| Nick Buss | CF | 27.202 | Oakland Athletics | Oakland Athletics (MLB) | Designated for Assignment |
| Dan Straily | SP | 25.216 | Oakland Athletics | Oakland Athletics (MLB) | Recalled from Sacramento (AAA) |
| Eury De La Rosa | RP | 24.131 | Arizona Diamondbacks | Arizona Diamondbacks (MLB) | Recalled from Reno (AAA) |
| Kameron Loe | RP | 32.298 | Arizona Diamondbacks | Arizona Diamondbacks (MLB) | Signed to minor league contract |
| Tom Layne | RP | 29.245 | Boston Red Sox | Boston Red Sox (MLB) | Contract purchased from minors |
| Chris Rusin | SP | 27.256 | Chicago Cubs | Chicago Cubs (MLB) | Recalled from Iowa (AAA) |
| Boone Logan | RP | 29.326 | Colorado Rockies | Colorado Rockies (MLB) | Recalled from minor league rehab assignment |
| Preston Guilmet | RP | 26.344 | Baltimore Orioles | Baltimore Orioles (MLB) | Recalled from Norfolk (AAA) |
| Rich Hill | RP | 34.116 | Los Angeles Angels | Los Angeles Angels (MLB) | Designated for Assignment |
| Michael Roth | RP | 24.140 | Los Angeles Angels | Los Angeles Angels (MLB) | Contract purchased from minors |
| Boone Logan | RP | 29.326 | Colorado Rockies | Colorado Rockies (MLB) | Activated from DL |
| Tony Campana | cf | 28.036 | Los Angeles Angels | Los Angeles Angels (MLB) | Traded from Diamondbacks with Joe Thatcher to Angels for Zach Borenstein and Joey Krehbiel |
| Joe Thatcher | RP | 33.086 | Los Angeles Angels | Los Angeles Angels (MLB) | Traded From Arizona (with OF Tony Campana, four-player deal) |
| Jeff Samardzija | SP | 29.163 | Oakland Athletics | Oakland Athletics (MLB) | Traded from Cubs with Jason Hammel to Athletics for Addison Rusell, Billy McKinney, Dan Straily and PTBNL |
| Dan Straily | SP | 25.216 | Chicago Cubs | Chicago Cubs (MLB) | Traded from Athletics with Billy McKinney, Addison Russell and PTBNL to Cubs for Jeff Samardzija and Jason Hammel |
| Cole Gillespie | rf | 30.015 | Toronto Blue Jays | Toronto Blue Jays (MLB) | Claimed off waivers from Mariners by Blue Jays |
| Mike Gonzalez | RP | 36.043 | - | | Released by Nationals |
| Dean Anna | 2B | 27.223 | Pittsburgh Pirates | Pittsburgh Pirates (MLB) | Claimed off waivers from Yankees by Pirates |
| Zach Borenstein | LF | 23.347 | Arizona Diamondbacks | Arizona Diamondbacks (MLB) | Traded from Angels with Joey Krehbiel to Diamondbacks for Joe Thatcher and Tony Campana |
| Ryan Adams | 2B | 27.075 | Los Angeles Dodgers | Arizona Dodgers (Rk) | Activated from disabled list |
| Ehire Adrianza | SS | 24.318 | San Francisco Giants | Fresno (AAA) | Assigned to Fresno (AAA) for rehab |
| Yency Almonte | P | 20.031 | Los Angeles Angels | Burlington (A) | Assigned to Burlington (A) |
| Elvis Araujo | P | 22.356 | Cleveland Indians | Akron (AA) | Assigned to Akron (AA) |
| Francisco Arcia | C | 24.294 | New York Yankees | Trenton (AA) | Assigned to Trenton (AA) |
| Tim Atherton | P | 24.240 | Oakland Athletics | Sacramento (AAA) | Assigned to Sacramento (AAA) |
| Jason Berken | P | 30.221 | San Francisco Giants | Fresno (AAA) | Activated from disabled list |
| Carson Blair | C | 24.260 | Boston Red Sox | Salem (A+) | Activated from disabled list |
| Zach Borenstein | LF | 23.347 | Arizona Diamondbacks | Mobile (AA) | Assigned to Mobile (AA) |
| Matt Boyd | P | 23.153 | Toronto Blue Jays | New Hampshire (AA) | Assigned to New Hampshire (AA) |
| Tony Campana | cf | 28.036 | Los Angeles Angels | Salt Lake (AAA) | Assigned to Salt Lake (AAA) |
| Matt Carson | LF | 33.004 | Cleveland Indians | Columbus (AAA) | Activated from disabled list |
| Matt Clark | LF-1B | 27.207 | Milwaukee Brewers | Nashville (AAA) | Signed to Minor League Contract |
| Delta Cleary | CF | 24.325 | Colorado Rockies | Tulsa (AA) | Assigned to Tulsa (AA) |
| Dylan Covey | P | 22.326 | Oakland Athletics | Beloit (A) | Activated from disabled list |
| Claudio Custodio | SS | 23.248 | New York Yankees | Tampa (A+) | Activated from disabled list |
| Chris Devenski | P | 23.234 | Houston Astros | Corpus Christi (AA) | Assigned to Corpus Christi (AA) |
| Tim Fedroff | CF-LF | 27.151 | Cleveland Indians | Akron (AA) | Assigned to Akron (AA) |
| Seth Frankoff | P | 25.312 | Oakland Athletics | Sacramento (AAA) | Assigned to Sacramento (AAA) |
| Tyler Gagnon | P | 25.105 | Colorado Rockies | Modesto (A+) | Assigned to Modesto (A+) |
| Mitch Garver | C | 23.171 | Minnesota Twins | Cedar Rapids (A) | Activated from disabled list |
| Matt Gedman | 3B | 25.282 | Boston Red Sox | Salem (A+) | Activated from disabled list |
| Erik Gonzalez | 3B | 22.309 | Cleveland Indians | Carolina (A+) | Assigned to Carolina (A+) |
| Anthony Gose | cf | 23.329 | Toronto Blue Jays | Buffalo (AAA) | Assigned to Buffalo (AAA) |
| Cameron Griffin | P | 23.010 | New York Mets | Brooklyn (A-) | Assigned to Brooklyn (A-) |
| Taylor Guerrieri | P | 21.216 | Tampa Bay Rays | Bowling Green (A) | Assigned to Bowling Green (A) |
| Steve Johnson | RP | 26.309 | Baltimore Orioles | Gulf Coast Orioles (Rk) | Assigned to GCL Orioles (Rk) for rehab |
| Micah Kellogg | P | 24.218 | Detroit Tigers | Gulf Coast Tigers (East) (Rk) | Assigned to Gulf Coast Tigers (Rk) |
| Joey Krehbiel | P | 21.197 | Arizona Diamondbacks | Visalia (A+) | Assigned to Visalia (A+) |
| John Lannan | SP | 29.281 | New York Mets | St. Lucie (A+) | Assigned to St. Lucie (A+) |
| Kameron Loe | RP | 32.298 | Arizona Diamondbacks | Reno (AAA) | Assigned to Reno (AAA) |
| Matt Long | CF-RF | 27.066 | Los Angeles Angels | Arkansas (AA) | Assigned to Arkansas (AA) |
| Jeff Manship | SP | 29.170 | Philadelphia Phillies | Gulf Coast Phillies (Rk) | Assigned to GCL Phillies (Rk) for rehab |
| Dustin Martin | RF | 30.092 | Arizona Diamondbacks | Reno (AAA) | Assigned to Reno (AAA) |
| Craig Massoni | 1B | 22.250 | San Francisco Giants | Augusta (A) | Assigned to Augusta (A) |
| Marcos Mateo | P | 30.078 | Chicago Cubs | Iowa (AAA) | Activated from disabled list |
| Lucas May | C | 29.254 | Milwaukee Brewers | Nashville (AAA) | Assigned to Nashville (AAA) |
| Jake Mayers | P-3B | 23.331 | Arizona Diamondbacks | Hillsboro (A-) | Assigned to Hillsboro (A-) |
| Melvin Mercedes | SS | 22.174 | Oakland Athletics | Beloit (A) | Activated from disabled list |
| Tommy Milone | SP | 27.139 | Oakland Athletics | Sacramento (AAA) | Assigned to Sacramento (AAA) |
| Raymundo Montero | P | 24.288 | San Francisco Giants | Augusta (A) | Assigned to Augusta (A) |
| Josh Mueller | P | 25.168 | Colorado Rockies | Modesto (A+) | Assigned to Modesto (A+) |
| Wil Nieves | c | 36.283 | Philadelphia Phillies | Gulf Coast Phillies (Rk) | Assigned to GCL Phillies (Rk) for rehab |
| Brett Oberholtzer | SP | 25.004 | Houston Astros | Oklahoma City (AAA) | Assigned to Oklahoma City (AAA) |
| Jeremias Pineda | CF | 23.231 | Minnesota Twins | Cedar Rapids (A) | Assigned to Cedar Rapids (A) |
| Edwin Quirarte | P | 27.197 | San Francisco Giants | Richmond (AA) | Activated from disabled list |
| Lance Ray | RF-1B | 24.306 | Minnesota Twins | New Britain (AA) | Assigned to New Britain (AA) |
| Genison Reyes | P | 22.290 | San Diego Padres | Lake Elsinore (A+) | Assigned to Lake Elsinore (A+) |
| Harold Riggins | 1B | 24.121 | Cincinnati Reds | Bakersfield (A+) | Assigned to Bakersfield (A+) |
| Andrew Robinson | P | 26.143 | Atlanta Braves | Mississippi (AA) | Traded from Astros to Braves for PTBNL (Jared Cruz) |
| Patrick Schuster | P | 23.248 | Arizona Diamondbacks | Reno (AAA) | Assigned to Reno (AAA) |
| Alfredo Silverio | CF-LF | 27.060 | Miami Marlins | New Orleans (AAA) | Assigned to New Orleans (AAA) |
| Geovany Soto | c | 31.166 | Texas Rangers | Round Rock (AAA) | Assigned to Round Rock (AAA) for rehab |
| Elias Torres | | 22.134 | Tampa Bay Rays | Bowling Green (A) | Assigned to Bowling Green (A) |
| Orvin Tovar | | 20.333 | Detroit Tigers | Gulf Coast Tigers (East) (Rk) | Assigned to Gulf Coast Tigers (Rk) |
| Blake Treinen | P | 26.005 | Washington Nationals | Syracuse (AAA) | Assigned to Syracuse (AAA) |
| Stephen Tromblee | P | 25.093 | Los Angeles Angels | Arizona Angels (Rk) | Activated from disabled list |
| Henry Urrutia | dh | 27.142 | Baltimore Orioles | Gulf Coast Orioles (Rk) | Activated from disabled list |
| Logan Wade | 2B | 22.235 | Minnesota Twins | Cedar Rapids (A) | Assigned to Cedar Rapids (A) |
| Colin Walsh | 3B-LF | 24.282 | Oakland Athletics | Sacramento (AAA) | Assigned to Sacramento (AAA) |
| Adam Weisenburger | C | 25.204 | Milwaukee Brewers | Huntsville (AA) | Activated from disabled list |
| Robert Whalen | P | 20.155 | New York Mets | Gulf Coast Mets (Rk) | Activated from disabled list |
| Cody Wheeler | OF-P | 24.320 | Arizona Diamondbacks | Mobile (AA) | Assigned to Mobile (AA) |
| Ryan Wheeler | 1b | 25.360 | Colorado Rockies | Colorado Springs (AAA) | Assigned to Colorado Springs (AAA) |
| Luis Ayala | RP | 36.174 | | | Released by Blue Jays |
| Jake Brigham | P | 26.146 | Pittsburgh Pirates | Indianapolis (AAA) | DL-7 Injured |
| Jimmy Swift | 1B-LF | 26.197 | | | Released by Angels |
| Chad Pinder | IF | 22.098 | Oakland Athletics | Stockton (A+) | DL-7 Injured |
| Jose Rosario | SS-2B | 22.219 | New York Yankees | Tampa (A+) | DL-7 Injured |
| Drew Steckenrider | OF-P | 23.176 | Miami Marlins | Gulf Coast Marlins (Rk) | DL-7 Injured |
| Nick Urbanus | SS-2B | 22.098 | Texas Rangers | Arizona Rangers (Rk) | DL-7 Injured |
| Tony Wieber | P | 23.145 | | | Released by Padres |
| Damian Defrank | p | 19.154 | Minnesota Twins | Gulf Coast Twins (Rk) | DL-7 Injured |
| Jake Pintar | P | 20.142 | | | Released by Orioles |
| Leonel Zazueta | p | 19.281 | Minnesota Twins | Gulf Coast Twins (Rk) | DL-7 Injured |
| Sean McAdams | P | 20.230 | | | Released by Orioles |
| Taylor Harbin | SS | 28.142 | | | Released by Marlins |
| Manny Machado | 3b | 21.364 | Baltimore Orioles | Baltimore Orioles (MLB) | Reinstated from suspension |
| Scott Downs | RP | 38.110 | - | | Cleared Waivers and Became a Free Agent |
| Kenny Wilson | CF | 24.156 | Toronto Blue Jays | Toronto Blue Jays (MLB) | Designated for Assignment |
| Mike Snyder | 3B | 24.018 | Los Angeles Angels | Arkansas (AA) | Assigned to Arkansas (AA) |
| Dario Beltre | P | 21.228 | Texas Rangers | Spokane (A-) | Assigned to Spokane (A-) |
| Jon Wandling | P | 22.038 | Toronto Blue Jays | Dunedin (A+) | Assigned to Dunedin (A+) |
| Kevin Alexander | P | 23.062 | St. Louis Cardinals | Palm Beach (A+) | Assigned to Palm Beach (A+) |
| Braxton Lee | OF | 20.316 | Tampa Bay Rays | Hudson Valley (A-) | Signed out of draft (Mississippi) |
| Danny Wissmann | P | 22.060 | San Diego Padres | Eugene (A-) | Signed out of draft (SC-Aiken) |
| Sean Carley | P | 23.189 | New York Yankees | Staten Island (A-) | Assigned to Staten Island (A-) |
| Bryan Dobzanski | P | 18.309 | St. Louis Cardinals | Gulf Coast Cardinals (Rk) | Signed out of draft (New Jersey HS) |
| Cole Brocker | P | 24.079 | Atlanta Braves | Gulf Coast Braves (Rk) | Signed out of draft (Oregon State) |
| Grant Hockin | P | 18.122 | Cleveland Indians | Arizona Indians (Rk) | Signed out of draft (California HS) |
| James Connell | P | 23.167 | | | Released by Angels |
| Joe Filomeno | P | 21.186 | Texas Rangers | Arizona Rangers (Rk) | Signed out of draft (Louisville) |
| Travis Banwart | P | 28.141 | | | Released by Indians |
