to Colorado Springs (AAA) |
| Austin Maddox | C | 25.056 | Boston Red Sox | Pawtucket (AAA) | Assigned to Pawtucket (AAA) |
| Angel Manzanarez | ss | 19.050 | New York Mets | Gulf Coast Mets (Rk) | Assigned to Gulf Coast Mets (Rk) |
| Matt Marsh | P | 24.364 | New York Yankees | Gulf Coast Yankees (Rk) | Assigned to Gulf Coast Yankees (Rk) |
| David Martinez | P | 28.339 | Detroit Tigers | Erie (AA) | Assigned to Erie (AA) |
| Juancito Martinez | RF | 27.028 | Miami Marlins | Batavia (A-) | Assigned to Batavia (A-) |
| Ryan McCormick | p | 22.115 | Colorado Rockies | Asheville (A) | Assigned to Asheville (A) |
| Narciso Mesa | CF | 24.235 | Washington Nationals | Hagerstown (A) | Assigned to Hagerstown (A) |
| Adam Miller | P | 26.192 | Arizona Diamondbacks | Mobile (AA) | Activated from disabled list |
| Adalberto Mondesi | OF | 20.347 | Kansas City Royals | Omaha (AAA) | Assigned to Omaha (AAA) |
| Adam Morgan | SP | 26.131 | Philadelphia Phillies | Lehigh Valley (AAA) | Assigned to Lehigh Valley (AAA) |
| Toru Murata | SP | 31.049 | Cleveland Indians | Columbus (AAA) | Assigned to Columbus (AAA) |
| Max Murphy | OF | 23.233 | Minnesota Twins | Fort Myers (A+) | Activated from disabled list |
| Efren Navarro | 1B | 30.055 | St. Louis Cardinals | Memphis (AAA) | Signed to Minor League Contract |
| Justin Nicolino | SP | 24.229 | Miami Marlins | New Orleans (AAA) | Assigned to New Orleans (AAA) |
| Trey Nielsen | P | 24.311 | St. Louis Cardinals | Memphis (AAA) | Assigned to Memphis (AAA) |
| Khayyan Norfork | 2B | 27.170 | Washington Nationals | Harrisburg (AA) | Assigned to Harrisburg (AA) |
| Zach Nuding | P | 26.101 | Los Angeles Angels | Arkansas (AA) | Assigned to Arkansas (AA) |
| Shane Opitz | SS | 24.180 | Toronto Blue Jays | Buffalo (AAA) | Assigned to Buffalo (AAA) |
| Randy Ortiz | OF | 23.023 | San Francisco Giants | San Jose (A+) | Activated from disabled list |
| Chris Paul | of | 23.269 | Minnesota Twins | Fort Myers (A+) | Activated from disabled list |
| Luis Paula | P | 23.016 | Pittsburgh Pirates | West Virginia (A-) | Assigned to West Virginia (A-) |
| Robert Pehl | OF | 23.288 | Kansas City Royals | Omaha (AAA) | Assigned to Omaha (AAA) |
| Zac Person | p | 23.268 | Houston Astros | Quad Cities (A) | Activated from disabled list |
| Dalton Pompey | CF | 23.209 | Toronto Blue Jays | Buffalo (AAA) | Activated from disabled list |
| Michael Pritchard | OF | 24.241 | St. Louis Cardinals | Palm Beach (A+) | Activated from disabled list |
| Benino Pruneda | P | 27.334 | Kansas City Royals | Wilmington (A+) | Assigned to Wilmington (A+) |
| Cristian Quintin | P | 22.193 | Colorado Rockies | Asheville (A) | Activated from disabled list |
| John Richy | P | 23.345 | Philadelphia Phillies | Reading (AA) | Assigned to Reading (AA) |
| Nick Roscetti | ss | 22.244 | Milwaukee Brewers | Brevard County (A+) | Assigned to Brevard County (A+) |
| Pat Ruotolo | p | 21.174 | San Francisco Giants | Salem-Keizer (A-) | Assigned to Salem-Keizer (A-) |
| Jared Ruxer | P | 23.344 | Los Angeles Angels | Inland Empire (A+) | Reinstated to active roster |
| Guilermo Salas | SS | 22.078 | Baltimore Orioles | Frederick (A+) | Assigned to Frederick (A+) |
| Adrian Sanchez | 2B | 25.326 | Washington Nationals | Syracuse (AAA) | Assigned to Syracuse (AAA) |
| Manny Sanchez | OF | 20.276 | Tampa Bay Rays | Bowling Green (A) | Activated from disabled list |
| Sam Selman | P | 25.236 | Kansas City Royals | Northwest Arkansas (AA) | Assigned to Northwest Arkansas (AA) |
| Jake Smith | P | 26.036 | San Diego Padres | San Antonio (AA) | Claimed off waivers from Giants by Padres |
| Glenn Sparkman | P | 24.058 | Kansas City Royals | Northwest Arkansas (AA) | Assigned to Northwest Arkansas (AA) |
| Shea Spitzbarth | p | 21.277 | Los Angeles Dodgers | Great Lakes (A) | Assigned to Great Lakes (A) |
| Colby Suggs | P | 24.257 | Miami Marlins | Gulf Coast Marlins (Rk) | Assigned to Gulf Coast Marlins (Rk) |
| Nick Torres | OF | 23.008 | San Diego Padres | El Paso (AAA) | Assigned to El Paso (AAA) |
| Luis Urias | SS | 19.035 | San Diego Padres | El Paso (AAA) | Assigned to El Paso (AAA) |
| Joe Venturino | 2b | 21.355 | Seattle Mariners | Everett (A-) | Assigned to Everett (A-) |
| Ryan Webb | RP | 30.153 | Chicago White Sox | Charlotte (AAA) | Signed to Minor League Contract |
| Garrett Weber | SS-2B | 27.101 | Miami Marlins | New Orleans (AAA) | Assigned to New Orleans (AAA) |
| Alex Winkelman | p | 22.150 | Houston Astros | Gulf Coast Astros (Rk) | Assigned to Gulf Coast Astros (Rk) |
| Trent Woodward | C | 24.155 | Houston Astros | Lancaster (A+) | Activated from disabled list |
| Matt Wotherspoon | P | 24.276 | New York Yankees | Scranton/Wilkes-Barre (AAA) | Assigned to Scranton/Wilkes-Barre (AAA) |
| Miguel Yajure | p | 18.068 | New York Yankees | Gulf Coast Yankees (Rk) | Assigned to Gulf Coast Yankees (Rk) |
| Josh Zeid | RP | 29.106 | New York Mets | Las Vegas (AAA) | Assigned to Las Vegas (AAA) |
| Chris McDonald | p | 21.274 | Pittsburgh Pirates | Gulf Coast Pirates (Rk) | Signed as undrafted free agent (Hillsdale) |
| Evan Piechota | p | 22.262 | Pittsburgh Pirates | Gulf Coast Pirates (Rk) | Signed as undrafted free agent (Madonna) |
| Jeremy Newton | p | 23.037 | Milwaukee Brewers | Arizona Brewers (Rk) | Signed as undrafted free agent (British Columbia) |
| Collin Radack | OF | 24.100 | | | Announced retirement |
| Thomas Hatch | p | 21.282 | Chicago Cubs | Chicago Cubs (MLB) | Signed out of draft (Oklahoma State) |
