| John Jaso | c | 29.311 | Oakland Athletics | Oakland Athletics (MLB) | DL-7 Concussion [Foul ball off his mask] |
| Carlos Zambrano | P | 32.055 | | | Released by Phillies |
| Willy Taveras | OF | 31.213 | | | Released by Royals |
| Jim Negrych | 2B | 28.146 | New York Mets | Buffalo (AAA) | DL-7 Injured |
| Eric Smith | P | 24.284 | Arizona Diamondbacks | Mobile (AA) | suspended for 50 games for a violation of the Minor League Drug Prevention and Treatment Program |
| Noel Arguelles | P | 23.195 | Kansas City Royals | Northwest Arkansas (AA) | DL-7 left shoulder |
| Vincent Catricala | 3B | 24.268 | Oakland Athletics | Midland (AA) | Outrighted to Midland (AA) |
| Peter Mooney | SS | 22.341 | Toronto Blue Jays | Dunedin (A+) | DL-7 Injured |
| Austin Bibens-Dirkx | P | 28.088 | Toronto Blue Jays | Dunedin (A+) | Placed on temporary inactive list |
| Dan Cevette | P | 29.281 | Pittsburgh Pirates | Bradenton (A+) | DL-7 Injured |
| Marco Grifantini | P | 27.312 | | | Released by Blue Jays |
| Larry Suarez | P | 23.218 | | | Released by Cubs |
| Jamaine Cotton | P | 22.302 | Houston Astros | Quad Cities (A) | DL-7 Injured |
| Jesus Galindo | CF | 22.337 | San Francisco Giants | Augusta (A) | DL-7 Injured |
| Shayne Houck | OF | 23.058 | San Francisco Giants | Augusta (A) | DL-7 Injured |
| Angelo Gumbs | 2B | 20.286 | New York Yankees | Charleston (sc) (A) | Placed on temporary inactive list |
| Derek Jones | OF | 23.053 | Colorado Rockies | Asheville (A) | Placed on temporary inactive list |
| Stephen Branca | SS | 24.107 | San Francisco Giants | Augusta (A) | DL-7 Injured |
| Wes Schill | 2B-SS | 23.246 | Washington Nationals | Hagerstown (A) | DL-7 Injured |
| Claudio Custodio | SS | 22.269 | New York Yankees | Charleston (sc) (A) | Transferred to 60-day DL |
| Jordan Poole | OF | 21.319 | Washington Nationals | Auburn (A-) | DL-7 Injured |
| Reid Redman | IF | 24.246 | | | Released by Marlins |
| Trevor Cahill | SP | 25.147 | Arizona Diamondbacks | Arizona Diamondbacks (Rk) | Assigned to Arizona Diamondbacks (Rk) for rehab |
| Mason Tobin | P | 26.018 | San Francisco Giants | Fresno (AAA) | Activated from DL |
| Chase D'Arnaud | 2b | 26.186 | Pittsburgh Pirates | Indianapolis (AAA) | Activated from DL |
| Colin Bates | P | 25.138 | Washington Nationals | Potomac (A+) | Activated from DL |
| Corey Williams | P | 23.022 | Minnesota Twins | Fort Myers (A+) | Activated from DL |
| Pedro Severino | C | 20.006 | Washington Nationals | Hagerstown (A) | Activated from DL |
| Terrell Joyce | OF | 21.058 | Houston Astros | Quad Cities (A) | Activated from DL |
| Juan Ciriaco | 2B | 23.020 | Colorado Rockies | Asheville (A) | Activated from DL |
| Franklin Navarro | C | 18.282 | Detroit Tigers | Gulf Coast Tigers (East) (Rk) | Activated from DL |
| Rob Wooten | RP | 28.005 | Milwaukee Brewers | Milwaukee Brewers (MLB) | Contract purchased from Nashville (AAA) |
| Ryan Mattheus | RP | 29.259 | Washington Nationals | Washington Nationals (MLB) | Activated from DL |
| Jenrry Mejia | SP | 23.288 | New York Mets | New York Mets (MLB) | Activated from DL |
| Alfonso Soriano | lf | 37.201 | New York Yankees | New York Yankees (MLB) | Traded from Cubs to Yankees for Corey Black |
| Mike Zunino | c | 22.123 | Seattle Mariners | Seattle Mariners (MLB) | DL-15 Fractured left hamate bone [Foul ball off his left hand] |
| Eduardo Sanchez | RP | 24.160 | Chicago Cubs | Chicago Cubs (MLB) | Contract purchased from Iowa (AAA) |
| Corey Dickerson | lf | 24.065 | Colorado Rockies | Colorado Rockies (MLB) | Recalled from Colorado Springs (AAA) |
| Drew Pomeranz | SP | 24.246 | Colorado Rockies | Colorado Rockies (MLB) | DL-15 Left biceps tendinitis |
| Brendan Harris | 2b | 32.334 | New York Yankees | Scranton/Wilkes-Barre (AAA) | Signed to minor league contract |
| Steve Pearce | rf | 30.104 | Baltimore Orioles | Gulf Coast Orioles (Rk) | Assigned to Gulf Coast Orioles (Rk) for rehab |
| Rylan Sandoval | 2B | 25.351 | New York Mets | St. Lucie (A+) | Assigned to St. Lucie (A+) |
| Joe Benson | CF | 25.143 | Texas Rangers | Frisco (AA) | Assigned to Frisco (AA) |
| Lance Zawadzki | IF | 28.061 | Toronto Blue Jays | Gulf Coast Blue Jays (Rk) | Assigned to Gulf Coast Blue Jays (Rk) |
| Jonathan Roof | LF-2B | 24.184 | Philadelphia Phillies | Clearwater (A+) | Assigned to Clearwater (A+) |
| Isaac Galloway | CF | 23.289 | Miami Marlins | Jacksonville (AA) | Assigned to Jacksonville (AA) |
| Yowill Espinal | 2B | 22.116 | Kansas City Royals | Wilmington (A+) | Assigned to Wilmington (A+) |
| Sean Coyle | 2B | 21.191 | Boston Red Sox | Gulf Coast Red Sox (Rk) | Assigned to Gulf Coast Red Sox (Rk) |
| Seth Conner | 3B | 21.179 | Toronto Blue Jays | Vancouver (A-) | Assigned to Vancouver (A-) |
| Jacob Hannemann | CF | 22.088 | Chicago Cubs | Arizona Cubs (Rk) | Assigned to Arizona Cubs (Rk) |
| David Freitas | C | 24.130 | Oakland Athletics | Sacramento (AAA) | Assigned to Sacramento (AAA) |
| Brock Hebert | IF | 22.076 | Seattle Mariners | Everett (A-) | Assigned to Everett (A-) |
| Jack Mayfield | 2b | 22.299 | Houston Astros | Tri City (A-) | Assigned to Tri City (A-) |
| Shawn Payne | CF-LF | 24.019 | San Francisco Giants | Augusta (A) | Assigned to Augusta (A) |
| Jonathan Schoop | 2B | 21.294 | Baltimore Orioles | Norfolk (AAA) | Assigned to Norfolk (AAA) |
| Dan Klein | C | 22.331 | Toronto Blue Jays | Lansing (A) | Assigned to Lansing (A) |
| Ryon Healy | P-IF | 21.198 | Oakland Athletics | Vermont (A-) | Assigned to Vermont (A-) |
| Ty Afenir | IF | 21.335 | New York Yankees | Charleston (sc) (A) | Assigned to Charleston (Sc) (A) |
| Sharif Othman | C | 24.125 | Miami Marlins | Greensboro (A) | Assigned to Greensboro (A) |
| Travious Relaford | SS | 21.074 | San Francisco Giants | Augusta (A) | Assigned to Augusta (A) |
| Nic Cuckovich | 3B | 21.292 | Kansas City Royals | Lexington (A) | Assigned to Lexington (A) |
| Danny Bethea | C | 23.176 | Boston Red Sox | Lowell (A-) | Assigned to Lowell (A-) |
| Nathan Minnich | 1B | 23.005 | Boston Red Sox | Lowell (A-) | Assigned to Lowell (A-) |
| Jose Fernandez | SS | 20.067 | Houston Astros | Gulf Coast Astros (Rk) | Assigned to Gulf Coast Astros (Rk) |
| Reynaldo Bruguera | | 21.264 | San Diego Padres | Arizona Padres (Rk) | Assigned to Arizona Padres (Rk) |
| Eric Arnett | P | 25.183 | Milwaukee Brewers | Arizona Brewers (Rk) | Assigned to Arizona Brewers (Rk) |
| Ryan Vogelsong | SP | 36.004 | San Francisco Giants | San Jose (A+) | Assigned to San Jose (A+) for rehab |
| Brent Leach | P | 30.250 | Milwaukee Brewers | Nashville (AAA) | Assigned to Nashville (AAA) |
| Sean Gallagher | P | 27.208 | Colorado Rockies | Colorado Springs (AAA) | Assigned to Colorado Springs (AAA) |
| Josh Tomlin | P | 28.280 | Cleveland Indians | Arizona Indians (Rk) | Assigned to Arizona Indians (Rk) for rehab |
| Ryan Verdugo | P | 26.107 | Kansas City Royals | Arizona Royals (Rk) | Assigned to Arizona Royals (Rk) |
| Sam Runion | P | 24.259 | Kansas City Royals | Northwest Arkansas (AA) | Assigned to Northwest Arkansas (AA) |
| Greg Peavey | P | 25.015 | New York Mets | Binghamton (AA) | Assigned to Binghamton (AA) |
| Jairo Heredia | P | 23.291 | New York Yankees | Tampa (A+) | Assigned to Tampa (A+) |
| Brett Anderson | SS | 22.326 | Texas Rangers | Spokane (A-) | Assigned to Spokane (A-) |
| Kirk Singer | 2B-SS | 23.237 | Pittsburgh Pirates | Gulf Coast Pirates (Rk) | Assigned to Gulf Coast Pirates (Rk) |
| Jorge De Leon | P | 25.346 | Houston Astros | Oklahoma City (AAA) | Assigned to Oklahoma City (AAA) |
| Luke Bard | P | 22.255 | Minnesota Twins | Gulf Coast Twins (Rk) | Assigned to Gulf Coast Twins (Rk) |
| Brady Rodgers | P | 22.312 | Houston Astros | Corpus Christi (AA) | Assigned to Corpus Christi (AA) |
| Ben Tomchick | P | 23.221 | Kansas City Royals | Lexington (A) | Assigned to Lexington (A) |
| Robert Rogers | P | 22.274 | Los Angeles Dodgers | Great Lakes (A) | Assigned to Great Lakes (A) |
| Armando Rodriguez | P | 25.180 | New York Mets | Binghamton (AA) | Assigned to Binghamton (AA) |
| Colby Holmes | P | 22.275 | Atlanta Braves | Gulf Coast Braves (Rk) | Assigned to Gulf Coast Braves (Rk) |
| Garrett Hughes | P-1B | 21.334 | San Francisco Giants | Arizona Giants (Rk) | |
| Christian Jones | P | 22.180 | San Francisco Giants | Salem-Keizer (A-) | Assigned to Salem-Keizer (A-) |
| Lex Rutledge | P | 22.028 | Baltimore Orioles | Frederick (A+) | Assigned to Frederick (A+) |
| Bladimir Franco | 3B-RF | 22.172 | Los Angeles Dodgers | Arizona Dodgers (Rk) | Assigned to Arizona Dodgers (Rk) |
| Michael Johnson | P | 22.204 | Los Angeles Dodgers | Ogden (Rk) | Assigned to Ogden (Rk) |
| Jerry Mulderig | OF | 21.039 | Pittsburgh Pirates | Gulf Coast Pirates (Rk) | |
| Trevor Clifton | P | 18.076 | Chicago Cubs | Arizona Cubs (Rk) | |
| Denton Keys | P | 18.299 | Philadelphia Phillies | Gulf Coast Phillies (Rk) | |
| Mike Adams | P | 22.295 | Boston Red Sox | Lowell (A-) | Signed out of draft |
| Clinton Hollon | P | 18.214 | Toronto Blue Jays | Gulf Coast Blue Jays (Rk) | |
| Oderman Rocha | | 20.261 | Pittsburgh Pirates | Gulf Coast Pirates (Rk) | Assigned to Gulf Coast Pirates (Rk) |
| Luis Guillen | P | 19.222 | Chicago Cubs | Arizona Cubs (Rk) | |
| Bruedlin Suero | P | 23.148 | Tampa Bay Rays | Charlotte (A+) | Assigned to Charlotte (A+) |
| Enmanuel de Jesus | P | 19.201 | | | Released by Giants |
| Josh Vitters | 3b | 23.333 | Chicago Cubs | Iowa (AAA) | DL-7 Injured |
| Corey Black | P | 21.357 | Chicago Cubs | Daytona (A+) | Traded from Yankees to Cubs for Alfonso Soriano |
