| Alex Meyer | RP | 25.174 | Minnesota Twins | Minnesota Twins (MLB) | Recalled from Rochester (AAA) |
| Kristopher Negron | PH | 29.145 | Cincinnati Reds | Louisville (AAA) | Assigned to Louisville (AAA) |
| Aroldis Chapman | RP | 27.119 | Cincinnati Reds | Cincinnati Reds (MLB) | Reinstated from Paternity Leave |
| Vincent Mazzaro | RP | 28.272 | Miami Marlins | Miami Marlins (MLB) | Designated for Assignment |
| Jarred Cosart | RP | 25.032 | Miami Marlins | Miami Marlins (MLB) | Activated from DL |
| Bruce Rondon | RP | 24.199 | Detroit Tigers | Detroit Tigers (MLB) | Recalled from Toledo (AAA) |
| Jeff Bianchi | 2b-3b | 28.264 | Boston Red Sox | Boston Red Sox (MLB) | Outrighted to minors |
| Lance Lynn | SP | 28.045 | St. Louis Cardinals | St. Louis Cardinals (MLB) | Activated from DL |
| Dustin Pedroia | 2B | 31.314 | Boston Red Sox | Boston Red Sox (MLB) | DL-15 Right hamstring tightness |
| Jonathan Aro | RP | 24.259 | Boston Red Sox | Boston Red Sox (MLB) | Contract purchased from minors |
| Miguel Gonzalez | SP | 31.030 | Baltimore Orioles | Baltimore Orioles (MLB) | Activated from DL |
| Spencer Patton | RP | 27.127 | Texas Rangers | Texas Rangers (MLB) | Recalled from Round Rock (AAA) |
| Michael Choice | RF | 25.228 | Texas Rangers | Round Rock (AAA) | Assigned to Round Rock (AAA) |
| Erik Kratz | c | 35.011 | Boston Red Sox | Boston Red Sox (MLB) | Designated for Assignment |
| Jackie Bradley | RF | 25.068 | Boston Red Sox | Boston Red Sox (MLB) | Recalled from Pawtucket (AAA) |
| Gregorio Petit | 2B | 30.198 | New York Yankees | New York Yankees (MLB) | Recalled from Scranton/Wilkes-Barre (AAA) |
| Stephen Drew | 2B | 32.102 | New York Yankees | New York Yankees (MLB) | Reinstated from Paternity Leave |
| Byron Buxton | CF | 21.190 | Minnesota Twins | Minnesota Twins (MLB) | DL-15 Left thumb sprain |
| Danny Santana | SS-CF | 24.231 | Minnesota Twins | Minnesota Twins (MLB) | Recalled from Rochester (AAA) |
| Chad Qualls | RP | 36.313 | Houston Astros | Houston Astros (MLB) | DL-15 Pinched nerve in neck |
| Jonathan Singleton | 1B-DH | 23.282 | Houston Astros | Houston Astros (MLB) | Recalled from Fresno (AAA) |
| Anthony Rendon | 2B | 25.020 | Washington Nationals | Washington Nationals (MLB) | DL-15 Left quadriceps strain |
| Emmanuel Burriss | 2B | 30.160 | Washington Nationals | Washington Nationals (MLB) | Contract purchased from minors |
| Devon Travis | 2B | 24.125 | Toronto Blue Jays | Toronto Blue Jays (MLB) | Activated from DL |
| Munenori Kawasaki | 2B | 34.023 | Toronto Blue Jays | Buffalo (AAA) | Assigned to Buffalo (AAA) |
| Pedro Baez | RP | 27.107 | Los Angeles Dodgers | Los Angeles Dodgers (MLB) | Activated from DL |
| Ian Thomas | RP | 28.067 | Los Angeles Dodgers | Oklahoma City (AAA) | Assigned to Oklahoma City (AAA) |
| Martires Arias | P | 24.228 | New York Mets | Savannah (A) | Activated from disabled list |
| Andrew Bailey | RP | 31.026 | New York Yankees | Tampa (A+) | Assigned to Tampa (A+) |
| Matt Beaty | if | 22.059 | Los Angeles Dodgers | Great Lakes (A) | Assigned to Great Lakes (A) |
| Jeff Bianchi | SS | 28.264 | Boston Red Sox | Pawtucket (AAA) | Assigned to Pawtucket (AAA) |
| Scott Brattvet | P | 23.341 | Cincinnati Reds | Daytona (A+) | Assigned to Daytona (A+) |
| Travis Brewster | OF | 23.157 | Miami Marlins | Greensboro (A) | Assigned to Greensboro (A) |
| Endrys Briceno | P | 23.140 | Detroit Tigers | Gulf Coast Tigers (East) (Rk) | Activated from disabled list |
| Wil Browning | P | 26.291 | Toronto Blue Jays | New Hampshire (AA) | Assigned to New Hampshire (AA) |
| Yordy Cabrera | SS | 24.296 | Miami Marlins | Gulf Coast Marlins (Rk) | Assigned to Gulf Coast Marlins (Rk) |
| Rolando Calvo | p | 22.009 | New York Yankees | Gulf Coast Yankees 2 (Rk) | Assigned to Gulf Coast Yankees 2 (Rk) |
| James Campbell | P | 23.280 | Los Angeles Dodgers | Great Lakes (A) | Assigned to Great Lakes (A) |
| Wilkin Castillo | C | 31.025 | Pittsburgh Pirates | Indianapolis (AAA) | Activated from disabled list |
| Miguel Castro | P | 20.184 | Toronto Blue Jays | Dunedin (A+) | Activated from disabled list |
| Ruben Castro | C | 18.351 | Houston Astros | Gulf Coast Astros (Rk) | Assigned to Gulf Coast Astros (Rk) |
| Joe Chavez | ss | 22.000 | Miami Marlins | Batavia (A-) | Assigned to Batavia (A-) |
| Juan Ciriaco | SS-LF | 31.316 | San Francisco Giants | Richmond (AA) | Assigned to Richmond (AA) |
| Hunter Cole | OF | 22.266 | San Francisco Giants | Richmond (AA) | Assigned to Richmond (AA) |
| Boomer Collins | IF | 26.013 | Toronto Blue Jays | Lansing (A) | Activated from disabled list |
| Jace Conrad | 2B | 22.193 | Tampa Bay Rays | Charlotte (A+) | Assigned to Charlotte (A+) |
| Luke Curtis | P | 23.178 | Milwaukee Brewers | Wisconsin (A) | Activated from disabled list |
| Michael Danner | OF | 23.282 | Chicago White Sox | Kannapolis (A) | Activated from disabled list |
| James Farris | P | 23.083 | Chicago Cubs | Myrtle Beach (A+) | Assigned to Myrtle Beach (A+) |
| Roemon Fields | OF | 24.210 | Toronto Blue Jays | New Hampshire (AA) | Assigned to New Hampshire (AA) |
| Raymel Flores | SS | 20.277 | Arizona Diamondbacks | Missoula (Rk) | Assigned to Missoula (Rk) |
| Cameron Flynn | OF-P | 25.122 | Miami Marlins | Jupiter (A+) | Assigned to Jupiter (A+) |
| Dustin Fowler | CF | 20.179 | New York Yankees | Tampa (A+) | Assigned to Tampa (A+) |
| Dallas Gallant | P | 26.152 | Minnesota Twins | Fort Myers (A+) | Assigned to Fort Myers (A+) |
| Wilson Garcia | C | 21.166 | Philadelphia Phillies | Clearwater (A+) | Assigned to Clearwater (A+) |
| Tyler Glasnow | P | 21.307 | Pittsburgh Pirates | Altoona (AA) | Assigned to Altoona (AA) |
| Hector Guevara | 2B | 23.263 | Tampa Bay Rays | Princeton (Rk) | Assigned to Princeton (Rk) |
| Matt Hall | p | 21.338 | Detroit Tigers | Connecticut (A-) | Assigned to Connecticut (A-) |
| Cody Hamlin | p | 22.137 | New York Yankees | Gulf Coast Yankees 2 (Rk) | Assigned to Gulf Coast Yankees 2 (Rk) |
| Jordan Harrison | P | 24.078 | Tampa Bay Rays | Bowling Green (A) | Assigned to Bowling Green (A) |
| Kevin Herget | P | 24.084 | St. Louis Cardinals | Palm Beach (A+) | Assigned to Palm Beach (A+) |
| Brent Honeywell | P | 20.087 | Tampa Bay Rays | Charlotte (A+) | Assigned to Charlotte (A+) |
| Bryan Hudson | OF | 20.136 | Boston Red Sox | Greenville (A) | Assigned to Greenville (A) |
| Zach Kapstein | 1B | 23.029 | Boston Red Sox | Salem (A+) | Assigned to Salem (A+) |
| Braulio Lara | P | 26.188 | San Francisco Giants | Richmond (AA) | Assigned to Richmond (AA) |
| Patrick Leyland | C | 23.259 | Seattle Mariners | Clinton (A) | Assigned to Clinton (A) |
| Brad Lincoln | RP | 30.032 | Pittsburgh Pirates | Indianapolis (AAA) | Activated from disabled list |
| Alexis Maldonado | SS | 24.014 | Toronto Blue Jays | Lansing (A) | Assigned to Lansing (A) |
| Shaun Marcum | SP | 33.194 | Cleveland Indians | Columbus (AAA) | Assigned to Columbus (AAA) |
| Daniel McGrath | P | 20.354 | Boston Red Sox | Gulf Coast Red Sox (Rk) | Activated from disabled list |
| Michael Miller | C | 23.030 | San Diego Padres | Fort Wayne (A) | Assigned to Fort Wayne (A) |
| John Mincone | P | 25.338 | New York Mets | St. Lucie (A+) | Assigned to St. Lucie (A+) |
| Ty Morrison | CF | 24.339 | Tampa Bay Rays | Charlotte (A+) | Assigned to Charlotte (A+) |
| Taylor Munden | ss | 21.354 | Miami Marlins | Greensboro (A) | Assigned to Greensboro (A) |
| Gabriel Noriega | SS-2B | 24.286 | Kansas City Royals | Omaha (AAA) | Activated from disabled list |
| Nefi Ogando | P | 26.023 | Philadelphia Phillies | Lehigh Valley (AAA) | Assigned to Lehigh Valley (AAA) |
| Josh Osich | P | 26.296 | San Francisco Giants | Sacramento (AAA) | Assigned to Sacramento (AAA) |
| Cameron Palmer | p | 23.206 | Los Angeles Dodgers | Great Lakes (A) | Assigned to Great Lakes (A) |
| Andy Parrino | 3B | 29.238 | Oakland Athletics | Nashville (AAA) | Assigned to Nashville (AAA) |
| Bryan Petersen | lf | 29.078 | Milwaukee Brewers | Colorado Springs (AAA) | Activated from disabled list |
| Rohn Pierce | P | 22.156 | Seattle Mariners | Everett (A-) | Assigned to Everett (A-) |
| Boog Powell | OF | 22.163 | Tampa Bay Rays | Durham (AAA) | Assigned to Durham (AAA) |
| Ricardo Rodriguez | P | 22.299 | Texas Rangers | Hickory (A) | Assigned to Hickory (A) |
| Reinier Roibal | P | 26.158 | Philadelphia Phillies | Reading (AA) | Activated from disabled list |
| Joshua Rutledge | 2B | 26.066 | Los Angeles Angels | Arizona Angels (Rk) | Assigned to AZL Angels (Rk) for rehab |
| Eury Sanchez | | 22.230 | San Francisco Giants | Arizona Giants (Rk) | Assigned to Arizona Giants (Rk) |
| Andrew Schwaab | p | 22.138 | New York Yankees | Gulf Coast Yankees 2 (Rk) | Assigned to Gulf Coast Yankees 2 (Rk) |
| Justin Shafer | IF-OF | 22.281 | Toronto Blue Jays | Lansing (A) | Assigned to Lansing (A) |
| Arik Sikula | P | 26.187 | Toronto Blue Jays | Dunedin (A+) | Activated from disabled list |
| Kyle Skipworth | C | 25.117 | Cincinnati Reds | Pensacola (AA) | Activated from disabled list |
| Sean Smedley | C-1B | 24.271 | Tampa Bay Rays | Bowling Green (A) | Assigned to Bowling Green (A) |
| Elliot Soto | SS | 25.309 | Chicago Cubs | Tennessee (AA) | Activated from disabled list |
| Scott Squier | P | 22.282 | Miami Marlins | Batavia (A-) | Assigned to Batavia (A-) |
| Brandon Stenhouse | p | 18.280 | New York Yankees | Gulf Coast Yankees 2 (Rk) | Assigned to Gulf Coast Yankees 2 (Rk) |
| Kelby Tomlinson | SS | 25.010 | San Francisco Giants | Sacramento (AAA) | Assigned to Sacramento (AAA) |
| Nick Tropeano | P | 24.303 | Los Angeles Angels | Arizona Angels (Rk) | Activated from disabled list |
| Trea Turner | SS | 21.361 | Washington Nationals | Syracuse (AAA) | Assigned to Syracuse (AAA) |
| Logan Uxa | OF | 24.152 | Baltimore Orioles | Delmarva (A) | Assigned to Delmarva (A) |
| Angel Villalona | IF | 24.317 | San Francisco Giants | San Jose (A+) | Assigned to San Jose (A+) |
| Josh Wall | RP | 28.156 | Pittsburgh Pirates | Indianapolis (AAA) | Activated from disabled list |
| Nick Williams | P | 23.224 | Miami Marlins | Jupiter (A+) | Assigned to Jupiter (A+) |
| Mac Williamson | OF | 24.346 | San Francisco Giants | Sacramento (AAA) | Assigned to Sacramento (AAA) |
| Kyle Winkler | P | 25.008 | Los Angeles Angels | Arkansas (AA) | Assigned to Arkansas (AA) |
| Tanner Witt | 2b | 24.152 | Baltimore Orioles | Frederick (A+) | Signed to Minor League Contract |
| Casey Sadler | P | 24.348 | Pittsburgh Pirates | Indianapolis (AAA) | DL-7 Injured |
| Denny Bautista | p | 32.246 | | | Released by Red Sox |
| Guilder Rodriguez | SS | 31.338 | Texas Rangers | Frisco (AA) | DL-7 Injured |
| Louis Marson | c | 29.000 | | | Released by Reds |
| Jeremy Farrell | 3B | 28.227 | Chicago White Sox | Birmingham (AA) | DL-7 Injured |
| Mike Thomas | P | 26.171 | Los Angeles Dodgers | Tulsa (AA) | DL-7 Injured |
| Parker Frazier | P | 26.227 | Arizona Diamondbacks | Mobile (AA) | DL-7 Injured |
| Seth Loman | 1B | 29.192 | | | Released by Braves |
| Tyler Webb | P | 24.341 | New York Yankees | Scranton/Wilkes-Barre (AAA) | DL-7 Injured |
| Bobby Wahl | P | 23.097 | Oakland Athletics | Midland (AA) | DL-7 Injured |
| Mike Augliera | P | 25.018 | Boston Red Sox | Portland (AA) | DL-7 Injured |
| Oliver Caraballo | C | 20.305 | Texas Rangers | Frisco (AA) | DL-7 Injured |
| Richard Vargas | P | 24.068 | Seattle Mariners | Jackson (AA) | DL-7 Injured |
| Alex Reyes | P | 20.301 | St. Louis Cardinals | Palm Beach (A+) | DL-7 Shoulder soreness |
| Brandon Martinez | P | 24.213 | | | Released by Dodgers |
| Cody Davis | P | 24.340 | | | Released by Nationals |
| Jeff Soptic | P | 24.079 | San Francisco Giants | San Jose (A+) | DL-7 Injured |
| Jordan Steranka | 3B | 25.224 | Pittsburgh Pirates | Bradenton (A+) | DL-7 Injured |
| Jose Velez | P | 25.294 | | | Released by Twins |
| Juan De La Cruz | C | 21.325 | Cleveland Indians | Lynchburg (A+) | DL-7 Injured |
| Ryan Etsell | P | 23.191 | Los Angeles Angels | Inland Empire (A+) | DL-7 Injured |
| Ryan Ledbetter | P | 23.134 | Texas Rangers | High Desert (A+) | DL-7 Injured |
| Tyler Kinley | P | 24.146 | Miami Marlins | Jupiter (A+) | DL-7 Injured |
| Tyler Palmer | IF-OF | 23.280 | Los Angeles Angels | Inland Empire (A+) | DL-7 Injured |
| Will Anderson | P | 22.304 | St. Louis Cardinals | Palm Beach (A+) | DL-7 Injured |
| Carlos Leal | C | 23.349 | Milwaukee Brewers | Wisconsin (A) | DL-7 Injured |
| Chris Dula | P | 22.324 | Texas Rangers | Hickory (A) | DL-7 Injured |
| K.J. Woods | RF | 19.353 | Miami Marlins | Greensboro (A) | Suspended |
| Tyler Mahle | P | 20.270 | Cincinnati Reds | Dayton (A) | Placed on temporary inactive list |
| Vaughn Bryan | CF | 22.021 | St. Louis Cardinals | Peoria (A) | DL-7 Injured |
| Armando Rivero | P | 27.146 | Chicago Cubs | Iowa (AAA) | Placed on paternity leave |
| Alec Kisena | p | 19.258 | Detroit Tigers | Gulf Coast Tigers (East) (Rk) | Signed out of draft (Edmonds CC) |
| Demarcus Evans | p | 18.247 | Texas Rangers | Arizona Rangers (Rk) | Signed out of draft (Mississippi HS) |
| Max Watt | p | 20.321 | Boston Red Sox | Gulf Coast Red Sox (Rk) | Signed out of draft (Hillsborough) |
| Woody Edwards | of | 20.085 | San Francisco Giants | Arizona Giants (Rk) | Signed out of draft (Gulf Coast CC) |
| Seamus Curran | 1b | 17.293 | Baltimore Orioles | Gulf Coast Orioles (Rk) | Signed out of draft (Massachusetts HS) |
| Sixto Torres | p | 19.087 | New York Mets | Gulf Coast Mets (Rk) | Signed out of draft (Florida HS) |
| Terrance Robertson | of | 18.220 | New York Yankees | Gulf Coast Yankees (Rk) | Signed out of draft (Arizona HS) |
| Yonauris Rodriguez | ss | 18.108 | New York Yankees | Gulf Coast Yankees (Rk) | Assigned to GCL Yankees (Rk) |
| A.J. Kennedy | c | 21.154 | San Diego Padres | Tri-City (A-) | Signed out of draft (Cal State Fullerton) |
| Alex Bregman | ss | 21.088 | Houston Astros | Quad Cities (A) | Signed out of draft (LSU) |
| Andrew Stevenson | of | 21.025 | Washington Nationals | Auburn (A-) | Signed out of draft (LSU) |
| Blake Hickman | c | 21.240 | Chicago White Sox | Arizona White Sox (Rk) | Signed out of draft (Iowa) |
| Bryan Case | c | 22.318 | San Francisco Giants | Arizona Giants (Rk) | Signed out of draft (Oklahoma State) |
| Chris Shaw | 1b | 21.249 | San Francisco Giants | Salem-Keizer (A-) | Signed out of draft (Boston College) |
| Conner Hale | 1b | 22.259 | Seattle Mariners | Everett (A-) | Signed out of draft (LSU) |
| Cory Taylor | p | 21.194 | San Francisco Giants | Salem-Keizer (A-) | Signed out of draft (Dallas Baptist) |
| David Graybill | p | 22.054 | San Francisco Giants | Arizona Giants (Rk) | Signed out of draft (Arizona State) |
| Heath Slatton | p | 21.282 | San Francisco Giants | Arizona Giants (Rk) | Signed out of draft (Middle Tennessee State) |
| Ian Rice | c | 21.311 | Chicago Cubs | Eugene (A-) | Signed out of draft (Houston) |
| Jon Harris | p | 21.253 | Toronto Blue Jays | Vancouver (A-) | Signed out of draft (Missouri State) |
| Jose Vizcaino | ss | 21.082 | San Francisco Giants | Salem-Keizer (A-) | Signed out of draft (Santa Clara) |
| Koda Glover | p | 22.074 | Washington Nationals | Auburn (A-) | Signed out of draft (Oklahoma State) |
| Kyri Washington | of | 20.350 | Boston Red Sox | Gulf Coast Red Sox (Rk) | Signed out of draft (Longwood) |
| Matt Rose | p | 20.328 | Chicago Cubs | Eugene (A-) | Signed out of draft (Georgia State) |
| Matthew Pope | p | 20.356 | San Francisco Giants | Arizona Giants (Rk) | Signed out of draft (Walters State) |
| Robert Strader | p | 21.103 | Baltimore Orioles | Gulf Coast Orioles (Rk) | Signed out of draft (Louisville) |
| Ryan Halstead | p | 23.044 | San Francisco Giants | Salem-Keizer (A-) | Signed out of draft (Indiana) |
| Ryan Meisinger | p | 21.053 | Baltimore Orioles | Gulf Coast Orioles (Rk) | Signed out of draft (Radford) |
| Samm Wiggins | c | 22.179 | Tampa Bay Rays | Gulf Coast Rays (Rk) | Signed as undrafted free agent (Houston Baptist) |
| Taylor Guilbeau | p | 22.045 | Washington Nationals | Gulf Coast Nationals (Rk) | Signed out of draft (Alabama) |
| Taylor Hearn | p | 20.300 | Washington Nationals | Gulf Coast Nationals (Rk) | Signed out of draft (San Jacinto) |
| Anderson Martinez | P | 22.124 | Washington Nationals | Auburn (A-) | DL-7 Injured |
| James Bourque | P | 21.352 | Washington Nationals | Auburn (A-) | DL-7 Injured |
| Joe Watson | P | 22.275 | Texas Rangers | Arizona Rangers (Rk) | Suspended |
| Billy Hamilton | CF | 24.290 | Cincinnati Reds | Cincinnati Reds (MLB) | DL-15 Right shoulder sprain |
| Nick Andros | p | 22.217 | Kansas City Royals | Kansas City Royals (MLB) | Signed as undrafted free agent (Lipscomb) |
