| Todd Redmond | RP | 30.047 | Toronto Blue Jays | Toronto Blue Jays (MLB) | Designated for Assignment |
| Dan Straily | SP | 26.214 | Houston Astros | Houston Astros (MLB) | Recalled from Fresno (AAA) |
| Justin Germano | P | 32.331 | | | Released by Mariners |
| Rafael Perez | P | 33.049 | | | Released by Mariners |
| Matt Cain | SP | 30.275 | San Francisco Giants | San Francisco Giants (MLB) | Activated from DL |
| Tim Lincecum | SP | 31.018 | San Francisco Giants | San Francisco Giants (MLB) | DL-15 Right forearm contusion |
| Trevor Cahill | SP-RP | 27.124 | Los Angeles Dodgers | Los Angeles Dodgers (MLB) | Signed to Minor League Contract |
| Brandon League | P | 32.109 | Los Angeles Dodgers | Los Angeles Dodgers (MLB) | Activated from DL and designated for assignment |
| Rafael Ynoa | LF | 27.331 | Colorado Rockies | Albuquerque (AAA) | Assigned to Albuquerque (AAA) |
| Drew Stubbs | LF | 30.272 | Colorado Rockies | Colorado Rockies (MLB) | Recalled from Albuquerque (AAA) |
| Jose Fernandez | SP | 22.337 | Miami Marlins | Miami Marlins (MLB) | Activated from DL |
| Xavier Avery | cf | 25.183 | | | Released by Tigers |
| Aaron Harang | SP | 37.055 | Philadelphia Phillies | Philadelphia Phillies (MLB) | DL-15 Plantar fasciitis |
| Chad Billingsley | SP | 30.339 | Philadelphia Phillies | Philadelphia Phillies (MLB) | Activated from DL |
| Chris Volstad | RP | 28.283 | Pittsburgh Pirates | Pittsburgh Pirates (MLB) | Outrighted to minors |
| Matt Boyd | SP | 24.151 | Toronto Blue Jays | Buffalo (AAA) | Assigned to Buffalo (AAA) |
| Steven Tolleson | SS | 31.245 | Toronto Blue Jays | Buffalo (AAA) | Outrighted to minors |
| Ryan Hanigan | C | 34.321 | Boston Red Sox | Boston Red Sox (MLB) | Activated from DL |
| Jonathan Aro | RP | 24.266 | Boston Red Sox | Pawtucket (AAA) | Assigned to Pawtucket (AAA) |
| Chris Perez | CL | 30.002 | Baltimore Orioles | Baltimore Orioles (MLB) | Signed to Minor League Contract |
| Kevin Gausman | SP | 24.178 | Baltimore Orioles | Baltimore Orioles (MLB) | Recalled from Norfolk (AAA) |
| Archie Bradley | P | 22.327 | Arizona Diamondbacks | Arizona Diamondbacks (MLB) | Activated from DL |
| Daniel Murphy | 2B | 30.093 | New York Mets | New York Mets (MLB) | Activated from DL |
| Joba Chamberlain | RP | 29.283 | Detroit Tigers | Detroit Tigers (MLB) | Designated for Assignment |
| Tom Gorzelanny | RP | 32.356 | Detroit Tigers | Detroit Tigers (MLB) | Designated for Assignment |
| Jeff Ferrell | RP | 24.222 | Detroit Tigers | Detroit Tigers (MLB) | Contract purchased from minors |
| Drew Verhagen | RP | 24.254 | Detroit Tigers | Detroit Tigers (MLB) | Recalled from Erie (AA) |
| Dusty Coleman | 3B | 28.074 | Kansas City Royals | Kansas City Royals (MLB) | Contract purchased from minors |
| Christian Colon | SS | 26.050 | Kansas City Royals | Northwest Arkansas (AA) | Assigned to Northwest Arkansas (AA) |
| Carlos Beltran | RF | 38.070 | New York Yankees | New York Yankees (MLB) | DL-15 Oblique strain |
| Ramon Flores | RF | 23.099 | New York Yankees | New York Yankees (MLB) | Recalled from Scranton/Wilkes-Barre (AAA) |
| Taylor Dugas | OF | 25.200 | New York Yankees | Scranton/Wilkes-Barre (AAA) | Assigned to Scranton/Wilkes-Barre (AAA) |
| Gregorio Petit | 3B | 30.205 | New York Yankees | New York Yankees (MLB) | Recalled from Scranton/Wilkes-Barre (AAA) |
| Shane Robinson | LF | 30.246 | Minnesota Twins | Minnesota Twins (MLB) | Placed on restricted list for family matter |
| Aaron Hicks | CF | 25.274 | Minnesota Twins | Minnesota Twins (MLB) | Activated from DL |
| Felix Doubront | SP | 27.254 | Toronto Blue Jays | Toronto Blue Jays (MLB) | Contract purchased from minors |
| Ryan Tepera | RP | 27.243 | Toronto Blue Jays | Toronto Blue Jays (MLB) | Recalled from Buffalo (AAA) |
| Tyler Cravy | SP | 25.355 | Milwaukee Brewers | Milwaukee Brewers (MLB) | Recalled from Colorado Springs (AAA) |
| David Goforth | P | 26.265 | Milwaukee Brewers | Milwaukee Brewers (MLB) | Recalled from Colorado Springs (AAA) |
| Corey Knebel | RP | 23.220 | Milwaukee Brewers | Colorado Springs (AAA) | Assigned to Colorado Springs (AAA) |
| Jason Rogers | 1B | 27.112 | Milwaukee Brewers | Colorado Springs (AAA) | Assigned to Colorado Springs (AAA) |
| Garrett Fulenchek | P | 19.026 | Tampa Bay Rays | Tampa Bay Rays (MLB) | Traded from Braves to Rays for Intl bonus slots |
| Manuel Rondon | p | 20.118 | Chicago Cubs | Chicago Cubs (MLB) | Traded from Angels with Intl Bonus Slot to Cubs for Rafael Lopez |
| Raffy Lopez | C | 27.275 | Los Angeles Angels | Los Angeles Angels (MLB) | Traded from Cubs to Angels for Manny Rondon and Intl bonus slot |
| Alex Avila | C | 28.155 | Detroit Tigers | Detroit Tigers (MLB) | Activated from DL |
| Bryan Holaday | C | 27.227 | Detroit Tigers | Toledo (AAA) | Assigned to Toledo (AAA) |
| Tommy Pham | CF-LF | 27.117 | St. Louis Cardinals | St. Louis Cardinals (MLB) | Recalled from Memphis (AAA) |
| Tim Cooney | SP | 24.196 | St. Louis Cardinals | Memphis (AAA) | Assigned to Memphis (AAA) |
| Mike Ahmed | IF-P | 23.165 | Los Angeles Dodgers | Great Lakes (A) | Activated from disabled list |
| Dean Aldridge | P | 20.339 | Detroit Tigers | Gulf Coast Tigers (East) (Rk) | Assigned to Gulf Coast Tigers (Rk) |
| Erisbel Arruebarrena | SS | 25.100 | Los Angeles Dodgers | Rancho Cucamonga (A+) | Assigned to Rancho Cucamonga (A+) |
| Xavier Avery | cf | 25.183 | San Francisco Giants | Sacramento (AAA) | Signed to Minor League Contract |
| Rodrigo Ayarza | of | 20.133 | Houston Astros | Gulf Coast Astros (Rk) | Assigned to Gulf Coast Astros (Rk) |
| Dan Barnes | P | 25.255 | Toronto Blue Jays | New Hampshire (AA) | Activated from disabled list |
| Andrew Bellatti | RP | 23.333 | Tampa Bay Rays | Charlotte (A+) | Assigned to Charlotte (A+) for rehab |
| Patrick Biondi | OF | 24.175 | New York Mets | Savannah (A) | Activated from disabled list |
| Leury Bonilla | 3B-2B | 30.145 | Seattle Mariners | Tacoma (AAA) | Activated from disabled list |
| Ronald Bueno | | 22.272 | Cincinnati Reds | Daytona (A+) | Assigned to Daytona (A+) |
| Matt Buschmann | P | 31.141 | Cincinnati Reds | Louisville (AAA) | Assigned to Louisville (AAA) |
| Jose Casilla | P | 26.043 | San Francisco Giants | Richmond (AA) | Activated from disabled list |
| Luis Cessa | P | 23.069 | New York Mets | Las Vegas (AAA) | Assigned to Las Vegas (AAA) |
| Yonny Chirinos | P | 21.189 | Tampa Bay Rays | Bowling Green (A) | Assigned to Bowling Green (A) |
| Nick Christiani | RP | 27.352 | Cincinnati Reds | Pensacola (AA) | Assigned to Pensacola (AA) |
| Christian Colon | SS | 26.050 | Kansas City Royals | Omaha (AAA) | Assigned to Omaha (AAA) |
| Zach Cone | CF | 25.201 | Texas Rangers | Frisco (AA) | Assigned to Frisco (AA) |
| Matt Crouse | P | 25.002 | Detroit Tigers | Erie (AA) | Assigned to Erie (AA) |
| Jordan DeLorenzo | P | 22.298 | St. Louis Cardinals | Gulf Coast Cardinals (Rk) | Assigned to Gulf Coast Cardinals (Rk) |
| Caleb Dirks | P | 22.024 | Los Angeles Dodgers | Rancho Cucamonga (A+) | Assigned to Rancho Cucamonga (A+) |
| Edwin Fierro | P | 21.307 | Tampa Bay Rays | Bowling Green (A) | Assigned to Bowling Green (A) |
| Conor Fisk | P | 23.090 | Toronto Blue Jays | Lansing (A) | Assigned to Lansing (A) |
| Michael Gibbons | p | 22.070 | New York Mets | Binghamton (AA) | Assigned to Binghamton (AA) |
| Bradin Hagens | P | 26.052 | Tampa Bay Rays | Durham (AAA) | Assigned to Durham (AAA) |
| Cody Hamlin | p | 22.144 | New York Yankees | Staten Island (A-) | Assigned to Staten Island (A-) |
| Jeremy Hazelbaker | CF-RF | 27.324 | St. Louis Cardinals | Memphis (AAA) | Assigned to Memphis (AAA) |
| Gabe Hemmer | P | 25.011 | Detroit Tigers | Lakeland (A+) | Assigned to Lakeland (A+) |
| Zach Hoffpauir | of | 21.285 | Arizona Diamondbacks | Hillsboro (A-) | Assigned to Hillsboro (A-) |
| Clay Holmes | P | 22.098 | Pittsburgh Pirates | Bradenton (A+) | Assigned to Bradenton (A+) |
| Jason Hoppe | P | 23.020 | Los Angeles Angels | Burlington (A) | Assigned to Burlington (A) |
| Eudis Idrogo | p | 20.027 | Detroit Tigers | Gulf Coast Tigers (East) (Rk) | Assigned to Gulf Coast Tigers (Rk) |
| Juan Jaime | P | 27.336 | Los Angeles Dodgers | Ogden (Rk) | Assigned to Ogden (Rk) |
| John Jaso | c | 31.288 | Tampa Bay Rays | Charlotte (A+) | Assigned to Charlotte (A+) for rehab |
| Michael Katz | IF | 22.331 | New York Mets | Savannah (A) | Assigned to Savannah (A) |
| Phillip Kish | p | 25.307 | Toronto Blue Jays | Lansing (A) | Activated from disabled list |
| Bobby Korecky | P | 35.291 | Toronto Blue Jays | Buffalo (AAA) | Activated from disabled list |
| Erik Kratz | c | 35.018 | Seattle Mariners | Tacoma (AAA) | Signed to Minor League Contract |
| Yorman Landa | P | 21.022 | Minnesota Twins | Cedar Rapids (A) | Assigned to Cedar Rapids (A) |
| Tim Locastro | SS | 22.354 | Los Angeles Dodgers | Rancho Cucamonga (A+) | Assigned to Rancho Cucamonga (A+) |
| Williams Louico | P | 25.084 | Baltimore Orioles | Frederick (A+) | Activated from disabled list |
| Vimael Machin | ss | 21.281 | Chicago Cubs | South Bend (A) | Assigned to South Bend (A) |
| Cody Martin | P | 25.302 | Oakland Athletics | Nashville (AAA) | Assigned to Nashville (AAA) |
| Trey Masek | P | 23.176 | Chicago Cubs | Eugene (A-) | Assigned to Eugene (A-) |
| Kris Medlen | SP | 29.269 | Kansas City Royals | Omaha (AAA) | Assigned to Omaha (AAA) for rehab |
| Melvin Mercedes | P | 24.243 | Detroit Tigers | Toledo (AAA) | Assigned to Toledo (AAA) |
| Jose Mesa | P | 21.324 | New York Yankees | Gulf Coast Yankees (Rk) | Assigned to Gulf Coast Yankees (Rk) |
| Hoby Milner | P | 24.171 | Philadelphia Phillies | Reading (AA) | Assigned to Reading (AA) |
| Ariel Miranda | p | 26.174 | Baltimore Orioles | Frederick (A+) | Assigned to Frederick (A+) |
| Robert Morey | P | 26.218 | Miami Marlins | New Orleans (AAA) | Activated from disabled list |
| Ty Morrison | CF | 24.346 | Tampa Bay Rays | Charlotte (A+) | Assigned to Charlotte (A+) |
| Casey Mulholland | p | 23.199 | Los Angeles Dodgers | Ogden (Rk) | Assigned to Ogden (Rk) |
| Jairo Munoz | P | 23.326 | Philadelphia Phillies | Gulf Coast Phillies (Rk) | Assigned to Gulf Coast Phillies (Rk) |
| Chris O'Brien | C | 25.344 | Baltimore Orioles | Bowie (AA) | Activated from disabled list |
| Philip Pohl | C | 24.346 | Colorado Rockies | New Britain (AA) | Traded from Athletics to Rockies for cash |
| John Polonius | SS | 24.171 | San Francisco Giants | San Jose (A+) | Activated from disabled list |
| Curt Powell | IF | 24.064 | Detroit Tigers | Erie (AA) | Activated from disabled list |
| Edwin Quirarte | P | 28.195 | San Francisco Giants | Richmond (AA) | Activated from disabled list |
| Natanael Ramos | C | 22.014 | New York Mets | Savannah (A) | Assigned to Savannah (A) |
| Jorge Reyes | P | 27.209 | Atlanta Braves | Gwinnett (AAA) | Assigned to Gwinnett (AAA) |
| David Richardson | P | 24.153 | Baltimore Orioles | Gulf Coast Orioles (Rk) | Assigned to Gulf Coast Orioles (Rk) |
| Austin Ross | P | 26.325 | Milwaukee Brewers | Colorado Springs (AAA) | Assigned to Colorado Springs (AAA) |
| Adderling Ruiz | | 24.061 | Washington Nationals | Potomac (A+) | Assigned to Potomac (A+) |
| Alexander Simon | 1B | 22.278 | Chicago White Sox | Charlotte (AAA) | Assigned to Charlotte (AAA) |
| Slade Smith | P | 24.280 | Detroit Tigers | Erie (AA) | Assigned to Erie (AA) |
| Robert Stephenson | P | 22.129 | Cincinnati Reds | Louisville (AAA) | Assigned to Louisville (AAA) |
| Cory Thompson | SS | 20.283 | Cincinnati Reds | Dayton (A) | Assigned to Dayton (A) |
| Brandon Trinkwon | IF | 23.095 | Los Angeles Dodgers | Tulsa (AA) | Assigned to Tulsa (AA) |
| Andrew Velazquez | SS | 20.354 | Tampa Bay Rays | Charlotte (A+) | Assigned to Charlotte (A+) |
| Jose Velez | P | 25.301 | Miami Marlins | Greensboro (A) | Signed to Minor League Contract |
| Arodys Vizcaino | P | 24.232 | Atlanta Braves | Gwinnett (AAA) | Assigned to Gwinnett (AAA) |
| Chris Volstad | RP | 28.283 | Pittsburgh Pirates | Indianapolis (AAA) | Assigned to Indianapolis (AAA) |
| Sutton Whiting | 2b | 23.051 | Chicago Cubs | Eugene (A-) | Assigned to Eugene (A-) |
| Brad Wieck | P | 23.263 | San Diego Padres | Lake Elsinore (A+) | Assigned to Lake Elsinore (A+) |
| Bryant Aragon | c | 26.084 | San Diego Padres | Arizona Padres (Rk) | Assigned to AZL Padres (Rk) |
| Blake Beavan | RP | 26.167 | | | Released by Diamondbacks |
