| Aaron Thompson | P | 27.184 | Minnesota Twins | Minnesota Twins (MLB) | Contract purchased from minors |
| Wei-Yin Chen | SP | 29.041 | Baltimore Orioles | Baltimore Orioles (MLB) | Recalled from Gulf Coast Orioles (Rk) |
| Grant Green | 2b | 26.339 | Los Angeles Angels | Los Angeles Angels (MLB) | Activated from DL |
| Moises Sierra | rf | 25.341 | Chicago White Sox | Chicago White Sox (MLB) | Recalled from minor league rehab assignment |
| Moises Sierra | rf | 25.341 | Chicago White Sox | Chicago White Sox (MLB) | Activated from DL |
| Scott Snodgress | P | 24.345 | Chicago White Sox | Chicago White Sox (MLB) | Contract purchased from minors |
| Andy Wilkins | 1B | 25.352 | Chicago White Sox | Chicago White Sox (MLB) | Contract purchased from minors |
| Jason Marquis | SP | 36.010 | - | | Released by Phillies |
| Pete Kozma | 2B | 26.142 | St. Louis Cardinals | St. Louis Cardinals (MLB) | Recalled from Memphis (AAA) |
| Kevin Siegrist | RP | 25.042 | St. Louis Cardinals | St. Louis Cardinals (MLB) | Recalled from Memphis (AAA) |
| Hyun-Jin Ryu | SP | 27.159 | Los Angeles Dodgers | Los Angeles Dodgers (MLB) | Activated from DL |
| Juan Uribe | 3b | 35.162 | Los Angeles Dodgers | Los Angeles Dodgers (MLB) | Activated from DL |
| Nolan Sanburn | OF | 23.041 | Chicago White Sox | Chicago White Sox (MLB) | Traded from Athletics to White Sox for Adam Dunn |
| Zach McAllister | RP | 26.267 | Cleveland Indians | Cleveland Indians (MLB) | Recalled from Columbus (AAA) |
| Josh Tomlin | P | 29.316 | Cleveland Indians | Cleveland Indians (MLB) | Placed on Paternity Leave list |
| Justin Miller | P | 27.079 | Detroit Tigers | Detroit Tigers (MLB) | Outrighted to minors |
| Jose Ortega | RP | 25.323 | Detroit Tigers | Detroit Tigers (MLB) | Outrighted to minors |
| Terrance Gore | CF | 23.084 | Kansas City Royals | Kansas City Royals (MLB) | Contract purchased from minors |
| Sergio Santos | RP | 31.058 | Toronto Blue Jays | Toronto Blue Jays (MLB) | Outrighted to minors |
| Hector Sanchez | c | 24.287 | San Francisco Giants | San Francisco Giants (MLB) | Transferred to 60-day DL |
| Ali Solis | C | 26.337 | Tampa Bay Rays | Tampa Bay Rays (MLB) | Recalled from Durham (AAA) |
| Ali Solis | C | 26.337 | Tampa Bay Rays | Tampa Bay Rays (MLB) | Outrighted to minors |
| Jonathan Broxton | RP | 30.076 | Milwaukee Brewers | Milwaukee Brewers (MLB) | Traded from Reds to Brewers for 2 Players to be Named Later |
| Adam Dunn | dh | 34.296 | Oakland Athletics | Oakland Athletics (MLB) | Traded from White Sox to Athletics for Nolan Sanburn |
| Tim Atherton | P | 24.297 | Oakland Athletics | Sacramento (AAA) | Activated from disabled list |
| Travis Ballew | P | 23.122 | Houston Astros | Corpus Christi (AA) | Reinstated to active roster |
| Christopher Beck | P | 23.361 | Chicago White Sox | Charlotte (AAA) | Activated from disabled list |
| Jose Berrios | P | 20.096 | Minnesota Twins | Rochester (AAA) | Assigned to Rochester (AAA) |
| Dan Burawa | P | 25.244 | New York Yankees | Scranton/Wilkes-Barre (AAA) | Assigned to Scranton/Wilkes-Barre (AAA) |
| Andrew Carraway | P | 27.361 | Seattle Mariners | Tacoma (AAA) | Reinstated to active roster |
| Lendy Castillo | RP | 25.145 | Chicago Cubs | Tennessee (AA) | Activated from disabled list |
| Steve Clevenger | 3b | 28.148 | Baltimore Orioles | Aberdeen (A-) | Assigned to Aberdeen (A-) |
| Jordan Cooper | P | 25.113 | Cleveland Indians | Akron (AA) | Assigned to Akron (AA) |
| Jonathan Cornelius | P | 26.092 | St. Louis Cardinals | Springfield (AA) | Assigned to Springfield (AA) |
| Kevin Cornelius | SS | 22.003 | New York Yankees | Charleston (sc) (A) | Assigned to Charleston (Sc) (A) |
| Cale Coshow | P | 22.046 | New York Yankees | Charleston (sc) (A) | Assigned to Charleston (Sc) (A) |
| Ivan DeJesus | 2B | 27.122 | Boston Red Sox | Pawtucket (AAA) | Assigned to Pawtucket (AAA) |
| Jose Dominguez | RP | 24.024 | Los Angeles Dodgers | Ogden (Rk) | Assigned to Ogden (Rk) for rehab |
| Paolo Espino | P | 27.233 | Washington Nationals | Syracuse (AAA) | Assigned to Syracuse (AAA) |
| Ramon Flores | LF | 22.158 | New York Yankees | Scranton/Wilkes-Barre (AAA) | Assigned to Scranton/Wilkes-Barre (AAA) |
| Greg Garcia | 2B | 25.023 | St. Louis Cardinals | Memphis (AAA) | Assigned to Memphis (AAA) |
| Onelki Garcia | P | 25.029 | Los Angeles Dodgers | Rancho Cucamonga (A+) | Assigned to Rancho Cucamonga (A+) for rehab |
| Marten Gasparini | SS | 17.099 | Kansas City Royals | Idaho Falls (Rk) | Activated from disabled list |
| Marco Gonzales | P | 22.197 | St. Louis Cardinals | Springfield (AA) | Assigned to Springfield (AA) |
| Jose Gonzalez | C | 27.069 | Colorado Rockies | Colorado Springs (AAA) | Reinstated to active roster |
| Nick Greenwood | P | 26.338 | St. Louis Cardinals | Springfield (AA) | Assigned to Springfield (AA) |
| Tayron Guerrero | P | 23.234 | San Diego Padres | Lake Elsinore (A+) | Activated from disabled list |
| Tyler Hanover | IF | 25.006 | Detroit Tigers | Erie (AA) | Assigned to Erie (AA) |
| Mitch Harris | P | 28.297 | St. Louis Cardinals | Memphis (AAA) | Assigned to Memphis (AAA) |
| Blake Hassebrock | P | 25.047 | Oakland Athletics | Sacramento (AAA) | Assigned to Sacramento (AAA) |
| Ralph Henriquez | C | 27.146 | Pittsburgh Pirates | Altoona (AA) | Activated from disabled list |
| Mike Hessman | 1B | 36.179 | Detroit Tigers | Toledo (AAA) | Reinstated to active roster |
| Stewart Ijames | OF | 26.010 | Arizona Diamondbacks | Hillsboro (A-) | Assigned to Hillsboro (A-) |
| Michael Joseph | P | 23.353 | Baltimore Orioles | Delmarva (A) | Assigned to Delmarva (A) |
| Josh Lindblom | SP | 27.077 | Oakland Athletics | Sacramento (AAA) | Activated from disabled list |
| Elvin Liriano | P | 21.318 | San Diego Padres | Eugene (A-) | Assigned to Eugene (A-) |
| Tyler Lyons | SP | 26.192 | St. Louis Cardinals | Springfield (AA) | Assigned to Springfield (AA) |
| Joseph Maher | P | 22.026 | New York Yankees | Charleston (sc) (A) | Assigned to Charleston (Sc) (A) |
| Josh Martin | P | 24.244 | Cleveland Indians | Akron (AA) | Assigned to Akron (AA) |
| Marcos Mateo | P | 30.135 | Chicago Cubs | Iowa (AAA) | Activated from disabled list |
| Kevin Matthews | P | 21.275 | Texas Rangers | Hickory (A) | Assigned to Hickory (A) |
| Mike Mayers | P | 22.269 | St. Louis Cardinals | Memphis (AAA) | Assigned to Memphis (AAA) |
| Brenden McCurry | P | 22.237 | Oakland Athletics | Stockton (A+) | Assigned to Stockton (A+) |
| Trevor Mitsui | 1B | 21.334 | Arizona Diamondbacks | South Bend (A) | Assigned to South Bend (A) |
| Ryan O'Rourke | P | 26.123 | Minnesota Twins | Rochester (AAA) | Assigned to Rochester (AAA) |
| Cord Phelps | 2b | 27.220 | Baltimore Orioles | Norfolk (AAA) | Assigned to Norfolk (AAA) |
| Jordan Piche' | P | 22.363 | Los Angeles Angels | Arizona Angels (Rk) | Activated from disabled list |
| Joel Polanco | C | 28.338 | Baltimore Orioles | Bowie (AA) | Assigned to Bowie (AA) |
| Erasmo Ramirez | SP | 24.121 | Seattle Mariners | Tacoma (AAA) | Assigned to Tacoma (AAA) |
| Anthony Ranaudo | P | 24.356 | Boston Red Sox | Greenville (A) | Assigned to Greenville (A) |
| Zac Rosscup | P | 26.083 | Chicago Cubs | Iowa (AAA) | Assigned to Iowa (AAA) |
| Kyle Ryan | P | 22.341 | Detroit Tigers | Toledo (AAA) | Assigned to Toledo (AAA) |
| Chris Sadberry | P | 22.297 | Miami Marlins | Greensboro (A) | Activated from disabled list |
| Jake Sanchez | P | 25.012 | Oakland Athletics | Stockton (A+) | Activated from disabled list |
| Jonathan Schwind | C | 24.093 | Pittsburgh Pirates | Bradenton (A+) | Assigned to Bradenton (A+) |
| Ross Seaton | P | 24.347 | Houston Astros | Oklahoma City (AAA) | Reinstated to active roster |
| Mark Serrano | P | 28.351 | Arizona Diamondbacks | Reno (AAA) | Activated from disabled list |
| Grant Sides | P | 25.070 | Cleveland Indians | Akron (AA) | Assigned to Akron (AA) |
| DJ Snelten | P | 22.094 | San Francisco Giants | Augusta (A) | Assigned to Augusta (A) |
| Ali Solis | C | 26.337 | Tampa Bay Rays | Durham (AAA) | Assigned to Durham (AAA) |
| Bryce Stowell | P | 27.342 | Tampa Bay Rays | Durham (AAA) | Assigned to Durham (AAA) |
| Eric Surkamp | SP | 27.046 | Chicago White Sox | Charlotte (AAA) | Assigned to Charlotte (AAA) |
| Sam Tuivailala | 3B | 21.316 | St. Louis Cardinals | Memphis (AAA) | Assigned to Memphis (AAA) |
| Ben White | P | 25.113 | Toronto Blue Jays | New Hampshire (AA) | Assigned to New Hampshire (AA) |
| Gustavo Pierre | SS | 22.247 | Philadelphia Phillies | Philadelphia Phillies (MLB) | Traded from Blue Jays to Phillies for John Mayberry Jr. |
| Brayan Villarreal | RP | 27.113 | Boston Red Sox | Pawtucket (AAA) | DL-7 Injured |
| Joshua Stinson | RP | 26.170 | Baltimore Orioles | Gulf Coast Orioles (Rk) | Assigned to GCL Orioles (Rk) |
| Jhonatan Ramos | P | 25.024 | Pittsburgh Pirates | Altoona (AA) | DL-7 Injured |
| Merrill Kelly | P | 25.321 | Tampa Bay Rays | Durham (AAA) | Placed on temporary inactive list |
| Sugar Ray Marimon | P | 25.335 | Kansas City Royals | Northwest Arkansas (AA) | Placed on temporary inactive list |
| Alen Hanson | SS | 21.313 | Pittsburgh Pirates | Altoona (AA) | DL-7 Injured |
| Cody Fassold | P | 25.333 | Atlanta Braves | Lynchburg (A+) | DL-7 Injured |
| Tim Melville | P | 24.326 | Kansas City Royals | Northwest Arkansas (AA) | Placed on temporary inactive list |
| Travis Jankowski | OF | 23.077 | San Diego Padres | San Antonio (AA) | DL-7 Injured |
| Ben Brewster | P | 22.291 | Chicago White Sox | Winston-Salem (A+) | DL-7 Injured |
| Chaz Hebert | P | 21.361 | New York Yankees | Gulf Coast Yankees (Rk) | Assigned to GCL Yankees (Rk) |
| Pedro Perez | C | 23.115 | Baltimore Orioles | Gulf Coast Orioles (Rk) | Assigned to GCL Orioles (Rk) |
| Robbie Garvey | CF-LF | 25.127 | Los Angeles Dodgers | Rancho Cucamonga (A+) | DL-7 Injured |
| Adam Landecker | IF | 23.211 | Pittsburgh Pirates | West Virginia (A) | DL-7 Injured |
| Artie Lewicki | P | 22.145 | Detroit Tigers | West Michigan (A) | DL-7 Injured |
| Chih Fang Pan | 2B | 23.292 | Oakland Athletics | Beloit (A) | DL-7 Injured |
| Jonathan Martinez | P | 20.065 | Chicago Cubs | Kane County (A) | Placed on temporary inactive list |
| Junior Mendez | P | 21.345 | Oakland Athletics | Beloit (A) | DL-7 Injured |
| Richard Stock | C | 23.204 | Cleveland Indians | Lake County (A) | DL-7 Injured |
| Tyler Vail | P | 22.302 | Oakland Athletics | Beloit (A) | DL-7 Injured |
| Austin Pfeiffer | SS | 23.098 | Baltimore Orioles | Gulf Coast Orioles (Rk) | Assigned to GCL Orioles (Rk) |
| Sean Brady | P | 20.083 | Cleveland Indians | Mahoning Valley (A-) | Placed on temporary inactive list |
| John Mayberry | rf-cf | 30.254 | Toronto Blue Jays | Toronto Blue Jays (MLB) | Traded from Phillies to Blue Jays for Gustavo Pierre |
| John Holdzkom | P | 26.317 | Pittsburgh Pirates | Pittsburgh Pirates (MLB) | Contract purchased from minors |
| Rich Hill | RP | 34.173 | New York Yankees | New York Yankees (MLB) | Outrighted to minors |
| Neil Wagner | RP | 30.243 | Toronto Blue Jays | Toronto Blue Jays (MLB) | Designated for Assignment |
| Andy Dirks | lf | 28.219 | Detroit Tigers | Detroit Tigers (MLB) | Recalled from minor league rehab assignment |
| Phillip Irwin | P | 27.187 | - | | Cleared Waivers and Became a Free Agent |
| John Mayberry | rf-cf | 30.254 | Toronto Blue Jays | Toronto Blue Jays (MLB) | Activated from DL |
| Edgar Ibarra | P | 25.092 | Minnesota Twins | New Britain (AA) | Outrighted to minors |
