| 2005-04-04 | Box | at SEA | 1 | L 1-5 | 0-1 | 46,249 | 2:22 | Jamie Moyer | Brad Radke | none | | 2005-04-05 | Box | at SEA | 2 | W 8-4 | 1-1 | 28,373 | 3:01 | Johan Santana | Matt Thornton | none | | 2005-04-06 | Box | at SEA | 3 | W 4-1 | 2-1 | 25,580 | 2:24 | Carlos Silva | Bobby Madritsch | Joe Nathan | | 2005-04-08 | Box | vs CHA | 4 | L 1-5 | 2-2 | 48,764 | 2:46 | Orlando Hernandez | Kyle Lohse | none | | 2005-04-09 | Box | vs CHA | 5 | L 5-8 | 2-3 | 41,533 | 2:37 | Jon Garland | Brad Radke | Shingo Takatsu | | 2005-04-10 | Box | vs CHA | 6 | W 5-2 | 3-3 | 28,089 | 2:29 | Johan Santana | Mark Buehrle | Joe Nathan | | 2005-04-12 | Box | vs DET | 7 | W 5-4 | 4-3 | 15,071 | 2:52 | Juan Rincon | Troy Percival | none | | 2005-04-13 | Box | vs DET | 8 | W 8-4 | 5-3 | 16,067 | 2:39 | Kyle Lohse | Jason Johnson | none | | 2005-04-14 | Box | vs DET | 9 | W 10-4 | 6-3 | 14,344 | 2:47 | Brad Radke | Nate Robertson | none | | 2005-04-15 | Box | at CLE | 10 | W 3-2 | 7-3 | 15,360 | 2:47 | Johan Santana | Jake Westbrook | Joe Nathan | | 2005-04-16 | Box | at CLE | 11 | W 6-4 | 8-3 | 18,699 | 2:35 | Dave Gassner | Kevin Millwood | Joe Nathan | | 2005-04-17 | Box | at CLE | 12 | L 1-2 | 8-4 | 19,021 | 2:12 | Bob Howry | J.C. Romero | Bob Wickman | | 2005-04-18 | Box | at CHA | 13 | L 4-5 | 8-5 | 27,018 | 2:47 | Luis Vizcaino | Kyle Lohse | Shingo Takatsu | | 2005-04-19 | Box | at CHA | 14 | L 1-3 | 8-6 | 18,310 | 2:40 | Orlando Hernandez | Brad Radke | Damaso Marte | | 2005-04-20 | Box | vs KCA | 15 | W 5-4 | 9-6 | 24,153 | 2:37 | Juan Rincon | Jaime Cerda | Joe Nathan | | 2005-04-21 | Box | vs KCA | 16 | W 10-9 | 10-6 | 15,914 | 3:32 | Joe Nathan | Shawn Camp | none | | 2005-04-22 | Box | at DET | 17 | L 4-5 | 10-7 | 18,873 | 0:00 | Troy Percival | Terry Mulholland | none | | 2005-04-25 | Box | at DET | 18 | L 4-6 | 10-8 | 14,976 | 3:03 | Kyle Farnsworth | Juan Rincon | Troy Percival | | 2005-04-26 | Box | at KCA | 19 | W 2-1 | 11-8 | 10,133 | 2:40 | Johan Santana | Ambiorix Burgos | Joe Nathan | | 2005-04-27 | Box | at KCA | 20 | W 9-4 | 12-8 | 10,393 | 2:37 | Joe Mays | Brian Anderson | none | | 2005-04-28 | Box | at KCA | 21 | W 6-5 | 13-8 | 10,852 | 3:37 | Jesse Crain | Mike Wood | none | | 2005-04-29 | Box | vs ANA | 22 | W 7-4 | 14-8 | 29,866 | 2:31 | Carlos Silva | Paul Byrd | Joe Nathan | | 2005-04-30 | Box | vs ANA | 23 | W 4-2 | 15-8 | 31,576 | 2:26 | Brad Radke | Kelvim Escobar | Joe Nathan | | 2005-05-01 | Box | vs ANA | 24 | L 1-2 | 15-9 | 30,837 | 2:24 | Bartolo Colon | Johan Santana | Francisco Rodriguez | | 2005-05-03 | Box | vs CLE | 25 | L 2-4 | 15-10 | 16,919 | 3:09 | Jake Westbrook | Joe Mays | Bob Wickman | | 2005-05-04 | Box | vs CLE | 26 | L 4-5 | 15-11 | 19,856 | 2:39 | Bob Howry | J.C. Romero | Bob Wickman | | 2005-05-05 | Box | vs CLE | 27 | W 9-0 | 16-11 | 18,265 | 2:26 | Brad Radke | C.C. Sabathia | none | | 2005-05-06 | Box | at TBA | 28 | W 7-1 | 17-11 | 8,884 | 2:22 | Johan Santana | Dewon Brazelton | none | | 2005-05-07 | Box | at TBA | 29 | W 8-1 | 18-11 | 12,675 | 2:43 | Kyle Lohse | Scott Kazmir | none | | 2005-05-08 | Box | at TBA | 30 | W 9-6 | 19-11 | 9,519 | 2:50 | Joe Mays | Doug Waechter | Joe Nathan | | 2005-05-09 | Box | at BAL | 31 | L 0-3 | 19-12 | 17,310 | 2:23 | Daniel Cabrera | Carlos Silva | B.J. Ryan | | 2005-05-10 | Box | at BAL | 32 | W 6-4 | 20-12 | 22,410 | 3:18 | Jesse Crain | Steve Kline | Joe Nathan | | 2005-05-11 | Box | at BAL | 33 | L 4-7 | 20-13 | 28,575 | 2:53 | Sidney Ponson | Matt Guerrier | B.J. Ryan | | 2005-05-13 | Box | vs TEX | 34 | L 6-9 | 20-14 | 24,524 | 3:27 | Doug Brocail | Joe Nathan | Francisco Cordero | | 2005-05-14 | Box | vs TEX | 35 | L 0-5 | 20-15 | 28,624 | 2:07 | Kenny Rogers | Carlos Silva | none | | 2005-05-15 | Box | vs TEX | 36 | W 5-2 | 21-15 | 27,891 | 2:35 | Brad Radke | Ron Mahay | Joe Nathan | | 2005-05-17 | Box | vs TOR | 37 | L 3-10 | 21-16 | 18,717 | 2:49 | Josh Towers | Johan Santana | none | | 2005-05-18 | Box | vs TOR | 38 | W 3-2 | 22-16 | 23,929 | 2:16 | Kyle Lohse | David Bush | Joe Nathan | | 2005-05-19 | Box | vs TOR | 39 | W 4-0 | 23-16 | 22,680 | 2:20 | Joe Mays | Gustavo Chacin | none | | 2005-05-20 | Box | vs MIL | 40 | W 7-1 | 24-16 | 30,073 | 2:27 | Carlos Silva | Gary Glover | none | | 2005-05-21 | Box | vs MIL | 41 | L 0-6 | 24-17 | 32,106 | 2:34 | Doug Davis | Brad Radke | none | | 2005-05-22 | Box | vs MIL | 42 | W 6-5 | 25-17 | 28,466 | 3:45 | Jesse Crain | Matt Wise | none | | 2005-05-23 | Box | at CLE | 43 | L 1-2 | 25-18 | 13,257 | 2:38 | Arthur Rhodes | Kyle Lohse | Bob Wickman | | 2005-05-24 | Box | at CLE | 44 | W 6-3 | 26-18 | 15,884 | 3:30 | Jesse Crain | David Riske | Joe Nathan | | 2005-05-25 | Box | at CLE | 45 | L 2-3 | 26-19 | 15,794 | 3:00 | Bob Howry | Juan Rincon | none | | 2005-05-26 | Box | at CLE | 46 | W 5-4 | 27-19 | 19,161 | 3:23 | Jesse Crain | David Riske | Joe Nathan | | 2005-05-27 | Box | at TOR | 47 | W 7-2 | 28-19 | 18,702 | 2:28 | Johan Santana | Josh Towers | none | | 2005-05-28 | Box | at TOR | 48 | W 4-3 | 29-19 | 29,263 | 2:16 | Kyle Lohse | David Bush | Joe Nathan | | 2005-05-29 | Box | at TOR | 49 | L 0-4 | 29-20 | 24,287 | 2:08 | Roy Halladay | Joe Mays | none | | | 2005-05-31 | Box | vs CLE | 50 | L 3-4 | 29-21 | 15,494 | 2:28 | C.C. Sabathia | Carlos Silva | Bob Wickman | | 2005-06-01 | Box | vs CLE | 51 | W 6-2 | 30-21 | 20,739 | 2:36 | Brad Radke | Cliff Lee | none | | 2005-06-02 | Box | vs CLE | 52 | W 4-3 | 31-21 | 17,351 | 3:32 | J.C. Romero | Rafael Betancourt | none | | 2005-06-03 | Box | vs NYA | 53 | W 6-3 | 32-21 | 41,588 | 2:28 | Kyle Lohse | Mike Mussina | Joe Nathan | | 2005-06-04 | Box | vs NYA | 54 | L 3-4 | 32-22 | 45,553 | 2:59 | Tom Gordon | Joe Nathan | Mariano Rivera | | 2005-06-05 | Box | vs NYA | 55 | W 9-3 | 33-22 | 37,349 | 3:00 | Carlos Silva | Kevin Brown | none | | 2005-06-07 | Box | at ARI | 56 | W 9-8 | 34-22 | 27,901 | 2:53 | Juan Rincon | Jose Valverde | Joe Nathan | | 2005-06-08 | Box | at ARI | 57 | W 10-0 | 35-22 | 23,404 | 2:31 | Johan Santana | Claudio Vargas | none | | 2005-06-09 | Box | at ARI | 58 | L 3-4 | 35-23 | 22,139 | 2:36 | Javier Vazquez | Kyle Lohse | Brian Bruney | | 2005-06-10 | Box | at LAN | 59 | L 5-6 | 35-24 | 46,713 | 2:48 | Eric Gagne | Terry Mulholland | none | | 2005-06-11 | Box | at LAN | 60 | W 5-3 | 36-24 | 53,354 | 2:23 | Carlos Silva | Derek Lowe | Joe Nathan | | 2005-06-12 | Box | at LAN | 61 | L 3-4 | 36-25 | 54,368 | 2:36 | D.J. Houlton | Brad Radke | Eric Gagne | | 2005-06-14 | Box | vs SFN | 62 | W 4-3 | 37-25 | 23,145 | 3:07 | Jesse Crain | Jeff Fassero | none | | 2005-06-15 | Box | vs SFN | 63 | L 4-8 | 37-26 | 25,613 | 2:33 | Noah Lowry | Kyle Lohse | none | | 2005-06-16 | Box | vs SFN | 64 | L 7-14 | 37-27 | 18,815 | 3:24 | Jason Christiansen | Joe Nathan | none | | 2005-06-17 | Box | vs SDN | 65 | W 5-4 | 38-27 | 21,014 | 3:20 | Juan Rincon | Dennys Reyes | none | | 2005-06-18 | Box | vs SDN | 66 | L 2-7 | 38-28 | 26,235 | 2:46 | Brian Lawrence | Brad Radke | none | | 2005-06-19 | Box | vs SDN | 67 | L 1-5 | 38-29 | 31,371 | 2:24 | Darrell May | Johan Santana | none | | 2005-06-21 | Box | vs DET | 68 | L 2-7 | 38-30 | 20,839 | 2:38 | Jeremy Bonderman | Kyle Lohse | none | | 2005-06-22 | Box | vs DET | 69 | L 1-8 | 38-31 | 24,114 | 2:33 | Nate Robertson | Joe Mays | none | | 2005-06-23 | Box | vs DET | 70 | W 6-2 | 39-31 | 20,517 | 2:07 | Carlos Silva | Jason Johnson | none | | 2005-06-24 | Box | at MIL | 71 | L 1-3 | 39-32 | 36,023 | 3:03 | Chris Capuano | Brad Radke | Derrick Turnbow | | 2005-06-25 | Box | at MIL | 72 | L 6-7 | 39-33 | 44,685 | 2:50 | Matt Wise | Johan Santana | Derrick Turnbow | | 2005-06-26 | Box | at MIL | 73 | W 5-2 | 40-33 | 34,324 | 2:54 | Kyle Lohse | Victor Santos | none | | 2005-06-27 | Box | vs KCA | 74 | W 3-1 | 41-33 | 16,530 | 2:11 | Joe Mays | Zack Greinke | Joe Nathan | | 2005-06-28 | Box | vs KCA | 75 | W 11-8 | 42-33 | 19,422 | 2:53 | Jesse Crain | Andrew Sisco | Joe Nathan | | 2005-06-29 | Box | vs KCA | 76 | L 1-3 | 42-34 | 24,546 | 2:46 | D.J. Carrasco | Brad Radke | Mike MacDougal | | 2005-07-01 | Box | vs TBA | 77 | W 7-4 | 43-34 | 23,428 | 2:32 | Jesse Crain | Dewon Brazelton | Joe Nathan | | 2005-07-02 | Box | vs TBA | 78 | W 4-1 | 44-34 | 26,393 | 2:05 | Kyle Lohse | Seth McClung | Joe Nathan | | 2005-07-03 | Box | vs TBA | 79 | W 3-2 | 45-34 | 28,757 | 2:16 | Joe Mays | Scott Kazmir | Joe Nathan | | 2005-07-04 | Box | at ANA | 80 | W 7-5 | 46-34 | 44,008 | 2:52 | Carlos Silva | John Lackey | Joe Nathan | | 2005-07-05 | Box | at ANA | 81 | L 1-2 | 46-35 | 2,335 | 2:49 | Ervin Santana | Scott Baker | Francisco Rodriguez | | 2005-07-06 | Box | at ANA | 82 | L 6-7 | 46-36 | 41,534 | 2:43 | Joel Peralta | Johan Santana | Francisco Rodriguez | | 2005-07-07 | Box | at KCA | 83 | L 5-8 | 46-37 | 12,662 | 2:54 | Jose Lima | Kyle Lohse | none | | 2005-07-08 | Box | at KCA | 84 | W 5-4 | 47-37 | 20,554 | 2:38 | Brad Radke | Zack Greinke | Joe Nathan | | 2005-07-09 | Box | at KCA | 85 | L 8-12 | 47-38 | 26,023 | 3:32 | Leo Nunez | Jesse Crain | none | | 2005-07-10 | Box | at KCA | 86 | W 3-2 | 48-38 | 17,094 | 2:59 | J.C. Romero | Mike Wood | Jesse Crain | | 2005-07-14 | Box | vs ANA | 87 | L 2-3 | 48-39 | 21,979 | 2:53 | Jarrod Washburn | Kyle Lohse | Francisco Rodriguez | | 2005-07-15 | Box | vs ANA | 88 | L 2-3 | 48-40 | 25,920 | 2:24 | Paul Byrd | Brad Radke | Francisco Rodriguez | | 2005-07-16 | Box | vs ANA | 89 | W 5-4 | 49-40 | 34,009 | 2:59 | Johan Santana | Bartolo Colon | Joe Nathan | | 2005-07-17 | Box | vs ANA | 90 | L 1-2 | 49-41 | 30,367 | 2:20 | John Lackey | Joe Mays | Francisco Rodriguez | | 2005-07-18 | Box | vs BAL | 91 | L 2-3 | 49-42 | 20,308 | 2:58 | Jorge Julio | Juan Rincon | none | | 2005-07-19 | Box | vs BAL | 92 | W 4-3 | 50-42 | 26,183 | 3:18 | Jesse Crain | B.J. Ryan | none | | 2005-07-20 | Box | vs BAL | 93 | W 3-2 | 51-42 | 30,091 | 2:31 | Joe Nathan | Jason Grimsley | none | | 2005-07-21 | Box | at DET | 94 | W 10-5 | 52-42 | 23,769 | 3:08 | Johan Santana | Jason Johnson | none | | 2005-07-22 | Box | at DET | 95 | L 6-12 | 52-43 | 34,526 | 2:47 | Mike Maroth | Joe Mays | none | | 2005-07-23 (1) | Box | at DET | 96 | L 1-2 | 52-44 | 20,206 | 2:23 | Sean Douglass | Carlos Silva | Kyle Farnsworth | | 2005-07-23 (2) | Box | at DET | 97 | W 5-2 | 53-44 | 34,388 | 2:12 | Scott Baker | Justin Verlander | Joe Nathan | | 2005-07-24 | Box | at DET | 98 | L 2-5 | 53-45 | 27,966 | 2:22 | Jeremy Bonderman | Kyle Lohse | Kyle Farnsworth | | 2005-07-26 | Box | at NYA | 99 | L 0-4 | 53-46 | 53,855 | 2:30 | Randy Johnson | Brad Radke | none | | 2005-07-27 | Box | at NYA | 100 | W 7-3 | 54-46 | 50,334 | 3:42 | Johan Santana | Al Leiter | Joe Nathan | | 2005-07-28 | Box | at NYA | 101 | L 3-6 | 54-47 | 53,524 | 2:24 | Aaron Small | Joe Mays | Mariano Rivera | | 2005-07-29 | Box | at BOS | 102 | L 5-8 | 54-48 | 35,211 | 2:30 | Bronson Arroyo | Carlos Silva | Curt Schilling | | 2005-07-30 | Box | at BOS | 103 | L 2-6 | 54-49 | 35,167 | 2:58 | David Wells | Kyle Lohse | none | | 2005-07-31 | Box | at BOS | 104 | L 3-4 | 54-50 | 34,929 | 3:03 | Mike Timlin | Juan Rincon | Curt Schilling | | 2005-08-01 | Box | vs OAK | 105 | L 1-2 | 54-51 | 21,176 | 2:20 | Joe Blanton | Johan Santana | Huston Street | | 2005-08-02 | Box | vs OAK | 106 | L 2-5 | 54-52 | 22,101 | 2:35 | Dan Haren | J.C. Romero | Huston Street | | 2005-08-03 | Box | vs OAK | 107 | W 4-3 | 55-52 | 30,581 | 2:13 | Joe Nathan | Justin Duchscherer | none | | 2005-08-04 | Box | vs OAK | 108 | L 2-5 | 55-53 | 25,154 | 2:33 | Barry Zito | Jesse Crain | Huston Street | | 2005-08-05 | Box | vs BOS | 109 | W 12-0 | 56-53 | 38,161 | 2:57 | Brad Radke | Bronson Arroyo | none | | 2005-08-06 | Box | vs BOS | 110 | W 4-3 | 57-53 | 40,626 | 2:49 | Joe Nathan | Mike Timlin | none | | 2005-08-07 | Box | vs BOS | 111 | L 7-11 | 57-54 | 40,982 | 2:54 | Tim Wakefield | Joe Mays | Curt Schilling | | 2005-08-08 | Box | at SEA | 112 | L 4-5 | 57-55 | 35,401 | 2:29 | George Sherrill | Carlos Silva | Eddie Guardado | | 2005-08-09 | Box | at SEA | 113 | L 0-1 | 57-56 | 34,213 | 2:01 | Felix Hernandez | Kyle Lohse | Eddie Guardado | | 2005-08-10 | Box | at SEA | 114 | W 7-3 | 58-56 | 35,801 | 4:27 | Joe Nathan | Jeff Nelson | none | | 2005-08-12 | Box | at OAK | 115 | W 1-0 | 59-56 | 46,812 | 2:00 | Johan Santana | Dan Haren | none | | 2005-08-13 | Box | at OAK | 116 | L 2-5 | 59-57 | 47,385 | 2:38 | Kirk Saarloos | Joe Mays | Huston Street | | 2005-08-14 | Box | at OAK | 117 | W 2-1 | 60-57 | 29,067 | 2:04 | Juan Rincon | Justin Duchscherer | Joe Nathan | | 2005-08-15 | Box | at CHA | 118 | W 4-2 | 61-57 | 39,160 | 2:51 | Kyle Lohse | Jose Contreras | Joe Nathan | | 2005-08-16 | Box | at CHA | 119 | W 9-4 | 62-57 | 34,533 | 5:09 | J.C. Romero | Jon Adkins | none | | 2005-08-17 | Box | at CHA | 120 | W 5-1 | 63-57 | 33,158 | 2:34 | Johan Santana | Mark Buehrle | none | | 2005-08-18 | Box | vs SEA | 121 | W 7-3 | 64-57 | 22,230 | 2:48 | Joe Mays | Ryan Franklin | none | | 2005-08-19 | Box | vs SEA | 122 | W 7-4 | 65-57 | 24,795 | 2:40 | Carlos Silva | George Sherrill | Joe Nathan | | 2005-08-20 | Box | vs SEA | 123 | L 3-8 | 65-58 | 33,334 | 2:42 | George Sherrill | Matt Guerrier | none | | 2005-08-21 | Box | vs SEA | 124 | W 8-3 | 66-58 | 33,405 | 2:34 | Brad Radke | Joel Pineiro | none | | 2005-08-23 | Box | vs CHA | 125 | W 1-0 | 67-58 | 33,572 | 2:08 | Johan Santana | Freddy Garcia | Joe Nathan | | 2005-08-24 | Box | vs CHA | 126 | L 4-6 | 67-59 | 32,687 | 2:33 | Mark Buehrle | Joe Mays | Dustin Hermanson | | 2005-08-25 | Box | vs CHA | 127 | L 1-2 | 67-60 | 26,895 | 2:45 | Dustin Hermanson | Jesse Crain | Bobby Jenks | | 2005-08-26 | Box | at TEX | 128 | L 0-6 | 67-61 | 28,877 | 2:17 | Kameron Loe | Kyle Lohse | C.J. Wilson | | 2005-08-27 | Box | at TEX | 129 | W 7-2 | 68-61 | 25,351 | 3:30 | Joe Nathan | Brian Shouse | none | | 2005-08-28 | Box | at TEX | 130 | L 1-2 | 68-62 | 20,882 | 2:32 | Doug Brocail | Jesse Crain | none | | 2005-08-29 | Box | at KCA | 131 | W 3-1 | 69-62 | 13,555 | 2:51 | Juan Rincon | Shawn Camp | Joe Nathan | | 2005-08-30 | Box | at KCA | 132 | W 7-4 | 70-62 | 13,819 | 2:45 | Carlos Silva | Jose Lima | Joe Nathan | | 2005-08-31 | Box | at KCA | 133 | L 0-1 | 70-63 | 12,963 | 2:32 | Mike MacDougal | Matt Guerrier | none | | 2005-09-02 | Box | vs CLE | 134 | L 1-6 | 70-64 | 16,119 | 2:36 | C.C. Sabathia | Brad Radke | none | | 2005-09-03 | Box | vs CLE | 135 | W 3-2 | 71-64 | 21,757 | 2:29 | Joe Nathan | Bob Howry | none | | 2005-09-04 | Box | vs CLE | 136 | W 7-5 | 72-64 | 21,717 | 2:40 | Jesse Crain | Jake Westbrook | Joe Nathan | | 2005-09-05 | Box | vs TEX | 137 | L 0-7 | 72-65 | 15,627 | 2:12 | Kameron Loe | Carlos Silva | none | | 2005-09-06 | Box | vs TEX | 138 | L 7-10 | 72-66 | 12,564 | 2:51 | John Wasdin | Joe Nathan | Francisco Cordero | | 2005-09-07 | Box | vs TEX | 139 | W 8-6 | 73-66 | 13,034 | 2:59 | J.C. Romero | Doug Brocail | Joe Nathan | | 2005-09-09 | Box | at CLE | 140 | L 2-4 | 73-67 | 26,078 | 2:45 | Jake Westbrook | Johan Santana | Bob Wickman | | 2005-09-10 | Box | at CLE | 141 | L 5-7 | 73-68 | 32,123 | 2:42 | Scott Elarton | Scott Baker | Bob Wickman | | 2005-09-11 | Box | at CLE | 142 | L 4-12 | 73-69 | 38,564 | 2:59 | Cliff Lee | Carlos Silva | none | | 2005-09-12 | Box | at DET | 143 | W 2-1 | 74-69 | 12,748 | 2:43 | Kyle Lohse | Chris Spurling | Joe Nathan | | 2005-09-13 | Box | at DET | 144 | W 9-3 | 75-69 | 16,986 | 2:25 | Brad Radke | Nate Robertson | none | | 2005-09-14 | Box | at DET | 145 | L 2-4 | 75-70 | 19,438 | 2:26 | Craig Dingman | Juan Rincon | none | | 2005-09-16 | Box | vs CHA | 146 | L 1-2 | 75-71 | 26,951 | 2:49 | Bobby Jenks | Jesse Crain | none | | 2005-09-17 | Box | vs CHA | 147 | W 5-0 | 76-71 | 24,866 | 2:50 | Johan Santana | Orlando Hernandez | Joe Nathan | | 2005-09-18 | Box | vs CHA | 148 | L 1-2 | 76-72 | 23,559 | 2:17 | Jose Contreras | Juan Rincon | Bobby Jenks | | 2005-09-19 | Box | at OAK | 149 | L 6-7 | 76-73 | 15,262 | 3:05 | Barry Zito | Brad Radke | none | | 2005-09-20 | Box | at OAK | 150 | L 3-8 | 76-74 | 18,014 | 2:37 | Joe Blanton | Francisco Liriano | none | | 2005-09-21 | Box | at OAK | 151 | W 10-4 | 77-74 | 14,927 | 3:02 | Scott Baker | Joe Kennedy | none | | 2005-09-22 | Box | at CHA | 152 | W 4-1 | 78-74 | 25,112 | 3:12 | Jesse Crain | Bobby Jenks | Joe Nathan | | 2005-09-23 | Box | at CHA | 153 | L 1-3 | 78-75 | 28,003 | 2:19 | Jose Contreras | Kyle Lohse | none | | 2005-09-24 | Box | at CHA | 154 | L 1-8 | 78-76 | 37,699 | 2:27 | Freddy Garcia | Joe Mays | none | | 2005-09-25 | Box | at CHA | 155 | L 1-4 | 78-77 | 30,402 | 1:53 | Mark Buehrle | Francisco Liriano | none | | 2005-09-26 | Box | vs KCA | 156 | L 0-5 | 78-78 | 13,472 | 2:19 | J.P. Howell | Scott Baker | none | | 2005-09-27 | Box | vs KCA | 157 | W 3-1 | 79-78 | 16,147 | 2:30 | Johan Santana | Runelvys Hernandez | Joe Nathan | | 2005-09-28 | Box | vs KCA | 158 | W 6-3 | 80-78 | 14,982 | 2:46 | Jesse Crain | Andrew Sisco | Joe Nathan | | 2005-09-29 | Box | vs KCA | 159 | L 6-10 | 80-79 | 14,638 | 2:59 | D.J. Carrasco | Travis Bowyer | none | | 2005-09-30 | Box | vs DET | 160 | W 7-3 | 81-79 | 18,725 | 2:12 | Francisco Liriano | Mike Maroth | none | | 2005-10-01 | Box | vs DET | 161 | W 3-0 | 82-79 | 28,292 | 2:17 | Scott Baker | Jason Johnson | Joe Nathan | | 2005-10-02 | Box | vs DET | 162 | W 6-4 | 83-79 | 20,160 | 2:27 | Johan Santana | Nate Robertson | Joe Nathan | |
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