| Alex White | P | 26.219 | Houston Astros | Houston Astros (MLB) | Designated for Assignment |
| Roberto Hernandez | RP | 34.218 | Houston Astros | Houston Astros (MLB) | Contract purchased from minors |
| Erik Goeddel | P | 26.106 | New York Mets | New York Mets (MLB) | Sent to minors |
| Eric Campbell | 3B-1B | 27.362 | New York Mets | New York Mets (MLB) | Sent to minors |
| Clint Robinson | 1B-LF | 30.048 | Washington Nationals | Washington Nationals (MLB) | Contract purchased from minors |
| Matt Tuiasosopo | lf | 28.330 | Chicago White Sox | Chicago White Sox (MLB) | Signed to Minor League Contract |
| Josh Hamilton | dh | 33.319 | Los Angeles Angels | Los Angeles Angels (MLB) | DL-15 Recovery from right shoulder surgery |
| Dan Robertson | RF-CF | 29.187 | Los Angeles Angels | Los Angeles Angels (MLB) | Sent to minors |
| Jeanmar Gomez | RP | 26.185 | Philadelphia Phillies | Philadelphia Phillies (MLB) | Contract purchased from minors |
| Dustin McGowan | RP | 33.012 | Philadelphia Phillies | Philadelphia Phillies (MLB) | Signed to 1-year contract for 2015-2015 ($0m) [Free Agent] |
| Andy Oliver | P | 27.124 | | | Refused minor league assignment, declared free agent |
| Cesar Jimenez | RP | 30.144 | Philadelphia Phillies | Philadelphia Phillies (MLB) | Contract purchased from minors |
| Brad Hand | RP | 25.016 | Miami Marlins | Miami Marlins (MLB) | Sent to minors |
| Mike Foltynewicz | P | 23.181 | Atlanta Braves | Atlanta Braves (MLB) | Sent to minors |
| Mike Minor | SP | 27.101 | Atlanta Braves | Atlanta Braves (MLB) | DL-15 Left rotator cuff inflammation |
| Todd Cunningham | rf | 26.016 | Atlanta Braves | Atlanta Braves (MLB) | Sent to minors |
| Melvin Upton | cf | 30.227 | Atlanta Braves | Atlanta Braves (MLB) | DL-15 Sesamoiditis, left foot |
| Mike Bowden | RP | 28.208 | Baltimore Orioles | Baltimore Orioles (MLB) | Traded from Reds to Orioles for cash considerations |
| Bradin Hagens | P | 25.328 | Tampa Bay Rays | Tampa Bay Rays (MLB) | Traded from Diamondbacks to Rays for cash considerations |
| Jose Pirela | SS | 25.135 | New York Yankees | New York Yankees (MLB) | DL-7 Concussion |
| Gregorio Petit | SS | 30.116 | New York Yankees | New York Yankees (MLB) | Contract purchased from minors |
| Brendan Ryan | ss | 33.010 | New York Yankees | New York Yankees (MLB) | DL-15 Strained right calf |
| Chris Capuano | SP | 35.230 | New York Yankees | New York Yankees (MLB) | DL-15 Strained right quadriceps |
| Ivan Nova | SP | 28.083 | New York Yankees | New York Yankees (MLB) | DL-15 Recovery from right elbow surgery |
| Austin Romine | c | 26.134 | New York Yankees | New York Yankees (MLB) | Designated for Assignment |
| Charlie Morton | SP | 31.145 | Pittsburgh Pirates | Pittsburgh Pirates (MLB) | DL-15 Hip |
| Garrett Richards | SP | 26.313 | Los Angeles Angels | Los Angeles Angels (MLB) | DL-15 Recovery from left knee surgery |
| Tyler Skaggs | SP | 23.267 | Los Angeles Angels | Los Angeles Angels (MLB) | DL-15 Recovery from left elbow surgery |
| Cory Rasmus | RP | 27.151 | Los Angeles Angels | Los Angeles Angels (MLB) | DL-15 Core muscle surgery |
| Jonathan Edwards | P | 27.088 | Texas Rangers | Texas Rangers (MLB) | Sent to minors |
| Alex Claudio | P | 23.065 | Texas Rangers | Texas Rangers (MLB) | Sent to minors |
| Yordano Ventura | P | 23.307 | Kansas City Royals | Kansas City Royals (MLB) | Signed to 5-year contract for 2015-2019 ($23m) [Extension] 0.75--1--3.25--6.25--9.75 Option years for 2020-2021 at $12m each |
| Sean Nolin | SP | 25.100 | Oakland Athletics | Oakland Athletics (MLB) | DL-15 Recovery from bi-lateral core surgery |
| Jarrod Parker | SP | 26.132 | Oakland Athletics | Oakland Athletics (MLB) | DL-15 Recovery from right elbow surgery |
| Sean Doolittle | RP | 28.191 | Oakland Athletics | Oakland Athletics (MLB) | DL-15 Torn left rotator cuff |
| Josh Reddick | rf | 28.045 | Oakland Athletics | Oakland Athletics (MLB) | DL-15 Strained right oblique |
| Nate Freiman | 1b | 28.095 | Oakland Athletics | Oakland Athletics (MLB) | DL-15 Back strain |
| Coco Crisp | cf | 35.156 | Oakland Athletics | Oakland Athletics (MLB) | DL-15 Right elbow surgery |
| Chris Taylor | IF | 24.219 | Seattle Mariners | Seattle Mariners (MLB) | DL-15 Fractured right wrist |
| Tyler Olson | P | 25.185 | Seattle Mariners | Seattle Mariners (MLB) | Contract purchased from minors |
| Gerald Laird | c | 35.144 | Arizona Diamondbacks | Arizona Diamondbacks (MLB) | Contract purchased from minors |
| Jordan Pacheco | c-1B | 29.065 | Arizona Diamondbacks | Arizona Diamondbacks (MLB) | Contract purchased from minors |
| Cody Ross | lf | 34.103 | | | Released by Diamondbacks |
| Bronson Arroyo | SP | 38.040 | Arizona Diamondbacks | Arizona Diamondbacks (MLB) | DL-60 Recovery from right elbow surgery |
| Patrick Corbin | SP | 25.260 | Arizona Diamondbacks | Arizona Diamondbacks (MLB) | DL-15 Recovery from left elbow surgery |
| David Hernandez | RP | 29.327 | Arizona Diamondbacks | Arizona Diamondbacks (MLB) | DL-15 Recovery from right elbow surgery |
| Vidal Nuno | SP | 27.254 | Arizona Diamondbacks | Arizona Diamondbacks (MLB) | Sent to minors |
| Archie Bradley | P | 22.238 | Arizona Diamondbacks | Arizona Diamondbacks (MLB) | Contract purchased from minors |
| Matt Stites | P | 24.312 | Arizona Diamondbacks | Arizona Diamondbacks (MLB) | DL-15 Right elbow pain |
| Barry Enright | SP | 29.006 | | | Released by Dodgers |
| Jim Henderson | RP | 32.166 | Milwaukee Brewers | Milwaukee Brewers (MLB) | DL-15 Recovery from right shoulder surgery |
| Bobby Wilson | C | 31.363 | Tampa Bay Rays | Tampa Bay Rays (MLB) | Contract purchased from minors |
| Curt Casali | C | 26.147 | Tampa Bay Rays | Tampa Bay Rays (MLB) | Sent to minors |
| C.J. Riefenhauser | P | 25.065 | Tampa Bay Rays | Tampa Bay Rays (MLB) | Sent to minors |
| Bruce Rondon | RP | 24.117 | Detroit Tigers | Detroit Tigers (MLB) | DL-15 Right biceps tendinitis |
| Jordan Danks | rf | 28.241 | Philadelphia Phillies | Philadelphia Phillies (MLB) | Sent to minors |
| Jeff Francoeur | RF | 31.088 | Philadelphia Phillies | Philadelphia Phillies (MLB) | Contract purchased from minors |
| Jonathan Pettibone | SP | 24.260 | Philadelphia Phillies | Philadelphia Phillies (MLB) | DL-15 Recovery from right shoulder surgery |
| Chad Billingsley | SP | 30.250 | Philadelphia Phillies | Philadelphia Phillies (MLB) | Recovery from right elbow surgery |
| Andres Blanco | 2B | 30.359 | Philadelphia Phillies | Philadelphia Phillies (MLB) | Contract purchased from minors |
| Mario Hollands | P | 26.222 | Philadelphia Phillies | Philadelphia Phillies (MLB) | DL-60 Strained flexor tendon, left forearm. Tommy John Surgery |
| Don Kelly | 3b-lf | 35.050 | Miami Marlins | Miami Marlins (MLB) | Contract purchased from minors |
| Aaron Crow | RP | 28.145 | Miami Marlins | Miami Marlins (MLB) | DL-15 Right elbow sprain |
| Jose Fernandez | SP | 22.248 | Miami Marlins | Miami Marlins (MLB) | Recovery from right elbow surgery |
| Anthony Swarzak | RP | 29.207 | Cleveland Indians | Cleveland Indians (MLB) | Contract purchased from minors |
| Josh Tomlin | P | 30.168 | Cleveland Indians | Cleveland Indians (MLB) | DL-15 Right shoulder surgery |
| Gavin Floyd | SP | 32.068 | Cleveland Indians | Cleveland Indians (MLB) | DL-60 Right elbow surgery |
| Zach Walters | SS | 25.212 | Cleveland Indians | Cleveland Indians (MLB) | DL-15 Strained right oblique |
| Nick Swisher | 1b | 34.131 | Cleveland Indians | Cleveland Indians (MLB) | DL-15 Recovery from bi-lateral knee surgery |
| Edgmer Escalona | RP | 28.181 | | | Released by Giants |
| Enrique Hernandez | LF | 23.225 | Los Angeles Dodgers | Los Angeles Dodgers (MLB) | Sent to minors |
| Chris Heisey | lf | 30.112 | Los Angeles Dodgers | Los Angeles Dodgers (MLB) | Sent to minors |
| Rudy Owens | P | 27.109 | Los Angeles Dodgers | Los Angeles Dodgers (MLB) | Traded from Athletics to Dodgers for cash considerations |
| J.J. Hardy | ss | 32.229 | Baltimore Orioles | Baltimore Orioles (MLB) | DL-15 Left shoulder strain |
| T.J. McFarland | RP | 25.301 | Baltimore Orioles | Baltimore Orioles (MLB) | Sent to minors |
| David Lough | rf | 29.075 | Baltimore Orioles | Baltimore Orioles (MLB) | DL-15 Strained left hamstring |
| Jimmy Paredes | 2b | 26.131 | Baltimore Orioles | Baltimore Orioles (MLB) | DL-15 Lower back strain |
| Matt Wieters | c | 28.319 | Baltimore Orioles | Baltimore Orioles (MLB) | DL-15 Recovery from right elbow surgery |
| Miguel Castro | P | 20.102 | Toronto Blue Jays | Toronto Blue Jays (MLB) | Contract purchased from minors |
| Roberto Osuna | RP | 20.057 | Toronto Blue Jays | Toronto Blue Jays (MLB) | Contract purchased from minors |
| Marcus Stroman | P | 23.340 | Toronto Blue Jays | Toronto Blue Jays (MLB) | DL-60 Torn ACL, left knee |
| Michael Saunders | LF-cf | 28.137 | Toronto Blue Jays | Toronto Blue Jays (MLB) | DL-15 Recovery from left knee surgery |
| Maicer Izturis | ss-2b | 34.205 | Toronto Blue Jays | Toronto Blue Jays (MLB) | DL-15 Right groin strain |
| Denard Span | cf | 31.038 | Washington Nationals | Washington Nationals (MLB) | DL-15 Right core muscle surgery |
| Dan Uggla | 2B | 35.025 | Washington Nationals | Washington Nationals (MLB) | Contract purchased from minors |
| Anthony Rendon | 2b | 24.303 | Washington Nationals | Washington Nationals (MLB) | DL-15 Sprained MCL, left knee |
| Jayson Werth | rf | 35.321 | Washington Nationals | Washington Nationals (MLB) | DL-15 Recovery from right shoulder surgery |
| Reed Johnson | lf | 38.118 | Washington Nationals | Washington Nationals (MLB) | Contract purchased from minors |
| Nate McLouth | lf | 33.159 | Washington Nationals | Washington Nationals (MLB) | DL-15 Right shoulder surgery |
| Erik Davis | RP | 28.179 | Washington Nationals | Washington Nationals (MLB) | DL-15 Recovery from right elbow surgery |
| Casey Janssen | RP | 33.200 | Washington Nationals | Washington Nationals (MLB) | DL-15 Right rotator cuff tendinitis |
| Jake Petricka | RP | 26.304 | Chicago White Sox | Chicago White Sox (MLB) | DL-15 Strained right forearm |
| Eric Surkamp | SP | 27.264 | Chicago White Sox | Chicago White Sox (MLB) | DL-15 Strained upper back |
| Matt Albers | RP | 32.075 | Chicago White Sox | Chicago White Sox (MLB) | Contract purchased from minors |
| Chris Sale | SP | 26.006 | Chicago White Sox | Chicago White Sox (MLB) | DL-15 Fractured right foot |
| Micah Johnson | IF-OF | 24.108 | Chicago White Sox | Chicago White Sox (MLB) | Contract purchased from minors |
| Geovany Soto | C | 32.075 | Chicago White Sox | Chicago White Sox (MLB) | Contract purchased from minors |
| Lisalverto Bonilla | P | 24.291 | Texas Rangers | Texas Rangers (MLB) | DL-15 Right elbow impingement |
| Keone Kela | RP | 21.354 | Texas Rangers | Texas Rangers (MLB) | Contract purchased from minors |
| Yu Darvish | SP | 28.232 | Texas Rangers | Texas Rangers (MLB) | DL-60 Right elbow surgery |
| Matt Harrison | SP | 29.232 | Texas Rangers | Texas Rangers (MLB) | DL-15 Recovery from back surgery |
| Tanner Scheppers | RP | 28.078 | Texas Rangers | Texas Rangers (MLB) | DL-15 Sprained right ankle |
| Anthony Bass | RP | 27.156 | Texas Rangers | Texas Rangers (MLB) | Contract purchased from minors |
| Sam Freeman | RP | 27.286 | Texas Rangers | Texas Rangers (MLB) | Designated for Assignment |
| Kyuji Fujikawa | RP | 34.258 | Texas Rangers | Texas Rangers (MLB) | DL-15 Right groin strain |
| Ryan Madson | RP | 34.220 | Kansas City Royals | Kansas City Royals (MLB) | Contract purchased from minors |
| Luke Hochevar | RP | 31.203 | Kansas City Royals | Kansas City Royals (MLB) | DL-15 Recovery from right elbow surgery |
| Tim Collins | RP | 25.227 | Kansas City Royals | Kansas City Royals (MLB) | DL-15 Left elbow surgery |
| Franklin Morales | RP | 29.071 | Kansas City Royals | Kansas City Royals (MLB) | Contract purchased from minors |
| Brian Flynn | P | 24.351 | Kansas City Royals | Kansas City Royals (MLB) | Sent to minors |
| Corey Kluber | SP | 28.360 | Cleveland Indians | Cleveland Indians (MLB) | Signed to 5-year contract for 2015-2019 ($38.5m) [Extension] 1--4.5--7.5--10.5--13 Club options for 2020-2021 at 13.5--14. Options can be escalated and buyout is $1m |
| Erik Cordier | P | 29.039 | San Francisco Giants | San Francisco Giants (MLB) | DL-15 Right forearm strain |
| Hunter Pence | rf | 31.358 | San Francisco Giants | San Francisco Giants (MLB) | DL-15 Broken left forearm |
| Travis Ishikawa | 1b | 31.194 | San Francisco Giants | San Francisco Giants (MLB) | DL-15 Lower back strain |
| Ryan Sweeney | CF | 30.044 | Chicago Cubs | Chicago Cubs (MLB) | Designated for Assignment |
| Chris Denorfia | rf-lf | 34.264 | Chicago Cubs | Chicago Cubs (MLB) | DL-15 Mild left hamstring strain |
| Tsuyoshi Wada | P | 34.043 | Chicago Cubs | Chicago Cubs (MLB) | DL-15 Mild left groin strain |
| Jacob Turner | SP | 23.320 | Chicago Cubs | Chicago Cubs (MLB) | DL-15 Strained flexor tendon, right elbow |
| Jonathan Herrera | 3B-2B | 30.153 | Chicago Cubs | Chicago Cubs (MLB) | Contract purchased from minors |
| Dallas Beeler | P | 25.297 | Chicago Cubs | Chicago Cubs (MLB) | DL-15 Right shoulder inflammation |
| Craig Kimbrel | RP | 26.312 | San Diego Padres | San Diego Padres (MLB) | Traded from Braves with Melvin Upton Jr to Padres for Cameron Maybin, Carlos Quentin, Matt Wisler, Jordan Paroubeck and 41st overall pick in 2015 draft |
| Melvin Upton | cf | 30.227 | San Diego Padres | San Diego Padres (MLB) | Traded from Braves with Craig Kimrbel to Padres for Cameron Maybin, Carlos Quentin, Matt Wisler, Jordan Paroubeck and 41st overall pick in 2015 draft |
| Cameron Maybin | CF | 28.001 | Atlanta Braves | Atlanta Braves (MLB) | Traded from Padres with Carlos Quentin, Matt Wisler, Jordan Paroubeck and 41st pick in 2015 draft to Braves for Craig Kimbrel and Melvin Upton Jr. |
| Carlos Quentin | lf | 32.220 | Atlanta Braves | Atlanta Braves (MLB) | Traded from Padres with Cameron Maybin, Matt Wisler, Jordan Paroubeck and 41st pick in 2015 draft to Braves for Craig Kimbrel and Melvin Upton Jr. |
| Matt Wisler | P | 22.205 | Atlanta Braves | Atlanta Braves (MLB) | Traded from Padres with Cameron Maybin, Carlos Quentin, Jordan Paroubeck and 41st pick in 2015 draft to Braves for Craig Kimbrel and Melvin Upton Jr. |
| Jordan Paroubeck | CF | 20.154 | Atlanta Braves | Atlanta Braves (MLB) | Traded from Padres with Carlos Quentin, Matt Wisler, Cameron Maybin and 41st pick in 2015 draft to Braves for Craig Kimbrel and Melvin Upton Jr. |
| Drew Smyly | RP | 25.296 | Tampa Bay Rays | Tampa Bay Rays (MLB) | DL-15 Left shoulder tendinitis |
| Fernando Baez | | 23.064 | St. Louis Cardinals | Peoria (A) | Assigned to Peoria (A) |
| Derek Campbell | IF | 23.282 | Philadelphia Phillies | Lakewood (A) | Assigned to Lakewood (A) |
| Robbie Ray | P | 23.187 | Arizona Diamondbacks | Reno (AAA) | Assigned to Reno (AAA) |
| Blake Hassebrock | P | 25.264 | Oakland Athletics | Midland (AA) | Assigned to Midland (AA) |
