| Mickey Storey | RP | 27.153 | Toronto Blue Jays | Buffalo (AAA) | Optioned to Buffalo (AAA) |
| Adron Chambers | rf | 26.312 | St. Louis Cardinals | Memphis (AAA) | Optioned to Memphis (AAA) |
| Kolten Wong | 2b | 22.310 | St. Louis Cardinals | St. Louis Cardinals (MLB) | Contract purchased from Memphis (AAA) |
| Jose Alvarez | RP-SP | 24.102 | Detroit Tigers | Detroit Tigers (MLB) | Recalled from Toledo (AAA) |
| Danny Duffy | SP | 24.238 | Kansas City Royals | Kansas City Royals (MLB) | Recalled from Omaha (AAA) |
| Anthony Gose | cf | 23.006 | Toronto Blue Jays | Toronto Blue Jays (MLB) | Recalled from Buffalo (AAA) |
| Mike Wilson | OF | 30.048 | San Diego Padres | Tucson (AAA) | DL-7 Injured |
| Aaron Hicks | cf | 23.318 | Minnesota Twins | Rochester (AAA) | DL-7 Injured |
| Brad Davis | C | 30.230 | | | Announced retirement |
| Kelson Brown | 2B | 25.283 | Pittsburgh Pirates | Altoona (AA) | DL-7 Injured |
| Hector Nelo | P | 26.284 | Los Angeles Dodgers | Chattanooga (AA) | DL-7 Injured |
| Jake Lemmerman | SS | 24.104 | St. Louis Cardinals | Springfield (AA) | DL-7 Injured |
| Josh Mueller | P | 24.210 | Colorado Rockies | Tulsa (AA) | DL-7 Injured |
| Michael Solbach | P | 28.016 | Colorado Rockies | Tulsa (AA) | Activated from temporarily inactive list |
| Roman Hernandez | LF | 25.220 | Kansas City Royals | Northwest Arkansas (AA) | DL-7 Injured |
| Nathan Melendres | CF-LF | 23.134 | Seattle Mariners | High Desert (A+) | DL-7 Injured |
| Matt Duffy | IF | 22.213 | San Francisco Giants | San Jose (A+) | DL-7 Injured |
| Byron Capellan | SS | 20.007 | Baltimore Orioles | Frederick (A+) | DL-7 Injured |
| Matthew Shepherd | SS | 23.106 | San Diego Padres | Fort Wayne (A) | DL-7 Injured |
| James Baldwin | CF | 21.311 | Los Angeles Dodgers | Great Lakes (A) | DL-7 Injured |
| Ramon Del Orbe | P | 21.181 | Miami Marlins | Greensboro (A) | DL-7 Skull fracture |
| Jeffrey Gibbs | P | 22.115 | | | Released by Pirates |
| Moises Hernandez | P | 29.151 | Seattle Mariners | Jackson (AA) | Activated from DL |
| Ryan Bradley | P | 25.032 | San Francisco Giants | Richmond (AA) | Activated from DL |
| Luis Flores | C | 26.287 | Chicago Cubs | Iowa (AAA) | Activated from DL |
| Matt Hoffman | P | 24.271 | Detroit Tigers | Toledo (AAA) | Activated from DL |
| Tyler Deloach | P | 22.126 | Los Angeles Angels | Burlington (A) | Activated from DL |
| Eric Semmelhack | P | 22.221 | Milwaukee Brewers | Wisconsin (A) | Activated from DL |
| Ryan Garvey | OF | 20.139 | Colorado Rockies | Grand Junction (Rk) | DL-7 Injured |
| Trevor Miller | P | 22.064 | Seattle Mariners | Jackson (AA) | Activated from DL |
| Luis Niebla | P | 22.224 | New York Yankees | Charleston (sc) (A) | Activated from DL |
| J.A. Happ | SP | 30.301 | Toronto Blue Jays | Toronto Blue Jays (MLB) | Reinstated from Bereavement List |
| Munenori Kawasaki | 2b | 32.074 | Toronto Blue Jays | Toronto Blue Jays (MLB) | Placed on Paternity Leave list |
| John Lannan | SP | 28.323 | Philadelphia Phillies | Philadelphia Phillies (MLB) | DL-15 Left knee tendinitis |
| B.J. Rosenberg | RP | 27.333 | Philadelphia Phillies | Philadelphia Phillies (MLB) | Recalled from Lehigh Valley (AAA) |
| Brett Hayes | c | 29.185 | Kansas City Royals | Omaha (AAA) | Outrighted to Omaha (AAA) |
| Phil Gosselin | 2b | 24.317 | Atlanta Braves | Atlanta Braves (MLB) | Contract purchased from Gwinnett (AAA) |
| Tyler Pastornicky | 2b | 23.246 | Atlanta Braves | Atlanta Braves (MLB) | DL-15 Torn left ACL [Collision in field with RF Jason Heyward] |
| Jake Arrieta | SP | 27.163 | Chicago Cubs | Chicago Cubs (MLB) | Recalled from Iowa (AAA) |
| Eduardo Sanchez | RP | 24.181 | Chicago Cubs | Iowa (AAA) | Optioned to Iowa (AAA) |
| Alfredo Figaro | RP | 29.040 | Milwaukee Brewers | Nashville (AAA) | Optioned to Nashville (AAA) |
| Sean Halton | 1b | 26.070 | Milwaukee Brewers | Milwaukee Brewers (MLB) | Recalled from Nashville (AAA) |
| Chris Colabello | rf | 29.297 | Minnesota Twins | Rochester (AAA) | Optioned to Rochester (AAA) |
| Ryan Doumit | c-dh | 32.135 | Minnesota Twins | Minnesota Twins (MLB) | Activated from DL |
| Mark Reynolds | 1b | 30.013 | New York Yankees | New York Yankees (MLB) | Signed to 1-year contract for 2013-2013 ($0m) |
| Dee Gordon | ss | 25.116 | Los Angeles Dodgers | Albuquerque (AAA) | Optioned to Albuquerque (AAA) |
| Scott Van Slyke | RF-1B | 27.023 | Los Angeles Dodgers | Los Angeles Dodgers (MLB) | Recalled from Albuquerque (AAA) |
| Arquimedes Caminero | RP | 26.061 | Miami Marlins | Miami Marlins (MLB) | Recalled from Jacksonville (AA) |
| Justin Maxwell | rf | 29.284 | Kansas City Royals | Kansas City Royals (MLB) | Placed on bereavement list |
| Will Smith | RP | 24.037 | Kansas City Royals | Kansas City Royals (MLB) | Recalled from Omaha (AAA) |
| Preston Claiborne | RP | 25.208 | New York Yankees | Scranton/Wilkes-Barre (AAA) | Optioned to Scranton/Wilkes-Barre (AAA) |
| Luis Cruz | 3b | 29.188 | New York Yankees | New York Yankees (MLB) | Activated from DL |
| Luis Cruz | 3b | 29.188 | New York Yankees | New York Yankees (MLB) | Designated for Assignment |
| Cristhian Martinez | RP | 31.163 | Atlanta Braves | Mississippi (AA) | Transferred to 60-day DL |
| Kyle Farnsworth | RP | 37.124 | Pittsburgh Pirates | Pittsburgh Pirates (MLB) | Signed to Minor League Contract |
| Peter Bourjos | cf | 26.138 | Los Angeles Angels | Los Angeles Angels (MLB) | Activated from DL |
| Tommy Field | 2b | 26.175 | Los Angeles Angels | Salt Lake (AAA) | Optioned to Salt Lake (AAA) |
| Angel Pagan | cf | 32.045 | San Francisco Giants | Arizona Giants (Rk) | Assigned to Arizona Giants (Rk) for rehab |
| Chad Noble | C | 25.272 | Chicago Cubs | Tennessee (AA) | Assigned to Tennessee (AA) |
| Vladimir Frias | RF-LF | 26.344 | Boston Red Sox | Salem (A+) | Assigned to Salem (A+) |
| Rocky Gale | C | 25.176 | San Diego Padres | San Antonio (AA) | Assigned to San Antonio (AA) |
| Ben Lasater | 1B | 29.083 | Miami Marlins | Gulf Coast Marlins (Rk) | Assigned to Gulf Coast Marlins (Rk) |
| Guillermo Pimentel | RF | 20.315 | Seattle Mariners | High Desert (A+) | Assigned to High Desert (A+) |
| Ben Gamel | RF | 21.091 | New York Yankees | Trenton (AA) | Assigned to Trenton (AA) |
| Mike Dowd | C | 23.128 | Seattle Mariners | High Desert (A+) | Assigned to High Desert (A+) |
| Cody Grice | LF | 23.209 | New York Yankees | Tampa (A+) | Assigned to Tampa (A+) |
| Dawel Lugo | | 18.246 | Toronto Blue Jays | Vancouver (A-) | Assigned to Vancouver (A-) |
| Dawel Lugo | | 18.246 | Toronto Blue Jays | Bluefield (Rk) | Assigned to Bluefield (Rk) |
| Herlis Rodriguez | | 19.067 | Philadelphia Phillies | Gulf Coast Phillies (Rk) | Assigned to Gulf Coast Phillies (Rk) |
| Franklin Barreto | | 17.171 | Toronto Blue Jays | Bluefield (Rk) | Assigned to Bluefield (Rk) |
| Zach Duke | RP | 30.119 | Cincinnati Reds | Louisville (AAA) | Signed to minor league contract |
| Justin Hess | P | 23.000 | Houston Astros | Gulf Coast Astros (Rk) | Assigned to Gulf Coast Astros (Rk) |
| Ross Ohlendorf | RP | 31.008 | Washington Nationals | Potomac (A+) | Assigned to Potomac (A+) for rehab |
| Cole Devries | P | 28.185 | Minnesota Twins | New Britain (AA) | Assigned to New Britain (AA) |
| Josh Tomlin | P | 28.301 | Cleveland Indians | Akron (AA) | Assigned to Akron (AA) for rehab |
| Shaun Ellis | P | 26.257 | Cincinnati Reds | Bakersfield (A+) | Assigned to Bakersfield (A+) |
| Carmine Giardina | P | 25.178 | Los Angeles Angels | Inland Empire (A+) | Assigned to Inland Empire (A+) |
| Henry Mabee | P | 28.037 | Chicago White Sox | Birmingham (AA) | Assigned to Birmingham (AA) |
| Francisley Bueno | RP | 32.164 | Kansas City Royals | Omaha (AAA) | Outrighted to Omaha (AAA) |
| Tommy Hanson | SP | 26.353 | Los Angeles Angels | Salt Lake (AAA) | Assigned to Salt Lake (AAA) |
| Martin Viramontes | P | 24.035 | Milwaukee Brewers | Arizona Brewers (Rk) | Assigned to Arizona Brewers (Rk) |
| Rob Rasmussen | P | 24.136 | Los Angeles Dodgers | Chattanooga (AA) | Assigned to Chattanooga (AA) |
| Tyler Waldron | P | 24.107 | Pittsburgh Pirates | Altoona (AA) | Assigned to Altoona (AA) |
| Grant Monroe | P | 24.321 | Chicago White Sox | Bristol (Rk) | Assigned to Bristol (Rk) |
| Cody Winiarski | P | 23.354 | Chicago White Sox | Birmingham (AA) | Assigned to Birmingham (AA) |
| Zack Dodson | P | 23.024 | Pittsburgh Pirates | Bradenton (A+) | Assigned to Bradenton (A+) |
| Ben Paullus | P | 23.350 | New York Yankees | Tampa (A+) | Assigned to Tampa (A+) |
| David Martinez | P | 26.012 | Houston Astros | Oklahoma City (AAA) | Assigned to Oklahoma City (AAA) |
| Cam Bedrosian | P | 21.319 | Los Angeles Angels | Inland Empire (A+) | Assigned to Inland Empire (A+) |
| Michael Lorenzen | OF | 21.225 | Cincinnati Reds | Pensacola (AA) | Assigned to Pensacola (AA) |
| Daniel Gibson | P | 21.305 | Arizona Diamondbacks | South Bend (A) | Assigned to South Bend (A) |
| Cody Forsythe | P | 22.333 | Philadelphia Phillies | Gulf Coast Phillies (Rk) | Assigned to Gulf Coast Phillies (Rk) |
| Francisco Taveras | P | 23.085 | Boston Red Sox | Greenville (A) | Assigned to Greenville (A) |
| Jose Rosario | P | 22.352 | Chicago Cubs | Boise (A-) | Assigned to Boise (A-) |
| Matt Alvarez | P | 22.217 | Kansas City Royals | Idaho Falls (Rk) | Signed as undrafted free agent out of college |
| Mike Connolly | IF | 21.290 | San Francisco Giants | Salem-Keizer (A-) | Assigned to Salem-Keizer (A-) |
| Robert Stephenson | P | 20.173 | Cincinnati Reds | Pensacola (AA) | Assigned to Pensacola (AA) |
| Rigoberto Arrebato | P | 27.193 | New York Yankees | Trenton (AA) | Assigned to Trenton (AA) |
| Onelki Garcia | P | 24.014 | Los Angeles Dodgers | Albuquerque (AAA) | Assigned to Albuquerque (AAA) |
| Austin Fairchild | P | 19.144 | Kansas City Royals | Idaho Falls (Rk) | Assigned to Idaho Falls (Rk) |
| J.B. Wendelken | P | 20.145 | Chicago White Sox | Winston-Salem (A+) | Assigned to Winston-Salem (A+) |
| Oderman Rocha | | 20.282 | Pittsburgh Pirates | Gulf Coast Pirates (Rk) | Assigned to Gulf Coast Pirates (Rk) |
| Armando Rivero | | 25.197 | Chicago Cubs | Tennessee (AA) | Assigned to Tennessee (AA) |
| Oswaldo Mieres | | 21.094 | Cincinnati Reds | Billings (Rk) | Assigned to Billings (Rk) |
| Ismael Brito | P | 20.146 | St. Louis Cardinals | Johnson City (Rk) | Assigned to Johnson City (Rk) |
| Richard Paulino | P | 18.141 | Atlanta Braves | Gulf Coast Braves (Rk) | |
| Mike Zagurski | RP | 30.201 | | | Opted out of contract and became Free Agent |
