| Harry Agganis | 1B | 23.256 | Signed as undrafted amateur Free Agent by Red Sox. | |
| George Alusik | OF | 17.324 | Signed as undrafted amateur Free Agent by Tigers. | |
| Harry Anderson | OF-1B | 21.113 | Signed as undrafted amateur Free Agent by Phillies. | |
| Sparky Anderson | 2B | 18.313 | Signed as undrafted amateur Free Agent by Dodgers. | |
| Rudy Arias | P | 21.209 | Signed as undrafted amateur Free Agent by White Sox. | |
| Frank Barnes | P | 24.128 | Returned to Toronto (International) after expiration of minor league working agreement. | |
| Earl Battey | C | 17.361 | Signed as undrafted amateur Free Agent by White Sox. | |
| Ron Blackburn | P | 17.253 | Signed as undrafted amateur Free Agent by Pirates. | |
| Don Blasingame | 2B | 20.291 | Signed as undrafted amateur Free Agent by Cardinals. | |
| Bob Blaylock | P | 17.187 | Signed as undrafted amateur Free Agent by Cardinals. | |
| Don Bradey | P | 18.089 | Signed as undrafted amateur Free Agent by White Sox. | |
| Jackie Brandt | OF | 18.248 | Signed as undrafted amateur Free Agent by Cardinals. | |
| Fritz Brickell | SS | 17.288 | Signed as undrafted amateur Free Agent by Yankees. | |
| Marshall Bridges | P | 21.213 | Signed as undrafted amateur Free Agent by Giants. | |
| Dick Brown | C | 17.349 | Signed as undrafted amateur Free Agent by Indians. | |
| Bob Bruce | P | 19.228 | Signed as undrafted amateur Free Agent by Tigers. | |
| Tex Clevenger | P | 20.176 | Signed as undrafted amateur Free Agent by Red Sox. | |
| Gordy Coleman | 1B | 18.180 | Signed as undrafted amateur Free Agent by Indians. | |
| Bill Dailey | P | 17.233 | Signed as undrafted amateur Free Agent by Indians. | |
| Chuck Daniel | P | 19.106 | Signed as undrafted amateur Free Agent by Tigers. | |
| Bob Darnell | P | 22.056 | Signed as undrafted amateur Free Agent by Dodgers. | |
| Yo-Yo Davalillo | SS | 21.185 | Signed as undrafted amateur Free Agent by Senators. | |
| Don Demeter | OF | 17.190 | Signed as undrafted amateur Free Agent by Dodgers. | |
| Steve Demeter | 3B | 17.339 | Signed as undrafted amateur Free Agent by Tigers. | |
| Whammy Douglas | P | 17.318 | Signed as undrafted amateur Free Agent by Pirates. | |
| Joe Durham | OF | 21.154 | Signed as undrafted amateur Free Agent by Browns. | |
| Frank Ernaga | OF | 22.132 | Signed as undrafted amateur Free Agent by Cubs. | |
| Turk Farrell | P | 18.268 | Signed as undrafted amateur Free Agent by Phillies. | |
| John Fitzgerald | P | 19.108 | Signed as undrafted amateur Free Agent by Giants. | |
| Eddie Haas | OF | 17.220 | Signed as undrafted amateur Free Agent by Cubs. | |
| Earl Hersh | OF | 20.225 | Signed as undrafted amateur Free Agent by Braves. | |
| Joe Hicks | OF | 19.269 | Signed as undrafted amateur Free Agent by White Sox. | |
| Fred Hutchinson | P | 33.142 | Signed as Free Agent by Tigers. | |
| Johnny James | P | 19.162 | Signed as undrafted amateur Free Agent by Yankees. | |
| Lou Johnson | OF | 18.101 | Signed as undrafted amateur Free Agent by Yankees. | |
| Sherman Jones | P | 17.325 | Signed as undrafted amateur Free Agent by Giants. | |
| John Kennedy | 3B | 26.081 | Signed as undrafted Free Agent by Giants. | |
| Fred Kipp | P | 21.092 | Signed as undrafted amateur Free Agent by Dodgers. | |
| Marty Kutyna | P | 20.048 | Signed as undrafted amateur Free Agent by Cardinals. | |
| Bobby Locke | P | 18.304 | Signed as undrafted amateur Free Agent by Indians. | |
| Jim Mahoney | SS | 18.220 | Signed as undrafted amateur Free Agent by Phillies. | |
| Roger Maris | OF | 18.113 | Signed as undrafted amateur Free Agent by Indians. | |
| Ralph Mauriello | P | 18.129 | Signed as undrafted amateur Free Agent by Dodgers. | |
| Joe McClain | P | 19.241 | Signed as undrafted amateur Free Agent by Cardinals. | |
| Roman Mejias | OF | 22.145 | Signed as undrafted amateur Free Agent by Pirates. | |
| Russ Nixon | C | 17.316 | Signed as undrafted amateur Free Agent by Indians. | |
| Bobo Osborne | 1B-3B | 17.081 | Signed as undrafted amateur Free Agent by Tigers. | |
| Tom Patton | C | 17.118 | Signed as undrafted amateur Free Agent by Cardinals. | |
| Albie Pearson | OF | 18.111 | Signed as undrafted amateur Free Agent by Red Sox. | |
| Bob Perry | OF | 18.109 | Signed as undrafted amateur Free Agent by Giants. | |
| Pedro Ramos | P | 17.248 | Signed as undrafted amateur Free Agent by Senators. | |
| Curt Raydon | P | 19.044 | Signed as undrafted amateur Free Agent by Braves. | |
| Jack Reed | OF | 19.333 | Signed as undrafted amateur Free Agent by Yankees. | |
| Rudy Regalado | 3B | 22.225 | Signed as undrafted amateur Free Agent by Indians. | |
| Bobby Richardson | 2B | 17.135 | Signed as undrafted amateur Free Agent by Yankees. | |
| Frank Robinson | OF | 17.123 | Signed as undrafted amateur Free Agent by Reds. | |
| Ken Rowe | P | 19.001 | Signed as undrafted amateur Free Agent by Tigers. | |
| Bob Shaw | P | 19.186 | Signed as undrafted amateur Free Agent by Tigers. | |
| Larry Sherry | P | 17.160 | Signed as undrafted amateur Free Agent by Dodgers. | |
| Dave Sisler | P | 21.077 | Signed as undrafted amateur Free Agent by Red Sox. | |
| Bill Smith | P | 18.207 | Signed as undrafted amateur Free Agent by Cardinals. | |
| Russ Snyder | OF | 18.193 | Signed as undrafted amateur Free Agent by Yankees. | |
| Walt Streuli | C | 17.097 | Signed as undrafted amateur Free Agent by Tigers. | |
| Bill Taylor | OF | 23.002 | Signed as undrafted Free Agent by Giants. | |
| Bob Thorpe | P | 17.354 | Signed as undrafted amateur Free Agent by Cubs. | |
| Dick Tracewski | SS-2B | 17.332 | Signed as undrafted amateur Free Agent by Dodgers. | |
| Ozzie Virgil | 3B | 19.229 | Signed as undrafted amateur Free Agent by Giants. | |
| Bill White | 1B | 18.338 | Signed as undrafted amateur Free Agent by Giants. | |
| Don Williams | P | 21.109 | Signed as undrafted amateur Free Agent by Pirates. | |
| Casey Wise | 2B-SS | 20.115 | Signed as undrafted amateur Free Agent by Cubs. | |
| Roy Wright | P | 19.097 | Signed as undrafted amateur Free Agent by Cardinals. | |
