| Dana Eveland | RP | 28.259 | Baltimore Orioles | Baltimore Orioles (MLB) | Designated for Assignment |
| Ronny Paulino | c | 31.084 | Baltimore Orioles | Norfolk (AAA) | Outrighted to Norfolk (AAA) |
| Miguel Socolovich | P | 25.355 | Baltimore Orioles | Baltimore Orioles (MLB) | Contract purchased from Norfolk (AAA) |
| Taylor Teagarden | c | 28.206 | Baltimore Orioles | Baltimore Orioles (MLB) | Activated from DL |
| Mauro Gomez | 3b | 27.310 | Boston Red Sox | Pawtucket (AAA) | Optioned to Pawtucket (AAA) |
| Jerome Williams | RP-SP | 30.222 | Los Angeles Angels | Los Angeles Angels (MLB) | Activated from DL |
| Luis Marte | RP | 25.322 | Detroit Tigers | Detroit Tigers (MLB) | Recalled from Toledo (AAA) |
| Drew Smyly | SP | 23.031 | Detroit Tigers | Detroit Tigers (MLB) | DL-15 Right intercostal strain |
| Mitch Maier | LF-RF | 30.014 | Kansas City Royals | Omaha (AAA) | Outrighted to Omaha (AAA) |
| J.C. Boscan | C | 32.201 | Atlanta Braves | Gwinnett (AAA) | Optioned to Gwinnett (AAA) |
| Brian McCann | c | 28.145 | Atlanta Braves | Atlanta Braves (MLB) | Activated from Paternity List |
| Tyler Pastornicky | 2b | 22.213 | Atlanta Braves | Atlanta Braves (MLB) | Recalled from Gwinnett (AAA) |
| Javy Guerra | RP | 26.256 | Los Angeles Dodgers | Los Angeles Dodgers (MLB) | Placed on Bereavement list |
| Lance Berkman | 1b | 36.155 | St. Louis Cardinals | St. Louis Cardinals (MLB) | Activated from DL |
| Brian Fuentes | RP | 36.340 | St. Louis Cardinals | St. Louis Cardinals (MLB) | Signed to minor league contract |
| Patrick Corbin | RP | 22.360 | Arizona Diamondbacks | Reno (AAA) | Optioned to Reno (AAA) |
| Joe Saunders | SP | 31.028 | Arizona Diamondbacks | Arizona Diamondbacks (MLB) | Activated from DL |
| Shane Robinson | cf | 27.257 | St. Louis Cardinals | Memphis (AAA) | Optioned to Memphis (AAA) |
| Brad Mills | SP | 27.131 | Los Angeles Angels | Salt Lake (AAA) | Optioned to Salt Lake (AAA) |
| Andrelton Simmons | ss | 22.313 | Atlanta Braves | Atlanta Braves (MLB) | DL-15 Broken right pinkie finger |
| Darin Downs | RP | 27.200 | Detroit Tigers | Detroit Tigers (MLB) | Recalled from Toledo (AAA) |
| Rafael Perez | P | 30.060 | Cleveland Indians | Akron (AA) | Assigned to Akron (AA) for rehab |
| Luis Martinez | C | 27.102 | Texas Rangers | Texas Rangers (MLB) | Recalled from Round Rock (AAA) |
| Yoshinori Tateyama | RP | 36.201 | Texas Rangers | Round Rock (AAA) | Optioned to Round Rock (AAA) |
| Koji Uehara | P | 37.102 | Texas Rangers | Round Rock (AAA) | Assigned to Round Rock (AAA) for rehab |
| Todd Redmond | P | 27.058 | Cincinnati Reds | Louisville (AAA) | Traded from Braves to Reds for Paul Janish |
| Paul Janish | ss | 29.275 | Atlanta Braves | Atlanta Braves (MLB) | Traded from Reds to Braves for Todd Redmond |
| Jack Wilson | ss | 34.197 | Atlanta Braves | Atlanta Braves (MLB) | DL-15 Dislocated finger |
| Josh Wall | RP | 25.174 | Los Angeles Dodgers | Los Angeles Dodgers (MLB) | Recalled from Albuquerque (AAA) |
| Alex Presley | lf | 26.354 | Pittsburgh Pirates | Indianapolis (AAA) | Assigned to Indianapolis (AAA) for rehab |
| Humberto Quintero | C | 32.347 | Miami Marlins | New Orleans (AAA) | Signed to minor league contract |
| Neftali Feliz | P | 24.073 | Texas Rangers | Round Rock (AAA) | Assigned to Round Rock (AAA) for rehab |
| Lou Montanez | LF | 30.211 | St. Louis Cardinals | Memphis (AAA) | DL-7 Injured |
| Tommy Mendonca | 3B | 24.093 | Texas Rangers | Round Rock (AAA) | Activated from DL |
| Jason Bay | LF | 33.297 | New York Mets | Buffalo (AAA) | Assigned to Buffalo (AAA) for rehab |
| Chris Marrero | 1B | 24.012 | Washington Nationals | Syracuse (AAA) | DL-7 Injured |
| Zach Miner | P | 30.124 | Detroit Tigers | Toledo (AAA) | Activated from DL |
| Colin Curtis | OF | 27.163 | New York Yankees | Scranton/Wilkes-Barre (AAA) | DL-7 Injured |
| Kevin Russo | 2B | 28.006 | New York Yankees | Scranton/Wilkes-Barre (AAA) | Activated from DL |
| Lester Oliveros | P | 24.047 | Minnesota Twins | Rochester (AAA) | Activated from DL |
| Bill Hall | 2B | 32.199 | Baltimore Orioles | Norfolk (AAA) | DL-7 Left hamstring |
| Chris Robinson | C | 28.063 | Baltimore Orioles | Norfolk (AAA) | Activated from DL |
| Jeff Howell | C | 29.104 | Washington Nationals | Syracuse (AAA) | Activated from DL |
| Zechry Zinicola | P | 27.134 | Washington Nationals | Harrisburg (AA) | DL-7 Injured |
| Jeremie Tice | 1B | 25.292 | Cleveland Indians | Akron (AA) | DL-7 Injured |
| Scott Krieger | RF-LF | 25.165 | - | | Released by Brewers |
| J.T. Wise | C | 26.042 | Los Angeles Dodgers | Chattanooga (AA) | DL-7 Injured |
| Jordan Parraz | RF | 27.279 | Atlanta Braves | Gwinnett (AAA) | Assigned to Gwinnett (AAA) |
| Matt Rizzotti | 1B | 26.202 | Oakland Athletics | Midland (AA) | Signed as Free Agent. |
| Ryan Rohlinger | SS | 28.281 | Cleveland Indians | Akron (AA) | Assigned to Akron (AA) |
| Ryan Dent | SS | 23.121 | Boston Red Sox | Pawtucket (AAA) | Assigned to Pawtucket (AAA) |
| Evan Chambers | CF | 23.112 | Pittsburgh Pirates | Bradenton (A+) | Assigned to Bradenton (A+) |
| Kes Carter | CF | 22.133 | Tampa Bay Rays | Gulf Coast Rays (Rk) | |
| Kai Gronauer | C | 25.228 | New York Mets | St. Lucie (A+) | Assigned to St. Lucie (A+) |
| Danny Muno | SS | 23.155 | New York Mets | St. Lucie (A+) | |
| Kolbrin Vitek | 3B | 23.104 | Boston Red Sox | Gulf Coast Red Sox (Rk) | |
| Danny Stienstra | 2B-3B | 23.135 | St. Louis Cardinals | Gulf Coast Cardinals (Rk) | |
| Chris Peters | 2B-SS | 23.197 | Toronto Blue Jays | Lansing (A) | Assigned to Lansing (A) |
| Cade Kreuter | 3B | 21.078 | San Diego Padres | Arizona Padres (Rk) | |
| Jan Vazquez | C | 21.076 | Los Angeles Dodgers | Rancho Cucamonga (A+) | Assigned to Rancho Cucamonga (A+) |
| Jerome Pena | 2B | 23.250 | Baltimore Orioles | Delmarva (A) | Assigned to Delmarva (A) |
| Mike Zunino | C | 21.111 | Seattle Mariners | Everett (A-) | |
| Beau Taylor | C | 22.151 | Oakland Athletics | Midland (AA) | Assigned to Midland (AA) |
| Brian McConkey | 1B | 23.209 | Miami Marlins | Gulf Coast Marlins (Rk) | |
| Roberto De La Cruz | 3B | 21.246 | Colorado Rockies | Tri-City (A-) | Assigned to Tri-City (A-) |
| Roberto De La Cruz | 3B | 21.246 | St. Louis Cardinals | Quad Cities (A) | Assigned to Quad Cities (A) |
| Jared Reaves | IF | 21.359 | Detroit Tigers | Connecticut (A-) | Assigned to Connecticut (A-) |
| Rio Ruiz | 3B | 18.053 | Houston Astros | Gulf Coast Astros (Rk) | Assigned to Gulf Coast Astros (Rk) |
| Boof Bonser | P | 30.273 | San Francisco Giants | Fresno (AAA) | Assigned to Fresno (AAA) |
| Cory Riordan | P | 26.050 | Colorado Rockies | Colorado Springs (AAA) | Assigned to Colorado Springs (AAA) |
| David Phelps | RP-SP | 25.278 | New York Yankees | Scranton/Wilkes-Barre (AAA) | Assigned to Scranton/Wilkes-Barre (AAA) |
| Tommy Toledo | P | 23.213 | Milwaukee Brewers | Brevard County (A+) | Assigned to Brevard County (A+) |
| Chris Kissock | P | 27.073 | Philadelphia Phillies | Clearwater (A+) | Assigned to Clearwater (A+) |
| Justin Grimm | RP | 23.332 | Texas Rangers | Round Rock (AAA) | Assigned to Round Rock (AAA) |
| Stephen Pryor | P | 22.356 | Seattle Mariners | Tacoma (AAA) | Assigned to Tacoma (AAA) for rehab |
| Trey Haley | P | 22.023 | Cleveland Indians | Arizona Indians (Rk) | |
| Mike Montgomery | P | 23.013 | Kansas City Royals | Northwest Arkansas (AA) | Assigned to Northwest Arkansas (AA) |
| Tyler Chatwood | RP | 22.210 | Colorado Rockies | Tulsa (AA) | Assigned to Tulsa (AA) |
| Danny Jimenez | P | 22.294 | Cleveland Indians | Arizona Indians (Rk) | |
| Shawn Armstrong | P | 21.306 | Cleveland Indians | Akron (AA) | Assigned to Akron (AA) |
| Leondy Perez | P | 22.025 | Kansas City Royals | Arizona Royals (Rk) | |
| Chris Haney | P | 23.151 | San Diego Padres | Lake Elsinore (A+) | Assigned to Lake Elsinore (A+) |
| Brett Weibley | IF | 23.192 | Texas Rangers | Arizona Rangers (Rk) | |
| David Baker | P | 21.088 | Baltimore Orioles | Delmarva (A) | Assigned to Delmarva (A) |
| Chad Smith | P | 22.285 | Detroit Tigers | Connecticut (A-) | Assigned to Connecticut (A-) |
| Justin Amlung | P | 22.054 | Chicago Cubs | Arizona Cubs (Rk) | Assigned to Arizona Cubs (Rk) |
| Matt Flemer | P-1B | 21.234 | Colorado Rockies | Tri-City (A-) | |
| Louis Head | P | 22.082 | Cleveland Indians | Lake County (A) | Assigned to Lake County (A) |
| Robinson Yambati | P | 21.180 | Kansas City Royals | Wilmington (A+) | Assigned to Wilmington (A+) |
| Rafael Martin | P | 28.059 | Washington Nationals | Harrisburg (AA) | Assigned to Harrisburg (AA) |
| Jon Moscot | P | 20.334 | Cincinnati Reds | Billings (Rk) | Assigned to Billings (Rk) |
| Juri Perez | | 21.340 | Houston Astros | Lexington (A) | Assigned to Lexington (A) |
| Luis Meza | P | 22.001 | Los Angeles Dodgers | Arizona Dodgers (Rk) | |
| Lucas Sims | P | 18.065 | Atlanta Braves | Danville (Rk) | Assigned to Danville (Rk) |
| Kieran Lovegrove | P | 17.351 | Cleveland Indians | Arizona Indians (Rk) | |
| Paul Blackburn | P | 18.222 | Chicago Cubs | Arizona Cubs (Rk) | |
| Benny Suarez | P | 20.290 | Cleveland Indians | Arizona Indians (Rk) | Assigned to Arizona Indians (Rk) |
| Clay Buchholz | SP | 27.334 | Boston Red Sox | Boston Red Sox (MLB) | Activated from DL |
| Dioner Navarro | C | 28.156 | Cincinnati Reds | Louisville (AAA) | DL-7 Strained left hamstring |
